Development Level

Tbio 6 | 11,445

IMPC Phenotype

decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased neutrophil cell numb... 1 | 42
hypoactivity 1 | 132
increased lymphocyte cell numb... 1 | 32
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 6 | 8,520
Carcinoma 4 | 11,493
ependymoma 4 | 4,679
oligodendroglioma 4 | 2,850
Brachydactyly 3 | 156
Cancer 3 | 2,499
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Hypoplasia of the maxilla 3 | 66
Hypotrophic maxilla 3 | 66
Maxillary retrognathia 3 | 66
Microstomia 3 | 78
Orbital separation excessive 3 | 244
Pick disease 3 | 1,894
Retrusion of upper jaw bones 3 | 66
Rheumatoid arthritis 3 | 1,191
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Aortic valve stenosis 2 | 28
Autistic Disorder 2 | 364
Bilateral fifth finger clinodactyly 2 | 110
Cognitive delay 2 | 608
Congenital Camptodactyly 2 | 40
Congenital Epicanthus 2 | 177
Craniofacial Abnormalities 2 | 151
Craniosynostosis 2 | 74
Curvature of little finger 2 | 110
Decreased projection of midface 2 | 105
Downward slant of palpebral fissure 2 | 158
Dull intelligence 2 | 645
Enophthalmos 2 | 75
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Hemochromatosis 2 | 54
Hypoplastic feet 2 | 66
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Malar flattening 2 | 129
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Midface retrusion 2 | 105
Myopia 2 | 176
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
Seizures 2 | 596
Short stature 2 | 531
Simple syndactyly of toes, first web space 2 | 23
Small head 2 | 374
Small midface 2 | 105
Stomach Neoplasms 2 | 300
Strabismus 2 | 270
Sunken eyes 2 | 63
active Crohn's disease 2 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Acquired flat foot 1 | 72
Adenocarcinoma Of Esophagus 1 | 14
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Arnold-Chiari Malformation, Type I 1 | 5
Biliary tract cancer 1 | 19
Bushy eyebrows 1 | 49
Carcinoma of pancreas 1 | 5
Carcinoma, Ductal, Breast 1 | 11
Increased risk of pancreatic cancer 1 | 9
Joint laxity 1 | 54
Liver Diseases, Parasitic 1 | 9
Malignant neoplasm of pancreas 1 | 9
Peutz-Jeghers syndrome 1 | 21
Poor speech 1 | 37
Problems speaking 1 | 37
Shallow orbits 1 | 13
Sleep Apnea, Obstructive 1 | 10
Spondylosis 1 | 16
Stomach cancer 1 | 30
Uremia 1 | 19

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 5 | 12,091
Transcription Factor 1 | 1,400

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Zinc finger FYVE domain-containing protein 16 ZFYVE16 Tbio Non-IDG -0.84581 9.36 116
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Ubiquitin-conjugating enzyme E2 D3 UBE2D3 Tbio Non-IDG -1.33082 20.0 161
Ubiquitin-conjugating enzyme E2 D1 UBE2D1 Tbio Non-IDG -2.67434 446.5 194
Ski oncogene SKI Tbio Non-IDG -1.78249 59.9 124