Development Level

Tclin 28 | 602
Tchem 17 | 1,890
Tdark 1 | 7,003

Collection

Eligible Ion Channel Proteins 22 | 117

IMPC Term

enlarged heart 2 | 111
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal testis morphology 1 | 30
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased grip strength 1 | 123
increased body length 1 | 20
increased bone mineral density 1 | 52
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small testis 1 | 37

Disease

General anesthesia 23 | 53
Epilepsy 21 | 346
medulloblastoma, large-cell 19 | 6,234
psoriasis 19 | 6,685
Nicotine dependence 17 | 53
Anxiety 16 | 24
Insomnia 16 | 20
Tonic-clonic epilepsy 16 | 47
atypical teratoid / rhabdoid tumor 15 | 4,369
glioblastoma 15 | 5,572
Alcohol dependence 14 | 107
Autistic Disorder 14 | 320
Sedation as Adjunct to Anesthesia 13 | 15
Carcinoma 12 | 2,147
pilocytic astrocytoma 12 | 3,086
primitive neuroectodermal tumor 12 | 3,031
Irritable bowel syndrome 11 | 59
oligodendroglioma 11 | 2,849
lung carcinoma 10 | 2,844
pediatric high grade glioma 9 | 2,712
Alcohol withdrawal delirium 8 | 9
Alcohol withdrawal syndrome 8 | 9
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Chemotherapy-induced nausea and vomiting 8 | 18
Induce Anterograde Amnesia 8 | 9
Local anesthesia 8 | 40
Panic disorder 8 | 55
Preoperative Anxiety 8 | 9
Schizophrenia 8 | 501
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Spasticity 8 | 26
Status Epilepticus 8 | 85
Tetanus 8 | 66
ependymoma 8 | 2,514
medulloblastoma 8 | 1,524
osteosarcoma 8 | 7,933
Anxiety associated with Menopause 7 | 7
Conscious sedation 7 | 10
Feeling agitated 7 | 7
Generalized anxiety disorder 7 | 29
Mixed anxiety and depressive disorder 7 | 10
Muscle relaxation, function 7 | 8
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic ulcer 7 | 22
Pre-Op Apprehension 7 | 10
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
adult high grade glioma 7 | 2,148
lung cancer 7 | 4,466
ovarian cancer 7 | 8,484
subependymal giant cell astrocytoma 7 | 2,287
Frontal lobe epilepsy 6 | 8
Initial insomnia 6 | 8
Pain with Tension and Anxiety 6 | 6
Pick disease 6 | 1,893
Smoking cessation assistance 6 | 8
astrocytoma 6 | 1,493
pituitary cancer 6 | 1,972
Breast cancer 5 | 3,094
Cocaine dependence 5 | 24
Congenital myasthenic syndrome 5 | 28
Diabetic gastroparesis 5 | 7
Disorders of initiating and maintaining sleep 5 | 8
Gastroesophageal reflux disease 5 | 37
Gastrointestinal Radiography Adjunct 5 | 11
Intubation of gastrointestinal tract 5 | 7
Multiple pterygium syndrome 5 | 17
Niacin deficiency 5 | 5
Nicotine Withdrawal Symptoms 5 | 5
Pellagra 5 | 25
Prevention of Post-Operative Nausea and Vomiting 5 | 14
Schizoaffective disorder 5 | 33
Seizures 5 | 95
Skeletal Muscle Relaxation for Endotracheal Intubation 5 | 5
Skeletal Muscle Relaxation for Endotracheal Intubation in C-Section 5 | 5
TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) 5 | 12
astrocytic glioma 5 | 2,241
posterior fossa group A ependymoma 5 | 1,511
Absence seizure 4 | 12
Alcoholic Intoxication, Chronic 4 | 41
Atonic seizure 4 | 4
Bipolar Disorder 4 | 266
Cerebral ischemia 4 | 12
Heroin dependence 4 | 30
Lennox-Gastaut syndrome 4 | 34
Myasthenic syndrome, congenital, postsynaptic slow-channel 4 | 4
Myoclonic seizure 4 | 4
Neuropathy 4 | 210
Seizure disorder 4 | 4
Substance Withdrawal Syndrome 4 | 52
Tetanus Adjunct Treatment 4 | 8
group 4 medulloblastoma 4 | 1,875
pterygium 4 | 74
substance-related disorder 4 | 105
Chronic obstructive pulmonary disease 3 | 146
Parkinson's disease 3 | 364
active Crohn's disease 3 | 918

Tissue

Female tissues 46 | 18,647
Digestive Tract 45 | 18,473
Endocrine System 45 | 18,512
Nervous System 45 | 18,561
Urinary Tract 45 | 18,444
Liver and Pancreas 44 | 18,136
Skin and soft tissues 44 | 18,115
Blood and immune system 41 | 17,995
Respiratory system 41 | 17,484
Cardiovascular System 40 | 17,958
Male tissues 40 | 17,969

Target Family

Ion Channel 46 | 341

PANTHER Protein Class (3)

acetylcholine receptor 46 | 46
non-receptor serine/threonine ... 205 | 205
mRNA splicing factor 118 | 118
non-receptor tyrosine protein ... 97 | 97
voltage-gated potassium channe... 68 | 68
translation initiation factor 63 | 63
voltage-gated calcium channel 37 | 37
translation elongation factor 25 | 25
ionotropic glutamate receptor 23 | 23
mRNA polyadenylation factor 19 | 19
serine/threonine protein kinas... 19 | 19
cyclic nucleotide-gated ion ch... 18 | 18
voltage-gated sodium channel 9 | 9
translation release factor 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.23749 17.4 128
Glycine receptor subunit beta GLRB Tclin Ion Channel -1.15613 15.9 85
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.37968 2392.4 232
Acetylcholine receptor subunit beta CHRNB1 Tclin Ion Channel -1.24555 17.5 166
Neuronal acetylcholine receptor subunit alpha-7 CHRFAM7A Tchem Ion Channel -1.90534 84.1 211
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.59352 37.2 293
Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1 Tclin Ion Channel -1.76425 55.7 254