Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

Disease

Carcinoma 4 | 11,493
Mucopolysaccharidosis 4 | 26
Autosomal recessive predisposition 3 | 1,442
Cancer 2 | 2,499
Concave bridge of nose 2 | 195
Cystitis cystica 2 | 2
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Intellectual disability 2 | 1,016
Muscle hypotonia 2 | 571
Short stature 2 | 531
Abnormal CNS myelination 1 | 4
Abnormal diaphysis morphology 1 | 5
Abnormal nerve conduction velocity 1 | 4
Abnormal vertebral bodies 1 | 16
Abnormality of the acetabulum 1 | 2
Abnormality of the clavicle 1 | 14
Abnormality of the elbow 1 | 6
Abnormality of the tonsils 1 | 10
Actual Aspiration 1 | 8
Aortic Valve Insufficiency 1 | 40
Aortic valve stenosis 1 | 28
Apathy 1 | 16
Biconcave vertebral bodies 1 | 9
Broad face 1 | 7
Bushy eyebrows 1 | 49
Calvarial hyperostosis 1 | 5
Cherry red spot of the macula 1 | 7
Childhood disintegrative disease 1 | 4
Chronic diarrhea 1 | 29
Cleft uvula 1 | 27
Cloudy cornea 1 | 33
Congenital anomaly of spine 1 | 16
Congenital hypoplasia of clavicle 1 | 18
Congenital stromal corneal dystrophy 1 | 5
Corneal stromal opacities 1 | 33
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Diaphyseal thickening 1 | 11
Enlargement of calvarial bones 1 | 5
Everted lower lip vermilion 1 | 54
Exaggerated acoustic startle response 1 | 8
Exaggerated startle response 1 | 8
Fabry disease 1 | 11
Flared iliac wings 1 | 13
Generalized hirsutism 1 | 36
Gm2-ganglioside accumulation 1 | 2
Heart valve disease 1 | 39
Heparan sulfate excretion in urine 1 | 5
Hepatosplenomegaly 1 | 22
Hurler-Scheie Syndrome 1 | 1
Hyaluronidase Deficiency 1 | 1
Hyperexplexia 1 | 8
Hyperkyphosis 1 | 111
Idiopathic pulmonary arterial hypertension 1 | 40
Increased ossification of calvarial bones 1 | 5
Increased startle response 1 | 8
J-shaped hypophysial fossa 1 | 6
J-shaped sella turcica 1 | 6
Joint stiffness 1 | 84
Keratan sulfate excretion in urine 1 | 3
Knee joint valgus deformity 1 | 56
Kyphosis deformity of spine 1 | 114
Lobomycosis 1 | 2
Microdontia (disorder) 1 | 59
Mitral regurgitation, mild 1 | 32
Mitral valve insufficiency 1 | 49
Mucopolysaccharidosis I 1 | 4
Mucopolysaccharidosis V 1 | 1
Multiple vertebral anomalies 1 | 16
Narrow pelvis 1 | 6
Nasal inflammation 1 | 7
Neuronal ceroid lipofuscinosis 1 | 28
Niemann-Pick disease 1 | 14
ODONTOID HYPOPLASIA 1 | 16
Omega shaped hypophysial fossa 1 | 6
Pfaundler-Hurler Syndrome 1 | 12
Poor head control 1 | 14
Progressive neurologic deterioration 1 | 19
Protruding lower lip 1 | 54
Psychomotor degeneration 1 | 4
Pulmonary aspiration 1 | 8
Pulmonary hypertension 1 | 85
Pyramidal sign 1 | 29
Recurrent otitis media 1 | 42
Rhinitis 1 | 54
Skin Abnormalities 1 | 37
Sleep Apnea, Obstructive 1 | 10
Sleep disturbances 1 | 37
Small femoral heads 1 | 2
Spinal canal stenosis 1 | 12
Submucous cleft of hard palate 1 | 11
Submucous clefting 1 | 9
Tay-Sachs disease 1 | 6
Thick vermilion border 1 | 25
Tracheal stenosis 1 | 23
VALVULAR ABNORMALITY 1 | 12
mucopolysaccharidosis IX 1 | 2

Tissue

Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 4 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 4 | 4
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 23 | 23
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
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http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
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http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
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http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 7 | 7
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http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
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http://pathwaycommons.org/pc2/... 5 | 5
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http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hyaluronidase PH-20 SPAM1 Tbio Enzyme -2.18435 158.5 144
Alpha-L-iduronidase IDUA Tbio Enzyme -2.45679 291.5 129
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.88328 77.3 220
Beta-hexosaminidase subunit alpha HEXA Tchem Enzyme -2.83300 675.5 327