Development Level

Tbio 85 | 11,178
Tdark 19 | 6,569
Tchem 3 | 1,885

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal behavior 5 | 298
hyperactivity 3 | 148
cataract 2 | 92
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased circulating creatini... 2 | 38
increased or absent threshold ... 2 | 101
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal sleep behavior 1 | 70
aorta dilation 1 | 3
decreased IgE level 1 | 6
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to t... 1 | 278
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
short tibia 1 | 97
thin ventricular wall 1 | 24

Disease

Carcinoma 65 | 11,192
ovarian cancer 60 | 8,297
osteosarcoma 53 | 7,766
psoriasis 43 | 6,514
group 3 medulloblastoma 39 | 4,002
medulloblastoma, large-cell 39 | 6,086
glioblastoma 33 | 5,635
atypical teratoid / rhabdoid tumor 30 | 4,971
ependymoma 30 | 4,559
lung cancer 30 | 4,607
malignant mesothelioma 26 | 3,135
Multiple myeloma 24 | 1,296
oligodendroglioma 23 | 2,768
primitive neuroectodermal tumor 22 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,902
Pick disease 20 | 1,856
Breast cancer 18 | 3,469
astrocytic glioma 17 | 2,530
acute quadriplegic myopathy 16 | 1,133
adult high grade glioma 16 | 3,701
Kidney cancer 15 | 2,548
dermatomyositis 15 | 941
diabetes mellitus 15 | 1,683
non-small cell lung cancer 15 | 2,799
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,204
lung adenocarcinoma 14 | 2,627
Cancer 13 | 2,388
astrocytoma 13 | 1,113
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,911
progressive supranuclear palsy 12 | 656
Waldenstrons macroglobulinemia 11 | 742
breast carcinoma 11 | 1,589
invasive ductal carcinoma 11 | 2,867
subependymal giant cell astrocytoma 11 | 2,230
pancreatic cancer 10 | 2,322
Astrocytoma, Pilocytic 9 | 3,006
Intellectual disability 9 | 998
Gaucher disease type 1 8 | 177
group 4 medulloblastoma 8 | 1,806
Dull intelligence 7 | 634
Low intelligence 7 | 634
Mental Retardation 7 | 634
Mental deficiency 7 | 634
Poor school performance 7 | 634
Rheumatoid arthritis 7 | 1,156
hepatocellular carcinoma 7 | 536
lung carcinoma 7 | 2,755
non primary Sjogren syndrome sicca 7 | 861
pituitary cancer 7 | 1,915
Conductive hearing loss 6 | 122
Glaucoma 6 | 232
HIV Infections 6 | 94
Obesity 6 | 655
Schizophrenia 6 | 1,136
aldosterone-producing adenoma 6 | 646
colon cancer 6 | 1,428
sonic hedgehog group medulloblastoma 6 | 459
Abnormality of retinal pigmentation 5 | 109
Abnormality of the retinal vasculature 5 | 58
Anteverted nostril 5 | 186
Atypical scarring of skin 5 | 61
Blind Vision 5 | 110
Blindness, Legal 5 | 109
Broad flat nasal bridge 5 | 232
Cataract 5 | 290
Congenital anomaly of testis 5 | 51
Congenital hypoplasia of penis 5 | 168
Electroretinogram abnormal 5 | 94
Hyperinsulinism 5 | 128
Hypogonadism 5 | 169
Keratoconus 5 | 111
Lens Opacities 5 | 227
Male infertility 5 | 199
Nasal bridge wide 5 | 232
Night blindness, progressive 5 | 50
Nystagmus 5 | 309
Ophthalmoplegia 5 | 105
Optic Atrophy 5 | 239
Photodysphoria 5 | 117
Photophobia 5 | 117
Polycystic ovary syndrome 5 | 348
Retinal pigment epithelial abnormality 5 | 109
Retinitis Pigmentosa 5 | 223
Sensorineural Hearing Loss (disorder) 5 | 281
acute myeloid leukemia 5 | 760
interstitial lung disease 5 | 287
nasopharyngeal carcinoma 5 | 1,024
spina bifida 5 | 1,053
tuberculosis 5 | 1,963
Acquired metabolic disease 4 | 329
Alzheimer's disease 4 | 640
Amyotrophic lateral sclerosis 4 | 437
adrenocortical carcinoma 4 | 1,385
atypical teratoid/rhabdoid tumor 4 | 349
ductal carcinoma in situ 4 | 1,686
juvenile dermatomyositis 4 | 1,147
pancreatic carcinoma 4 | 555
pediatric high grade glioma 4 | 1,035
tuberculosis and treatment for 6 months 4 | 399

Tissue

Endocrine System 106 | 18,159
Female tissues 102 | 17,400
Respiratory system 102 | 16,393
Urinary Tract 102 | 16,678
Blood and immune system 101 | 16,909
Digestive Tract 101 | 17,369
Liver and Pancreas 101 | 16,750
Male tissues 101 | 17,142
Nervous System 100 | 16,725
Skin and soft tissues 100 | 17,230
Cardiovascular System 98 | 15,192

Target Family

Non-IDG 105 | 12,091
Enzyme 2 | 4,145

PANTHER Protein Class (3)

mRNA splicing factor 107 | 107
non-receptor serine/threonine ... 157 | 157
translation initiation factor 58 | 58
acetylcholine receptor 47 | 47
non-receptor tyrosine protein ... 37 | 37
voltage-gated calcium channel 23 | 23
mRNA polyadenylation factor 17 | 17
serine/threonine protein kinas... 15 | 15
voltage-gated potassium channe... 15 | 15
voltage-gated sodium channel 9 | 9
translation elongation factor 8 | 8
translation release factor 6 | 6
ionotropic glutamate receptor 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Poly(rC)-binding protein 2 PCBP2 Tbio Non-IDG -1.90173 82.3 183
Serine/arginine-rich splicing factor 7 SRSF7 Tbio Non-IDG -1.19691 12.9 177
RNA-binding motif protein, Y chromosome, family 1 member F/J RBMY1J Tdark Non-IDG 0.31 0.53 49
Splicing factor 3B subunit 3 SF3B3 Tchem Non-IDG -1.28872 19.5 222
Pre-mRNA-processing factor 17 CDC40 Tbio Non-IDG -1.37680 24.3 102
RNA-binding motif protein, X-linked-like-3 RBMXL3 Tdark Non-IDG 0.78 0.08 0
Ubiquitin carboxyl-terminal hydrolase 43 USP43 Tdark Enzyme 0.48 0.33 121
Ubiquitin carboxyl-terminal hydrolase 31 USP31 Tbio Enzyme 0.48 0.00000 42
Tuftelin-interacting protein 11 TFIP11 Tbio Non-IDG -1.75990 66.6 84
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149