Development Level

Tbio 9 | 11,445
Tchem 6 | 1,598

IMPC Phenotype

decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
increased lymphocyte cell numb... 1 | 32
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
tremors 1 | 39

Disease

Carcinoma 12 | 11,493
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
medulloblastoma, large-cell 8 | 6,241
Oculocerebrorenal syndrome 7 | 29
adult high grade glioma 7 | 3,801
glioblastoma 7 | 5,792
group 3 medulloblastoma 7 | 4,104
ovarian cancer 7 | 8,520
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
lung carcinoma 6 | 2,843
Astrocytoma, Pilocytic 5 | 3,081
Pick disease 5 | 1,894
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
psoriasis 5 | 6,694
Intellectual disability 4 | 1,016
astrocytoma 4 | 1,146
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Acquired scoliosis 3 | 281
Autosomal recessive predisposition 3 | 1,442
Cataract 3 | 297
Curvature of spine 3 | 282
Dermatologic disorders 3 | 93
Dull intelligence 3 | 645
Epilepsy 3 | 792
Frontal bossing 3 | 157
Kidney cancer 3 | 2,613
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Seizures 3 | 596
Skin Diseases 3 | 71
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
Abnormality of metabolism/homeostasis 2 | 134
Amblyopia 2 | 38
Arsenic Poisoning 2 | 62
Big calvaria 2 | 147
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Dent disease 2 | 18
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Down syndrome 2 | 499
Follicular thyroid carcinoma 2 | 14
Global developmental delay 2 | 608
Hyperkyphosis 2 | 111
Hypertension 2 | 396
Impaired cognition 2 | 96
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Juvenile polyposis syndrome 2 | 7
Kyphosis deformity of spine 2 | 114
Lens Opacities 2 | 231
Liver Cirrhosis, Experimental 2 | 769
Long narrow head 2 | 75
Long philtrum 2 | 137
Lymphatic obstruction 2 | 21
Lymphedema 2 | 42
Mammary Neoplasms 2 | 425
Mental and motor retardation 2 | 608
Mental impairment 2 | 95
Muscle hypotonia 2 | 571
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Nonmedullary Thyroid Carcinoma 2 | 10
Onset of lymphedema around puberty 2 | 21
Parkinson's disease 2 | 392
Range of joint movement increased 2 | 32
Reperfusion Injury 2 | 86
Short nose 2 | 132
Short stature 2 | 531
Small nose 2 | 132
Squamous cell carcinoma 2 | 129
Thyroid Cancer, Nonmedullary, 2 2 | 6
Turridolichocephaly 2 | 75
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
atypical teratoid/rhabdoid tumor 2 | 357
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
glioblastoma multiforme 2 | 142
invasive ductal carcinoma 2 | 2,951
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 14 | 16,678

Target Family

Enzyme 9 | 4,145
Kinase 4 | 634
Non-IDG 2 | 12,091

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 23 | 23
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptojanin-2 SYNJ2 Tbio Non-IDG -1.15573 16.3 157
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Inositol polyphosphate multikinase IPMK Tbio Kinase -1.55144 39.0 159
Inositol-trisphosphate 3-kinase B ITPKB Tchem Kinase -1.44569 29.5 168
Inositol-trisphosphate 3-kinase A ITPKA Tchem Kinase -1.42824 28.0 156
Type II inositol 1,4,5-trisphosphate 5-phosphatase INPP5B Tbio Enzyme -1.53163 29.3 109
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL1 Tchem Enzyme -2.05056 144.2 215
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 INPP5D Tbio Enzyme -2.06945 104.7 374
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.87182 73.3 126
Multiple inositol polyphosphate phosphatase 1 MINPP1 Tbio Enzyme -1.50020 32.4 219