Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

increased mean corpuscular hem... 1 | 96

Disease

Carcinoma 5 | 11,493
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autosomal recessive predisposition 3 | 1,442
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
malignant mesothelioma 3 | 3,232
Ketoacidosis, episodic 2 | 4
Liver Cirrhosis, Experimental 2 | 769
Pick disease 2 | 1,894
Vomiting 2 | 116
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
beta-ketothiolase deficiency 2 | 13
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
osteosarcoma 2 | 7,950
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Abnormal amniotic fluid 1 | 6
Acidosis, Lactic 1 | 97
Astrocytoma, Pilocytic 1 | 3,081
Breast Neoplasms 1 | 445
Cardiomyopathy 1 | 116
Cardiomyopathy, Dilated 1 | 83
Cardiomyopathy, Hypertrophic, Familial 1 | 9
Carnitine palmitoyltransferase II deficiency 1 | 14
Chemical and Drug Induced Liver Injury 1 | 195
Chondrodysplasia punctata 1 | 41
Chromosome 3q29 microdeletion syndrome 1 | 11
Chromosome 3q29 microduplication syndrome 1 | 6
Congestive heart failure 1 | 113
Dehydration 1 | 40
Elevated hepatic transaminases 1 | 81
Failure to gain weight 1 | 365
Fatty Liver 1 | 70
Gastric antral vascular ectasia 1 | 10
Gaucher's disease 1 | 26
Generalized muscle weakness 1 | 57
Heart Diseases 1 | 43
Heart failure 1 | 162
Hepatic enzyme increased 1 | 81
Hydrops Fetalis 1 | 21
Hyperammonemia 1 | 30
Hypertrophic cardiomyopathy 20 1 | 12
Hypoketotic hypoglycemia 1 | 11
Hypoparathyroidism 1 | 41
Ketonuria 1 | 8
Kidney Failure, Chronic 1 | 46
Lactic acidemia 1 | 95
Liver Dysfunction 1 | 99
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Low Birth Weights 1 | 69
Mammary Neoplasms 1 | 425
Myalgia 1 | 54
Myoglobinuria 1 | 15
Neuropathy 1 | 261
Osteoporosis 1 | 363
Pediatric failure to thrive 1 | 365
Peripheral Neuropathy 1 | 134
Prenatal maternal abnormality 1 | 3
Respiratory Failure 1 | 104
Rhabdomyolysis 1 | 15
Seizures 1 | 596
Small for gestational age (disorder) 1 | 69
Subclinical abnormal liver function tests 1 | 81
Tachypnea 1 | 20
Transaminases increased 1 | 81
Trifunctional Protein Deficiency With Myopathy And Neuropathy 1 | 2
Very long chain acyl-CoA dehydrogenase deficiency 1 | 10
Zellweger syndrome 1 | 37
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
alpha-methylacyl-CoA racemase deficiency 1 | 9
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
colon cancer 1 | 1,478
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
fibroadenoma 1 | 559
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
nephrosclerosis 1 | 333
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 6 | 4,145

PathwayCommons: humancyc Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
3-hydroxybutyrate dehydrogenase type 2 BDH2 Tbio Enzyme -1.15003 15.8 112
D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 Tbio Enzyme -1.67412 41.4 153
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial OXCT1 Tbio Enzyme -2.36883 227.6 115
3-ketoacyl-CoA thiolase, peroxisomal ACAA1 Tbio Enzyme -2.31883 203.8 197
Acetyl-CoA acetyltransferase, mitochondrial ACAT1 Tchem Enzyme -1.85518 70.4 397
Trifunctional enzyme subunit beta, mitochondrial HADHB Tbio Enzyme -2.05645 118.4 185