Development Level

Tbio 50 | 10,625
Tdark 7 | 7,003
Tchem 6 | 1,890

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal bone structure 2 | 131
decreased circulating glucose ... 2 | 121
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
increased circulating total pr... 2 | 20
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased or absent threshold ... 2 | 128
increased rib number 2 | 41
preweaning lethality, incomple... 2 | 260
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal gait 1 | 51
abnormal lumbar vertebrae morp... 1 | 6
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased Ly6C high monocyte n... 1 | 18
decreased T-helper cell number 1 | 4
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
improved glucose tolerance 1 | 56
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
short snout 1 | 4
shortened RR interval 1 | 19
thrombocytosis 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 40 | 8,492
osteosarcoma 28 | 7,933
medulloblastoma, large-cell 22 | 6,234
lung cancer 21 | 4,473
psoriasis 16 | 6,685
Multiple myeloma 15 | 1,328
glioblastoma 15 | 5,572
oligodendroglioma 13 | 2,849
Breast cancer 11 | 3,099
Cancer 11 | 2,346
sonic hedgehog group medulloblastoma 11 | 1,482
astrocytic glioma 10 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
acute quadriplegic myopathy 9 | 1,157
dermatomyositis 9 | 967
ependymoma 9 | 2,514
atypical teratoid / rhabdoid tumor 8 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Waldenstrons macroglobulinemia 7 | 765
group 3 medulloblastoma 7 | 2,254
non-small cell lung cancer 7 | 2,798
pancreatic cancer 7 | 2,300
pediatric high grade glioma 7 | 2,712
pilocytic astrocytoma 7 | 3,086
Pick disease 6 | 1,893
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
juvenile dermatomyositis 6 | 1,189
malignant mesothelioma 6 | 3,163
primitive neuroectodermal tumor 6 | 3,031
Amyotrophic Lateral Sclerosis 5 | 432
Childhood Ataxia with Central Nervous System Hypomyelinization 5 | 5
Leukodystrophy 5 | 30
Leukodystrophy with vanishing white matter 5 | 5
Leukoencephalopathy With Vanishing White Matter 5 | 5
OVARIOLEUKODYSTROPHY 5 | 5
diabetes mellitus 5 | 1,663
group 4 medulloblastoma 5 | 1,875
hereditary spastic paraplegia 5 | 313
Carcinoma 4 | 2,147
Intellectual disability 4 | 573
Optic atrophy 4 | 43
adult high grade glioma 4 | 2,148
invasive ductal carcinoma 4 | 2,950
lung adenocarcinoma 4 | 2,714
posterior fossa group A ependymoma 4 | 1,511
primary pancreatic ductal adenocarcinoma 4 | 1,271
Brain disease 3 | 84
Mammary Neoplasms 3 | 410
acute myeloid leukemia 3 | 785
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
cystic fibrosis 3 | 1,670
gastric carcinoma 3 | 832
lung carcinoma 3 | 2,844
non primary Sjogren syndrome sicca 3 | 840
tuberculosis 3 | 1,563
tuberculosis and treatment for 3 months 3 | 327
tuberculosis and treatment for 6 months 3 | 686
Adenocarcinoma of lung (disorder) 2 | 48
Alzheimer's disease 2 | 644
Animal Mammary Neoplasms 2 | 136
Cutaneous anthrax 2 | 8
Epilepsy 2 | 346
HIV Infections 2 | 100
Mammary Neoplasms, Experimental 2 | 150
Microcephaly 2 | 149
Muscular atrophy 2 | 67
Neoplasm Metastasis 2 | 138
Neurodegenerative disease 2 | 383
Renal Cell Carcinoma 2 | 199
Rheumatoid Arthritis 2 | 1,171
Sertoli cell-only syndrome 2 | 36
Shwachman-Diamond syndrome 2 | 16
Stomach Neoplasms 2 | 282
Thalassemia 2 | 46
X-linked cerebral adrenoleukodystrophy 2 | 115
aldosterone-producing adenoma 2 | 664
breast carcinoma 2 | 1,614
colon cancer 2 | 1,475
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 550
interstitial cystitis 2 | 2,299
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung carcinoma 2 | 413
pancreatic carcinoma 2 | 567
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
triple-A syndrome 2 | 18
Autosomal dominant cerebellar ataxia 1 | 34
Azoospermia 1 | 89
Blepharophimosis 1 | 17
Esophageal Neoplasms 1 | 67
Freckles 1 | 6
Hemolytic anemia 1 | 70
Melanoma 1 | 261
Vaccinia 1 | 37
West Syndrome 1 | 24
fascioscapulohumeral muscular dystrophy 1 | 100

Tissue

Blood and immune system 61 | 17,995
Cardiovascular System 61 | 17,958
Digestive Tract 61 | 18,473
Endocrine System 61 | 18,512
Female tissues 61 | 18,647
Liver and Pancreas 61 | 18,136
Male tissues 61 | 17,969
Nervous System 61 | 18,561
Skin and soft tissues 61 | 18,115
Urinary Tract 61 | 18,444
Respiratory system 60 | 17,484

Target Family

Non-IDG 59 | 11,969
Enzyme 4 | 4,146

PANTHER Protein Class (3)

translation initiation factor 63 | 63
non-receptor serine/threonine ... 205 | 205
mRNA splicing factor 118 | 118
non-receptor tyrosine protein ... 97 | 97
voltage-gated potassium channe... 68 | 68
acetylcholine receptor 46 | 46
voltage-gated calcium channel 37 | 37
translation elongation factor 25 | 25
ionotropic glutamate receptor 23 | 23
mRNA polyadenylation factor 19 | 19
serine/threonine protein kinas... 19 | 19
cyclic nucleotide-gated ion ch... 18 | 18
voltage-gated sodium channel 9 | 9
translation release factor 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 TRMT6 Tdark Enzyme -0.84534 5.78 32
HBS1-like protein HBS1L Tbio Non-IDG -2.52098 316.2 144
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.18951 12.9 124
Serine-threonine kinase receptor-associated protein STRAP Tbio Enzyme -1.30190 20.6 123
Eukaryotic translation initiation factor 2A EIF2A Tbio Non-IDG -0.57210 3.87 227
Density-regulated protein DENR Tbio Non-IDG -2.07118 55.5 105
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG 0.07 0.41 76
Elongation factor G, mitochondrial GFM1 Tbio Non-IDG -2.37027 233.9 103
Mannose-1-phosphate guanyltransferase beta GMPPB Tbio Enzyme -1.14263 13.0 102
Eukaryotic translation initiation factor 5A-1 EIF5A Tbio Non-IDG -2.08738 144.6 203