Development Level

Tbio 68 | 11,445
Tdark 7 | 6,588
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
decreased body length 3 | 101
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
short tibia 3 | 97
abnormal cranium morphology 2 | 36
decreased circulating iron lev... 2 | 32
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
increased circulating alkaline... 2 | 122
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal joint morphology 1 | 23
abnormal locomotor activation 1 | 16
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
enlarged heart 1 | 210
enlarged kidney 1 | 14
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating glucose ... 1 | 24
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small spleen 1 | 19
thrombocytopenia 1 | 56

Disease

Carcinoma 47 | 11,493
ovarian cancer 47 | 8,520
glioblastoma 45 | 5,792
osteosarcoma 41 | 7,950
medulloblastoma, large-cell 40 | 6,241
psoriasis 36 | 6,694
atypical teratoid / rhabdoid tumor 32 | 5,112
ependymoma 32 | 4,679
lung cancer 31 | 4,740
adult high grade glioma 29 | 3,801
Breast cancer 26 | 3,578
Astrocytoma, Pilocytic 24 | 3,081
Cancer 24 | 2,499
astrocytic glioma 24 | 2,597
group 3 medulloblastoma 24 | 4,104
invasive ductal carcinoma 23 | 2,951
lung carcinoma 23 | 2,843
malignant mesothelioma 22 | 3,232
oligodendroglioma 22 | 2,850
primitive neuroectodermal tumor 22 | 3,035
subependymal giant cell astrocytoma 22 | 2,287
group 4 medulloblastoma 18 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung adenocarcinoma 17 | 2,716
pancreatic cancer 16 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
non-small cell lung cancer 15 | 2,890
Multiple myeloma 14 | 1,332
Pick disease 14 | 1,894
ductal carcinoma in situ 13 | 1,745
primary pancreatic ductal adenocarcinoma 13 | 1,109
Kidney cancer 12 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
juvenile dermatomyositis 12 | 1,187
acute quadriplegic myopathy 11 | 1,158
interstitial cystitis 11 | 2,312
cutaneous lupus erythematosus 10 | 1,057
cystic fibrosis 10 | 1,696
pediatric high grade glioma 10 | 1,064
Blepharoptosis 9 | 231
Muscle hypotonia 9 | 571
ulcerative colitis 9 | 1,819
Rheumatoid arthritis 8 | 1,191
astrocytoma 8 | 1,146
breast carcinoma 8 | 1,638
dermatomyositis 8 | 966
Hemangioma 7 | 69
Melanoma 7 | 711
Short stature 7 | 531
Strabismus 7 | 270
Waldenstrons macroglobulinemia 7 | 765
pituitary cancer 7 | 1,972
primary Sjogren syndrome 7 | 735
Abnormal dermatoglyphic pattern 6 | 24
Byzanthine arch palate 6 | 194
Intellectual disability 6 | 1,016
Joint hyperflexibility 6 | 78
Parkinson's disease 6 | 392
Schizophrenia 6 | 1,160
colon cancer 6 | 1,478
diabetes mellitus 6 | 1,728
gastric cancer 6 | 459
nasopharyngeal carcinoma 6 | 1,058
progressive supranuclear palsy 6 | 676
tuberculosis 6 | 2,010
Acquired scoliosis 5 | 281
Alzheimer's disease 5 | 658
Aortic coarctation 5 | 30
Curvature of spine 5 | 282
Down syndrome 5 | 499
Dull intelligence 5 | 645
Failure to gain weight 5 | 365
Juvenile Myelomonocytic Leukemia 5 | 21
Leukemia, Myelomonocytic, Juvenile 5 | 20
Low intelligence 5 | 645
Low set ears 5 | 181
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Noonan syndrome 5 | 34
Pediatric failure to thrive 5 | 365
Poor school performance 5 | 645
Stomach Neoplasms 5 | 300
active ulcerative colitis 5 | 764
pancreatic carcinoma 5 | 562
spina bifida 5 | 1,074
Amyotrophic lateral sclerosis 4 | 451
Attention deficit hyperactivity disorder 4 | 278
Congenital Epicanthus 4 | 177
Delayed bone age 4 | 136
Epilepsy 4 | 792
Heart disease 4 | 306
Hyperreflexia 4 | 209
Seizures 4 | 596
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 559
hepatocellular carcinoma 4 | 547
hereditary spastic paraplegia 4 | 318
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962

Tissue

Endocrine System 79 | 18,159
Female tissues 78 | 17,400
Nervous System 78 | 16,725
Skin and soft tissues 78 | 17,230
Blood and immune system 77 | 16,909
Digestive Tract 77 | 17,369
Male tissues 77 | 17,142
Liver and Pancreas 76 | 16,750
Respiratory system 76 | 16,393
Urinary Tract 76 | 16,678
Cardiovascular System 74 | 15,192

Target Family

Enzyme 47 | 4,145
Non-IDG 34 | 12,091

PANTHER Protein Class (2)

small GTPase 81 | 81
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
Importin-9 IPO9 Tbio Non-IDG -1.14983 12.2 108
Importin-11 IPO11 Tbio Non-IDG -0.74763 5.44 154
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Transmembrane protein 250 TMEM250 Tdark Non-IDG 0.00000 1.00 3
Septin-9 SEPT9 Tbio Non-IDG -2.20898 161.9 130
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Septin-4 SEPT4 Tbio Non-IDG -2.38258 232.7 201