Development Level

Tclin 5 | 613
Tbio 4 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 2 | 298
decreased erythrocyte cell num... 2 | 62
decreased hemoglobin content 2 | 68
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased pulmonary respirator... 1 | 5
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123

Disease

Alcohol dependence 7 | 107
Alcoholic Intoxication, Chronic 7 | 289
Carcinoma 7 | 11,493
psoriasis 7 | 6,694
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
colon cancer 5 | 1,478
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alcohol abuse 4 | 50
Attention deficit hyperactivity disorder 4 | 278
Bipolar Disorder 4 | 666
Substance abuse 4 | 59
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
pituitary cancer 4 | 1,972
Alcoholism 3 | 45
Autistic Disorder 3 | 364
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Dementia 3 | 175
Depressive disorder 3 | 409
Heroin dependence 3 | 30
Liver disease 3 | 237
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Mood Disorders 3 | 184
Parkinson's disease 3 | 392
Pheochromocytoma 3 | 24
Schizophrenia 3 | 1,160
Succinic semialdehyde dehydrogenase deficiency 3 | 16
Unipolar Depression 3 | 250
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
esophageal cancer 3 | 22
medulloblastoma, large-cell 3 | 6,241
substance-related disorder 3 | 162
Alcoholic Intoxication 2 | 34
Alcoholic neuropathy 2 | 3
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Cocaine Dependence 2 | 51
Cognition Disorders 2 | 32
Colorectal Neoplasms 2 | 243
Conduct disorder 2 | 33
Depression, Bipolar 2 | 12
Endometriosis 2 | 540
Esophageal Neoplasms 2 | 69
Esophageal Squamous Cell Carcinoma 2 | 77
Flushing 2 | 60
Genetic Predisposition to Disease 2 | 27
Hangover from alcohol 2 | 2
Hepatic encephalopathy 2 | 27
Huntington Disease 2 | 13
Hypertension 2 | 396
Hypertensive disorder 2 | 56
Hypotension 2 | 82
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Mental disorders 2 | 12
Norrie disease 2 | 14
Pancreatitis 2 | 123
Parkinson Disease 2 | 64
Personality disorder 2 | 25
Psychotic Disorders 2 | 151
Short stature 2 | 531
Squamous cell carcinoma of esophagus 2 | 77
Toxic encephalopathy 2 | 141
Wernicke-Korsakoff syndrome 2 | 10
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
chronic rhinosinusitis 2 | 512
cystic fibrosis and chronic rhinosinusitis 2 | 214
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pancreatic cancer 2 | 2,398
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Acne 1 | 52
Eating disorder 1 | 26
Hyperkyphosis 1 | 111
Hypocalcemia 1 | 32
Hypoparathyroidism 1 | 41
Kyphosis deformity of spine 1 | 114
Marijuana Abuse 1 | 31
Musculoskeletal Pain 1 | 3
Pain 1 | 103
Plaque, Amyloid 1 | 2

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Enzyme 10 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
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http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme -0.92913 14.1 37
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
Phenylethanolamine N-methyltransferase PNMT Tchem Enzyme -2.90323 857.6 277
Alcohol dehydrogenase 4 ADH4 Tbio Enzyme -2.30746 247.9 210
Catechol O-methyltransferase COMT Tclin Enzyme -3.46304 2976.1 433
Alcohol dehydrogenase 1B ADH1B Tclin Enzyme -2.42307 381.5 160
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Amine oxidase [flavin-containing] A MAOA Tclin Enzyme -3.39309 2492.1 292
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470