Development Level

Tbio 16 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
increased fasted circulating g... 2 | 76
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
decreased bone mineral density 1 | 126
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
increased bone mineral density 1 | 72
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
osteosarcoma 9 | 7,950
group 3 medulloblastoma 8 | 4,104
medulloblastoma, large-cell 8 | 6,241
lung cancer 7 | 4,740
ovarian cancer 7 | 8,520
glioblastoma 6 | 5,792
atypical teratoid / rhabdoid tumor 5 | 5,112
Breast cancer 4 | 3,578
astrocytic glioma 4 | 2,597
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
spina bifida 3 | 1,074
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Cerebral atrophy 2 | 178
Cognitive delay 2 | 608
Crohn's disease 2 | 321
Cryptorchidism 2 | 296
Dilated ventricles (finding) 2 | 121
Disease Progression 2 | 136
Global developmental delay 2 | 608
Mental and motor retardation 2 | 608
Neurodegenerative disease 2 | 414
Pontocerebellar hypoplasia 2 | 36
Small head 2 | 374
Stomach Neoplasms 2 | 300
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
Abnormal blistering of the skin 1 | 54
Abnormal pigmentation 1 | 25
Adult onset 1 | 82
Alopecia 1 | 115
Antisocial personality disorder 1 | 9
Bipolar I disorder 1 | 23
Blister of skin 1 | 54
Blood Coagulation Disorders 1 | 42
Cataract 7 1 | 32
Cellular immunodeficiency 1 | 17
Chagas disease 1 | 39
Coagulation abnormalities 1 | 27
Cortical gyral simplification 1 | 19
Decreased platelet count 1 | 111
Delayed myelination 1 | 22
Delusional disorder 1 | 13
Dental caries 1 | 164
Dyskeratosis congenita 1 | 24
Dystrophia unguium 1 | 53
Encephalopathies 1 | 43
Esophageal Stenosis 1 | 15
Esotropia 1 | 31
Frequent fractures 1 | 53
Gaucher disease type 1 1 | 180
Gingival Diseases 1 | 19
Hemorrhagic Disorders 1 | 30
Hyperhidrosis disorder 1 | 81
Hypodontia 1 | 81
Immunologic Deficiency Syndromes 1 | 113
Increased fracture rate 1 | 53
Increased sweating 1 | 81
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Leukoplakia, Oral 1 | 20
Long eyelashes 1 | 37
Lymphoid leukemia 1 | 160
Malabsorption 1 | 82
Neutrophil abnormality 1 | 20
Periodontal Diseases 1 | 21
Poor growth 1 | 114
Prion disease 1 | 16
Recurrent respiratory infections 1 | 141
Skin Ulcer 1 | 48
Skin bulla 1 | 54
Sweating 1 | 81
Telangiectasia of the skin 1 | 39
Thin upper lip vermilion 1 | 67
Thrombocytopenia 1 | 197
Tracheoesophageal Fistula 1 | 36
Varying degree of multiple fractures 1 | 53
Very poor growth 1 | 114
hypopigmented skin patch 1 | 59
interstitial lung disease 1 | 298
limb girdle muscular dystrophy 2B 1 | 40
permanent atrial fibrillation 1 | 45
sarcoidosis 1 | 370

Tissue

Endocrine System 17 | 18,159
Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Cardiovascular System 15 | 15,192
Urinary Tract 15 | 16,678

Target Family

Non-IDG 10 | 12,091
Enzyme 7 | 4,145

PANTHER Protein Class (3)

mRNA polyadenylation factor 17 | 17
non-receptor serine/threonine ... 162 | 162
mRNA splicing factor 107 | 107
translation initiation factor 58 | 58
acetylcholine receptor 47 | 47
non-receptor tyrosine protein ... 37 | 37
voltage-gated calcium channel 23 | 23
serine/threonine protein kinas... 15 | 15
voltage-gated potassium channe... 15 | 15
voltage-gated sodium channel 9 | 9
translation elongation factor 8 | 8
translation release factor 6 | 6
ionotropic glutamate receptor 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
Poly(A) polymerase beta PAPOLB Tbio Enzyme -1.66566 44.9 59
Poly(A) polymerase gamma PAPOLG Tbio Enzyme -2.00403 100.4 97
Poly(A)-specific ribonuclease PNLDC1 PNLDC1 Tbio Enzyme -0.61101 2.88 60
Poly(A) polymerase alpha PAPOLA Tbio Enzyme -0.76388 5.75 90
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.23906 178.8 222
Polyribonucleotide 5'-hydroxyl-kinase Clp1 CLP1 Tbio Enzyme -1.48371 28.0 159
Cytoplasmic polyadenylation element-binding protein 4 CPEB4 Tbio Non-IDG -1.53041 33.8 114
Integrator complex subunit 11 INTS11 Tbio Non-IDG -0.83885 6.42 114
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.34679 21.2 88