Development Level

Tbio 4 | 11,445

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
absent startle reflex 1 | 24
hypoactivity 1 | 132

Disease

Carcinoma 3 | 11,493
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
Astrocytoma, Pilocytic 2 | 3,081
Chronic Lymphocytic Leukemia 2 | 262
Congenital clubfoot 2 | 109
EHLERS-DANLOS SYNDROME, MUSCULOCONTRACTURAL TYPE 1 2 | 2
Ehlers-Danlos syndrome 2 | 43
Ehlers-Danlos syndrome, musculocontractural type 2 | 2
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Adducted Thumbs Syndrome 1 | 1
Adducted thumb 1 | 22
Amblyopia 1 | 38
Amyotrophic lateral sclerosis 1 | 451
Anisometropia 1 | 14
Arachnodactyly 1 | 49
Astigmatism 1 | 54
Atopic dermatitis 1 | 952
Autosomal recessive predisposition 1 | 1,442
Blue sclera 1 | 32
Brachycephaly 1 | 88
Breast cancer 1 | 3,578
Broad cranium shape 1 | 88
Byzanthine arch palate 1 | 194
Clubfoot 1 | 39
Corneal edema 1 | 14
Coronary artery disease 1 | 268
Craniofacial Abnormalities 1 | 151
Crohn's disease 1 | 321
Downward slant of palpebral fissure 1 | 158
EHLERS-DANLOS SYNDROME, MUSCULOCONTRACTURAL TYPE 2 1 | 1
Ehlers-Danlos Syndrome, Musculocontractural Type, 2 1 | 1
Endometriosis 1 | 540
Female stress incontinence 1 | 7
Foramen Ovale, Patent 1 | 10
Frontal bossing 1 | 157
Generalized muscle weakness 1 | 57
Gross motor development delay 1 | 21
Hereditary spherocytosis type 2 1 | 18
Hernia, Inguinal 1 | 89
Hyperopia 1 | 70
Inadequate arch length for tooth size 1 | 45
Joint Instability 1 | 3
Kidney cancer 1 | 2,613
Liver inflammatory pseudotumor 1 | 2
Lung Neoplasms 1 | 232
Mental Depression 1 | 333
Muscle hypotonia 1 | 571
Myopia 1 | 176
Neoplasm Recurrence, Local 1 | 37
Prominent ear 1 | 56
Prostatic Neoplasms 1 | 495
Protruding ears 1 | 56
Psoriatic arthritis 1 | 86
Retinal disease 1 | 25
Retinitis pigmentosa 33 1 | 4
Telecanthus 1 | 62
Thumb in palm deformity 1 | 1
Thyroid cancer 1 | 36
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Vascular disease 1 | 319
Wide skull shape 1 | 88
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
group 4 medulloblastoma 1 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
pancreatic cancer 1 | 2,398
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 4 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 4 | 4
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dermatan-sulfate epimerase DSE Tbio Enzyme -2.57112 360.0 44
Carbohydrate sulfotransferase 15 CHST15 Tbio Enzyme -1.52053 33.4 41
Carbohydrate sulfotransferase 14 CHST14 Tbio Enzyme -2.28079 185.3 75
Uronyl 2-sulfotransferase UST Tbio Enzyme -2.27096 184.4 86