Development Level

Tbio 47 | 11,445
Tdark 6 | 6,588
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
increased circulating alkaline... 3 | 122
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
increased circulating total pr... 2 | 28
increased lean body mass 2 | 172
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
corneal opacity 1 | 32
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
shortened RR interval 1 | 17
thrombocytosis 1 | 27
vertebral transformation 1 | 12

Disease

ovarian cancer 38 | 8,520
Carcinoma 34 | 11,493
osteosarcoma 25 | 7,950
medulloblastoma, large-cell 22 | 6,241
lung cancer 18 | 4,740
psoriasis 17 | 6,694
Multiple myeloma 15 | 1,332
glioblastoma 15 | 5,792
Cancer 12 | 2,499
ependymoma 12 | 4,679
group 3 medulloblastoma 12 | 4,104
oligodendroglioma 12 | 2,850
Breast cancer 11 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
astrocytic glioma 10 | 2,597
atypical teratoid / rhabdoid tumor 10 | 5,112
acute quadriplegic myopathy 9 | 1,158
dermatomyositis 9 | 966
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
pancreatic cancer 8 | 2,398
Kidney cancer 7 | 2,613
Waldenstrons macroglobulinemia 7 | 765
adult high grade glioma 7 | 3,801
diabetes mellitus 7 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Astrocytoma, Pilocytic 6 | 3,081
Pick disease 6 | 1,894
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
juvenile dermatomyositis 6 | 1,187
primitive neuroectodermal tumor 6 | 3,035
Amyotrophic lateral sclerosis 5 | 451
hereditary spastic paraplegia 5 | 318
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis 5 | 2,010
Intellectual disability 4 | 1,016
acute myeloid leukemia 4 | 783
invasive ductal carcinoma 4 | 2,951
non primary Sjogren syndrome sicca 4 | 891
pediatric high grade glioma 4 | 1,064
sonic hedgehog group medulloblastoma 4 | 467
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Epilepsy 3 | 792
Global developmental delay 3 | 608
Low intelligence 3 | 645
Mammary Neoplasms 3 | 425
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Poor school performance 3 | 645
Rheumatoid arthritis 3 | 1,191
Small head 3 | 374
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
lung carcinoma 3 | 2,843
Adenocarcinoma of lung 2 | 142
Animal Mammary Neoplasms 2 | 136
Cataract 4 multiple types 2 | 14
Congenital Epicanthus 2 | 177
Disease Models, Animal 2 | 155
Downward slant of palpebral fissure 2 | 158
Feeding difficulties 2 | 127
HIV Infections 2 | 102
Liver cancer 2 | 604
Low set ears 2 | 181
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Microcephaly 2 | 166
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Neurodegenerative disease 2 | 414
Nystagmus 2 | 317
Retinitis pigmentosa 49 2 | 14
Schizophrenia 2 | 1,160
Seizures 2 | 596
Short stature 2 | 531
Shwachman-Diamond syndrome 2 | 17
Stomach Neoplasms 2 | 300
Thalassemia 2 | 53
X-linked cerebral adrenoleukodystrophy 2 | 116
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 3 months 2 | 179
tuberculosis and treatment for 6 months 2 | 409

Tissue

Endocrine System 56 | 18,159
Male tissues 56 | 17,142
Nervous System 56 | 16,725
Blood and immune system 55 | 16,909
Cardiovascular System 55 | 15,192
Digestive Tract 55 | 17,369
Female tissues 55 | 17,400
Liver and Pancreas 55 | 16,750
Respiratory system 55 | 16,393
Skin and soft tissues 55 | 17,230
Urinary Tract 55 | 16,678

Target Family

Non-IDG 56 | 12,091
Enzyme 2 | 4,145

PANTHER Protein Class (3)

translation initiation factor 58 | 58
non-receptor serine/threonine ... 162 | 162
mRNA splicing factor 107 | 107
acetylcholine receptor 47 | 47
non-receptor tyrosine protein ... 37 | 37
voltage-gated calcium channel 23 | 23
mRNA polyadenylation factor 17 | 17
serine/threonine protein kinas... 15 | 15
voltage-gated potassium channe... 15 | 15
voltage-gated sodium channel 9 | 9
translation elongation factor 8 | 8
translation release factor 6 | 6
ionotropic glutamate receptor 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 2A EIF2A Tbio Non-IDG -0.62095 4.12 272
Eukaryotic translation initiation factor 5A-1 EIF5A Tbio Non-IDG -2.10288 142.0 231
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.20680 14.1 159
Eukaryotic translation initiation factor 3 subunit B EIF3B Tbio Non-IDG -1.83618 70.5 84
Elongation factor G, mitochondrial GFM1 Tbio Non-IDG -2.39993 250.5 121
GTP-binding protein 2 GTPBP2 Tbio Non-IDG -0.72990 5.05 143
Eukaryotic translation initiation factor 3 subunit C-like protein EIF3CL Tdark Non-IDG 0.00000 13
Clustered mitochondria protein homolog CLUH Tbio Non-IDG -0.81012 6.52 46
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363
Elongation factor-like GTPase 1 EFL1 Tbio Non-IDG -1.31803 19.5 65