Development Level

Tbio 70 | 11,445
Tdark 17 | 6,588
Tchem 5 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
enlarged heart 2 | 210
short tibia 2 | 97
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal lymph node morphology 1 | 3
abnormal spleen morphology 1 | 55
absent vibrissae 1 | 12
cataract 1 | 92
decreased body temperature 1 | 2
decreased heart rate 1 | 18
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
head bobbing 1 | 5
hypoactivity 1 | 132
impaired righting response 1 | 26
increased circulating sodium l... 1 | 71
increased heart left ventricle... 1 | 4
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24

Disease

Carcinoma 64 | 11,493
psoriasis 43 | 6,694
ovarian cancer 35 | 8,520
non-small cell lung cancer 29 | 2,890
osteosarcoma 28 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
lung cancer 26 | 4,740
lung carcinoma 26 | 2,843
ependymoma 25 | 4,679
medulloblastoma, large-cell 25 | 6,241
glioblastoma 24 | 5,792
Kidney cancer 23 | 2,613
interstitial cystitis 23 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
Breast cancer 22 | 3,578
pancreatic cancer 22 | 2,398
atypical teratoid / rhabdoid tumor 21 | 5,112
cystic fibrosis 21 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
malignant mesothelioma 20 | 3,232
ulcerative colitis 20 | 1,819
Cancer 19 | 2,499
adult high grade glioma 19 | 3,801
lung adenocarcinoma 19 | 2,716
Astrocytoma, Pilocytic 18 | 3,081
invasive ductal carcinoma 18 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Autosomal recessive predisposition 16 | 1,442
gastric carcinoma 16 | 807
primary pancreatic ductal adenocarcinoma 16 | 1,109
Atopic dermatitis 13 | 952
astrocytic glioma 13 | 2,597
colon cancer 13 | 1,478
pituitary cancer 12 | 1,972
primitive neuroectodermal tumor 12 | 3,035
tuberculosis 12 | 2,010
subependymal giant cell astrocytoma 11 | 2,287
Melanoma 10 | 711
adrenocortical carcinoma 10 | 1,428
breast carcinoma 10 | 1,638
ductal carcinoma in situ 10 | 1,745
group 3 medulloblastoma 10 | 4,104
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
Schizophrenia 9 | 1,160
Skin cancer 9 | 469
diabetes mellitus 9 | 1,728
esophageal adenocarcinoma 9 | 737
nasopharyngeal carcinoma 9 | 1,058
oligodendroglioma 9 | 2,850
Cerebrovascular disease 8 | 238
Disseminated intravascular coagulation 8 | 38
Duchenne muscular dystrophy 8 | 601
Weill-Marchesani syndrome 8 | 14
cutaneous lupus erythematosus 8 | 1,057
fibroadenoma 8 | 559
juvenile dermatomyositis 8 | 1,187
Acquired metabolic disease 7 | 336
Alzheimer's disease 7 | 658
Liver Cirrhosis 7 | 181
Liver disease 7 | 237
Atherosclerosis 6 | 291
Bipolar Disorder 6 | 666
Carcinoma, Hepatocellular 6 | 228
Chronic obstructive pulmonary disease 6 | 184
Coronary artery disease 6 | 268
Liver carcinoma 6 | 240
Rheumatoid arthritis 6 | 1,191
Vascular disease 6 | 319
active ulcerative colitis 6 | 764
acute quadriplegic myopathy 6 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
group 4 medulloblastoma 6 | 1,855
posterior fossa group A ependymoma 6 | 468
sonic hedgehog group medulloblastoma 6 | 467
spina bifida 6 | 1,074
Anemia 5 | 365
Arthritis 5 | 290
Breast Neoplasms 5 | 445
Chemical and Drug Induced Liver Injury 5 | 195
Diarrhea 5 | 253
Hypertension 5 | 396
Liver cancer 5 | 604
Lung disease 5 | 142
Mammary Neoplasms 5 | 425
Nephrotic Syndrome 5 | 78
Systemic lupus erythematosus 5 | 194
non diabetic and post-ischemic heart failure 5 | 200
Cholestasis 4 | 155
Contact Dermatitis 4 | 81
Dementia 4 | 175
Endometriosis 4 | 540
Multiple Sclerosis 4 | 540
Polycystic ovary syndrome 4 | 360
Prostatic Neoplasms 4 | 495
active Crohn's disease 4 | 922
aldosterone-producing adenoma 4 | 665
atypical teratoid/rhabdoid tumor 4 | 357
head and neck cancer 4 | 271
primary Sjogren syndrome 4 | 735

Tissue

Endocrine System 87 | 18,159
Digestive Tract 86 | 17,369
Male tissues 86 | 17,142
Female tissues 85 | 17,400
Skin and soft tissues 83 | 17,230
Urinary Tract 81 | 16,678
Liver and Pancreas 80 | 16,750
Blood and immune system 79 | 16,909
Respiratory system 77 | 16,393
Nervous System 71 | 16,725
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 69 | 12,091
Enzyme 25 | 4,145

PANTHER Protein Class (2)

serine protease inhibitor 94 | 94
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1-antichymotrypsin SERPINA3 Tbio Non-IDG -2.94780 812.7 276
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
A disintegrin and metalloproteinase with thrombospondin motifs 8 ADAMTS8 Tbio Enzyme -1.14483 14.5 153
Serpin A9 SERPINA9 Tbio Non-IDG -1.94929 88.4 132
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Leukocyte elastase inhibitor SERPINB1 Tbio Enzyme -2.55345 336.3 370
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.44459 279.8 227
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
A disintegrin and metalloproteinase with thrombospondin motifs 14 ADAMTS14 Tbio Enzyme -0.89572 7.58 29