Development Level

Tbio 15 | 11,445
Tchem 4 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

increased lean body mass 3 | 172
abnormal gait 2 | 69
decreased total body fat amoun... 2 | 207
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal vocalization 1 | 21
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased mean platelet volume 1 | 25
enlarged gallbladder 1 | 2
hydrometra 1 | 53
hypoactivity 1 | 132
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
small superior vagus ganglion 1 | 74

Disease

Carcinoma 16 | 11,493
ependymoma 10 | 4,679
glioblastoma 9 | 5,792
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
Kidney cancer 7 | 2,613
lung carcinoma 7 | 2,843
adult high grade glioma 6 | 3,801
Astrocytoma, Pilocytic 5 | 3,081
Melanoma 5 | 711
atypical teratoid / rhabdoid tumor 5 | 5,112
interstitial cystitis 5 | 2,312
malignant mesothelioma 5 | 3,232
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Breast cancer 4 | 3,578
Schizophrenia 4 | 1,160
group 3 medulloblastoma 4 | 4,104
ulcerative colitis 4 | 1,819
Cancer 3 | 2,499
Skin cancer 3 | 469
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Centronuclear myopathy 2 | 27
Essential Hypertension 2 | 94
Liver cancer 2 | 604
Rheumatoid arthritis 2 | 1,191
cystic fibrosis and chronic rhinosinusitis 2 | 214
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318
Abnormality of nail of toe 1 | 11
Abnormality of the fingernails 1 | 51
Agammaglobulinemia 1 | 34
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Ankylosis 1 | 28
Asphyxia neonatorum 1 | 11
Autosomal recessive congenital ichthyosis 4B 1 | 13
Blepharitis 1 | 23
Bronchiolitis 1 | 18
Cellulitis 1 | 20
Cellulitis of eyelid 1 | 17
Cherubism 1 | 13
Chromosome 1p36 deletion syndrome 1 | 23
Chronic kidney disease stage 5 1 | 31
Congenital myopathy 1 | 16
Cryopyrin-Associated Periodic Syndromes 1 | 4
Decreased IgM 1 | 11
Edema 1 | 81
Epileptic encephalopathy 1 | 26
Erythema 1 | 58
Fibrous skin tumor of tuberous sclerosis 1 | 18
Flushing 1 | 60
Focal segmental glomerulosclerosis 1 | 10
Gastrointestinal system disease 1 | 54
Hemangiosarcoma 1 | 18
Hereditary spherocytosis type 1 1 | 23
Hypoplastic superior helix 1 | 4
Immunoglobulin A deficiency (disorder) 1 | 19
Inflammatory Bowel Diseases 1 | 35
Koilonychia 1 | 7
Leukonychia 1 | 6
Lymphoma, T-Cell, Cutaneous 1 | 22
Malocclusion 1 | 57
Multiple Endocrine Neoplasia Type 1 1 | 29
Myopathies, Structural, Congenital 1 | 15
Nail disease 1 | 9
Nephrotic Syndrome 1 | 78
Pain 1 | 103
Pneumonia, Interstitial 1 | 5
Reflex sympathetic dystrophy 1 | 7
Round face 1 | 45
Round, full face 1 | 45
Seasonal affective disorder 1 | 28
Seizures, Focal 1 | 14
Severe Dengue 1 | 3
Sezary Syndrome 1 | 27
Townes-Brocks syndrome 1 | 15
Treacher Collins syndrome 1 | 27
Type 1 diabetes mellitus 1 | 109
Uveal melanoma 1 | 20
esophageal cancer 1 | 22

Tissue

Cardiovascular System 19 | 15,192
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Blood and immune system 18 | 16,909
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393

Target Family

Enzyme 17 | 4,145
Kinase 2 | 634

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 68 | 68
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