Development Level

Tbio 135 | 10,625
Tdark 71 | 7,003
Tchem 68 | 1,890
Tclin 11 | 602

IMPC Term

preweaning lethality, complete... 9 | 633
preweaning lethality, incomple... 5 | 260
abnormal embryo size 4 | 112
abnormal behavior 3 | 226
decreased body length 3 | 108
decreased circulating choleste... 3 | 85
decreased lean body mass 3 | 195
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
increased circulating alkaline... 3 | 119
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 93
short tibia 3 | 82
abnormal QRS complex 2 | 25
abnormal bone mineralization 2 | 55
abnormal limb morphology 2 | 7
abnormal skin appearance 2 | 8
abnormal sleep behavior 2 | 63
abnormal tail morphology 2 | 17
convulsive seizures 2 | 11
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased cervical vertebrae n... 2 | 12
decreased circulating HDL chol... 2 | 77
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased leukocyte cell numbe... 2 | 54
decreased prepulse inhibition 2 | 52
decreased respiratory quotient 2 | 12
embryonic growth retardation 2 | 28
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
hypoactivity 2 | 89
increased erythrocyte cell num... 2 | 26
increased or absent threshold ... 2 | 128
increased rib number 2 | 41
increased sacral vertebrae num... 2 | 62
oligodactyly 2 | 14
small thymus 2 | 11
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal embryo turning 1 | 15
abnormal facial morphology 1 | 9
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
cleft palate 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C high monocyte n... 1 | 18
decreased T cell number 1 | 31
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased pulmonary respirator... 1 | 4
decreased threshold for audito... 1 | 32
enlarged spleen 1 | 26
enlarged stomach 1 | 2
hemorrhage 1 | 12
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
lethargy 1 | 5
shortened PQ interval 1 | 6
small adrenal glands 1 | 15
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

psoriasis 126 | 6,685
ovarian cancer 107 | 8,484
osteosarcoma 104 | 7,933
glioblastoma 80 | 5,572
medulloblastoma, large-cell 78 | 6,234
lung cancer 76 | 4,466
pancreatic cancer 73 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 72 | 3,289
lung carcinoma 68 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 67 | 2,988
lung adenocarcinoma 67 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 62 | 2,956
Cancer 56 | 2,346
atypical teratoid / rhabdoid tumor 56 | 4,369
invasive ductal carcinoma 55 | 2,950
pilocytic astrocytoma 54 | 3,086
interstitial cystitis 53 | 2,299
non-small cell lung cancer 53 | 2,798
cystic fibrosis 51 | 1,665
malignant mesothelioma 51 | 3,162
Carcinoma 48 | 2,147
ulcerative colitis 47 | 2,087
Breast cancer 46 | 3,094
pancreatic ductal adenocarcinoma liver metastasis 44 | 1,795
oligodendroglioma 42 | 2,849
adult high grade glioma 41 | 2,148
primitive neuroectodermal tumor 41 | 3,031
pediatric high grade glioma 40 | 2,712
diabetes mellitus 39 | 1,663
subependymal giant cell astrocytoma 38 | 2,287
pituitary cancer 36 | 1,972
colon cancer 34 | 1,475
tuberculosis 33 | 1,557
Atopic dermatitis 32 | 944
posterior fossa group A ependymoma 30 | 1,511
breast carcinoma 29 | 1,614
group 4 medulloblastoma 29 | 1,875
cutaneous lupus erythematosus 28 | 1,056
ductal carcinoma in situ 28 | 1,745
primary pancreatic ductal adenocarcinoma 28 | 1,271
Pick disease 27 | 1,893
ependymoma 27 | 2,514
nasopharyngeal carcinoma 26 | 1,056
esophageal adenocarcinoma 25 | 737
group 3 medulloblastoma 25 | 2,254
gastric carcinoma 24 | 832
adrenocortical carcinoma 23 | 1,427
Kidney disease 22 | 396
posterior fossa group B ependymoma 22 | 1,530
astrocytic glioma 21 | 2,241
medulloblastoma 21 | 1,524
Rheumatoid Arthritis 20 | 1,160
astrocytoma 20 | 1,493
sonic hedgehog group medulloblastoma 20 | 1,482
mucosa-associated lymphoid tissue lymphoma 19 | 480
Alzheimer's disease 18 | 644
Cerebrovascular disease 18 | 231
Obesity 18 | 616
Duchenne muscular dystrophy 17 | 602
active Crohn's disease 17 | 918
dermatomyositis 17 | 933
spina bifida 17 | 1,064
Atherosclerosis 16 | 275
Hypertension 16 | 287
atypical teratoid/rhabdoid tumor 16 | 1,095
fibroadenoma 16 | 557
juvenile dermatomyositis 16 | 1,189
active ulcerative colitis 15 | 477
primary Sjogren syndrome 15 | 789
Anemia 14 | 252
Pancreatitis 14 | 97
Prostatic Neoplasms 14 | 471
Vascular disease 14 | 281
non-inflammatory breast cancer 14 | 208
Autistic Disorder 13 | 320
Coronary artery disease 12 | 240
Thrombocytopenia 12 | 105
Thrombophilia 12 | 36
non primary Sjogren syndrome sicca 12 | 840
non-small cell lung carcinoma 12 | 413
pancreatic carcinoma 12 | 567
Age related macular degeneration 11 | 84
Down syndrome 11 | 548
Multiple Sclerosis 11 | 498
acute quadriplegic myopathy 11 | 1,157
chronic rhinosinusitis 11 | 512
Hypertensive disease 10 | 193
IGA Glomerulonephritis 10 | 454
Myocardial Infarction 10 | 126
limb girdle muscular dystrophy 2A 10 | 156
Asthma 9 | 349
Crohn's disease 9 | 304
Endometriosis 9 | 535
Multiple myeloma 9 | 1,327
Schizophrenia 9 | 501
Waldenstrons macroglobulinemia 9 | 765
acute myeloid leukemia 9 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
nephrosclerosis 9 | 329
urothelial carcinoma 9 | 318

Tissue

Nervous System 274 | 18,561
Digestive Tract 272 | 18,473
Endocrine System 272 | 18,512
Female tissues 272 | 18,647
Liver and Pancreas 272 | 18,136
Male tissues 272 | 17,969
Urinary Tract 272 | 18,444
Cardiovascular System 271 | 17,958
Blood and immune system 270 | 17,995
Skin and soft tissues 269 | 18,115
Respiratory system 267 | 17,484

Target Family

Enzyme 168 | 4,146
Non-IDG 111 | 11,971
Transcription Factor 6 | 1,400

PANTHER Protein Class (2)

serine protease 285 | 285
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Transmembrane protease serine 6 TMPRSS6 Tchem Enzyme -1.99222 118.1 102
Seizure protein 6 homolog SEZ6 Tdark Non-IDG -0.87986 8.64 27
Coagulation factor XI F11 Tchem Enzyme -2.65863 487.3 216
Plasma kallikrein KLKB1 Tclin Enzyme -2.88472 708.0 231
Tolloid-like protein 1 TLL1 Tbio Non-IDG -1.40066 23.4 60
Transmembrane gamma-carboxyglutamic acid protein 3 PRRG3 Tdark Non-IDG -0.21639 1.71 76
Transmembrane gamma-carboxyglutamic acid protein 4 PRRG4 Tdark Non-IDG -0.29670 2.24 21
Ovochymase-2 OVCH2 Tdark Enzyme 0.00000 0
Transmembrane protease serine 7 TMPRSS7 Tdark Enzyme 0.24 0.97 63