Development Level
Tbio | 61 | 11,445 | |
Tdark | 9 | 6,588 | |
Tchem | 6 | 1,598 |
IMPC Phenotype
preweaning lethality, complete... | 6 | 979 | |
abnormal bone structure | 3 | 187 | |
increased circulating alkaline... | 3 | 122 | |
preweaning lethality, incomple... | 3 | 499 | |
decreased bone mineral content | 2 | 151 | |
decreased grip strength | 2 | 116 | |
decreased total body fat amoun... | 2 | 207 | |
embryonic lethality prior to o... | 2 | 239 | |
hypoactivity | 2 | 132 | |
increased circulating HDL chol... | 2 | 80 | |
increased circulating choleste... | 2 | 66 | |
increased circulating free fat... | 2 | 20 | |
increased circulating total pr... | 2 | 28 | |
increased lean body mass | 2 | 172 | |
abnormal cornea morphology | 1 | 31 | |
abnormal cranium morphology | 1 | 36 | |
abnormal embryo size | 1 | 220 | |
abnormal gait | 1 | 69 | |
abnormal retina morphology | 1 | 71 | |
abnormal sleep behavior | 1 | 70 | |
abnormal snout morphology | 1 | 23 | |
abnormal spleen morphology | 1 | 55 | |
corneal opacity | 1 | 32 | |
decreased body length | 1 | 101 | |
decreased bone mineral density | 1 | 126 | |
decreased circulating HDL chol... | 1 | 68 | |
decreased circulating LDL chol... | 1 | 38 | |
decreased circulating alanine ... | 1 | 47 | |
decreased circulating aspartat... | 1 | 34 | |
decreased circulating calcium ... | 1 | 36 | |
decreased circulating chloride... | 1 | 30 | |
decreased circulating choleste... | 1 | 93 | |
decreased circulating glucose ... | 1 | 126 | |
decreased fasted circulating g... | 1 | 65 | |
decreased lactate dehydrogenas... | 1 | 16 | |
decreased leukocyte cell numbe... | 1 | 73 | |
decreased lymphocyte cell numb... | 1 | 83 | |
decreased neutrophil cell numb... | 1 | 42 | |
decreased prepulse inhibition | 1 | 82 | |
enlarged lymph nodes | 1 | 37 | |
hemorrhage | 1 | 23 | |
hyperactivity | 1 | 148 | |
impaired pupillary reflex | 1 | 26 | |
improved glucose tolerance | 1 | 79 | |
increased circulating calcium ... | 1 | 34 | |
increased circulating glucose ... | 1 | 24 | |
increased circulating iron lev... | 1 | 30 | |
increased circulating serum al... | 1 | 22 | |
increased mean corpuscular hem... | 1 | 96 | |
increased mean platelet volume | 1 | 45 | |
increased or absent threshold ... | 1 | 101 | |
increased vertical activity | 1 | 24 | |
male infertility | 1 | 123 | |
prenatal lethality prior to he... | 1 | 87 | |
shortened RR interval | 1 | 17 | |
thrombocytosis | 1 | 27 | |
vertebral transformation | 1 | 12 |
Disease
Tissue
Endocrine System | 74 | 18,159 | |
Male tissues | 74 | 17,142 | |
Nervous System | 74 | 16,725 | |
Blood and immune system | 73 | 16,909 | |
Cardiovascular System | 73 | 15,192 | |
Digestive Tract | 73 | 17,369 | |
Female tissues | 73 | 17,400 | |
Liver and Pancreas | 73 | 16,750 | |
Respiratory system | 73 | 16,393 | |
Skin and soft tissues | 73 | 17,230 | |
Urinary Tract | 73 | 16,678 |
Target Family
Non-IDG | 67 | 12,091 | |
Enzyme | 6 | 4,145 | |
Transporter | 3 | 473 |
PANTHER Protein Class (2)
translation factor | 76 | 76 | |
protein kinase | 257 | 257 | |
serine protease | 175 | 175 | |
ribosomal protein | 152 | 152 | |
cysteine protease | 142 | 142 | |
metalloprotease | 135 | 135 | |
mRNA processing factor | 122 | 122 | |
calmodulin | 113 | 113 | |
chromatin/chromatin-binding pr... | 106 | 106 | |
serine protease inhibitor | 94 | 94 | |
non-motor actin binding protei... | 90 | 90 | |
homeodomain transcription fact... | 88 | 88 | |
small GTPase | 81 | 81 | |
guanyl-nucleotide exchange fac... | 77 | 77 | |
ligand-gated ion channel | 69 | 69 | |
microtubule binding motor prot... | 62 | 62 | |
histone | 61 | 61 | |
non-motor microtubule binding ... | 57 | 57 | |
kinase activator | 55 | 55 | |
chemokine | 48 | 48 | |
DNA-directed RNA polymerase | 46 | 46 | |
ribonucleoprotein | 44 | 44 | |
heterotrimeric G-protein | 43 | 43 | |
protein phosphatase | 41 | 41 | |
nucleotide kinase | 37 | 37 | |
RNA helicase | 35 | 35 | |
phosphatase inhibitor | 34 | 34 | |
nucleotide phosphatase | 33 | 33 | |
actin and actin related protei... | 31 | 31 | |
kinase inhibitor | 31 | 31 | |
phospholipase | 30 | 30 | |
ATP synthase | 28 | 28 | |
DNA helicase | 28 | 28 | |
actin binding motor protein | 27 | 27 | |
C2H2 zinc finger transcription... | 25 | 25 | |
calcium channel | 23 | 23 | |
DNA-directed DNA polymerase | 22 | 22 | |
endoribonuclease | 22 | 22 | |
tubulin | 22 | 22 | |
aspartic protease | 21 | 21 | |
exoribonuclease | 21 | 21 | |
type I cytokine receptor | 20 | 20 | |
anion channel | 19 | 19 | |
carbohydrate kinase | 17 | 17 | |
endodeoxyribonuclease | 15 | 15 | |
intermediate filament binding ... | 15 | 15 | |
neuropeptide | 15 | 15 | |
potassium channel | 15 | 15 | |
DNA methyltransferase | 12 | 12 | |
type II cytokine receptor | 12 | 12 | |
RNA methyltransferase | 11 | 11 | |
damaged DNA-binding protein | 11 | 11 | |
tumor necrosis factor family m... | 11 | 11 | |
sodium channel | 9 | 9 | |
neurotrophic factor | 8 | 8 | |
replication origin binding pro... | 8 | 8 | |
winged helix/forkhead transcri... | 8 | 8 | |
carbohydrate phosphatase | 6 | 6 | |
amino acid kinase | 5 | 5 | |
guanylate cyclase | 5 | 5 | |
DNA topoisomerase | 4 | 4 | |
interleukin superfamily | 4 | 4 | |
CREB-related transcription fac... | 3 | 3 | |
C4 zinc finger nuclear recepto... | 2 | 2 | |
DNA photolyase | 2 | 2 | |
Lambda repressor-like transcri... | 2 | 2 | |
cysteine protease inhibitor | 2 | 2 | |
tumor necrosis factor receptor | 2 | 2 | |
DNA glycosylase | 1 | 1 | |
DNA polymerase processivity fa... | 1 | 1 | |
centromere DNA-binding protein | 1 | 1 | |
exodeoxyribonuclease | 1 | 1 | |
phosphatase activator | 1 | 1 | |
primase | 1 | 1 | |
reverse transcriptase | 1 | 1 |
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