Development Level

Tbio 143 | 10,625
Tdark 69 | 7,003
Tchem 4 | 1,890

IMPC Term

preweaning lethality, complete... 8 | 633
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 4 | 187
decreased circulating chloride... 3 | 32
decreased total body fat amoun... 3 | 186
abnormal embryo size 2 | 112
abnormal neural tube closure 2 | 37
decreased body weight 2 | 174
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
abnormal allantois morphology 1 | 3
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal incisor morphology 1 | 3
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal mandible morphology 1 | 2
abnormal midbrain development 1 | 22
abnormal neural tube morpholog... 1 | 8
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal tail bud morphology 1 | 6
abnormal tooth morphology 1 | 24
abnormal vertebral arch morpho... 1 | 9
absent pinna reflex 1 | 21
decreased CD11b-low dendritic ... 1 | 3
decreased NK T cell number 1 | 28
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased follicular B cell nu... 1 | 4
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased CD11b-high dendritic... 1 | 5
increased KLRG1-positive NK ce... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased heart weight 1 | 37
increased marginal zone B cell... 1 | 3
increased mean platelet volume 1 | 19
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 100 | 8,484
osteosarcoma 69 | 7,933
lung cancer 67 | 4,466
medulloblastoma, large-cell 59 | 6,234
psoriasis 45 | 6,685
Multiple myeloma 44 | 1,327
glioblastoma 41 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
atypical teratoid / rhabdoid tumor 35 | 4,369
diabetes mellitus 31 | 1,663
Breast cancer 29 | 3,094
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,795
acute quadriplegic myopathy 25 | 1,157
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
malignant mesothelioma 25 | 3,162
primitive neuroectodermal tumor 25 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
Waldenstrons macroglobulinemia 22 | 765
group 3 medulloblastoma 22 | 2,254
sonic hedgehog group medulloblastoma 22 | 1,482
Diamond-Blackfan anemia 21 | 28
ependymoma 21 | 2,514
non primary Sjogren syndrome sicca 21 | 840
oligodendroglioma 20 | 2,849
invasive ductal carcinoma 19 | 2,950
pediatric high grade glioma 19 | 2,712
astrocytic glioma 18 | 2,241
non-small cell lung cancer 18 | 2,798
acute myeloid leukemia 17 | 780
cystic fibrosis 17 | 1,665
lung adenocarcinoma 17 | 2,713
pilocytic astrocytoma 17 | 3,086
subependymal giant cell astrocytoma 17 | 2,287
Pick disease 16 | 1,893
adult high grade glioma 16 | 2,148
medulloblastoma 16 | 1,524
astrocytoma 14 | 1,493
juvenile dermatomyositis 13 | 1,189
Anemia, Diamond-Blackfan 12 | 15
Cancer 12 | 2,346
Mammary Neoplasms 12 | 410
breast carcinoma 12 | 1,614
colon cancer 12 | 1,475
posterior fossa group A ependymoma 11 | 1,511
Anemia 10 | 252
Disease Progression 10 | 125
Stomach Neoplasms 10 | 282
adrenocortical carcinoma 10 | 1,427
dermatomyositis 10 | 933
lung carcinoma 10 | 2,844
Duchenne muscular dystrophy 9 | 602
Rheumatoid Arthritis 9 | 1,160
atypical teratoid/rhabdoid tumor 9 | 1,095
inflammatory breast cancer 9 | 404
posterior fossa group B ependymoma 9 | 1,530
pancreatic cancer 8 | 2,300
ulcerative colitis 8 | 2,087
group 4 medulloblastoma 7 | 1,875
mucosa-associated lymphoid tissue lymphoma 7 | 480
primary pancreatic ductal adenocarcinoma 7 | 1,271
tuberculosis and treatment for 6 months 7 | 686
Bowen-Conradi syndrome 6 | 16
cutaneous lupus erythematosus 6 | 1,056
hepatocellular carcinoma 6 | 532
pituitary cancer 6 | 1,972
Animal Mammary Neoplasms 5 | 136
Mammary Neoplasms, Experimental 5 | 150
Prostatic Neoplasms 5 | 471
ductal carcinoma in situ 5 | 1,745
glioblastoma multiforme 5 | 347
progressive supranuclear palsy 5 | 674
tuberculosis 5 | 1,557
Amyotrophic Lateral Sclerosis 4 | 431
IGA Glomerulonephritis 4 | 454
Multiple Sclerosis 4 | 498
Obesity 4 | 616
active Crohn's disease 4 | 918
esophageal adenocarcinoma 4 | 737
hereditary spastic paraplegia 4 | 313
interstitial cystitis 4 | 2,299
limb girdle muscular dystrophy 2A 4 | 156
nasopharyngeal carcinoma 4 | 1,056
non diabetic and post-ischemic heart failure 4 | 200
primary Sjogren syndrome 4 | 789
spina bifida 4 | 1,064
Atopic dermatitis 3 | 944
Becker muscular dystrophy 3 | 187
Cerebrovascular disease 3 | 231
Down syndrome 3 | 548
Liver carcinoma 3 | 217
Melanoma 3 | 261
Metabolic syndrome X 3 | 155
Osteoporosis 3 | 257
Parkinson Disease 3 | 102
Weight Gain 3 | 87
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
gastric cancer 3 | 430
non-inflammatory breast cancer 3 | 208

Tissue

Blood and immune system 211 | 17,995
Male tissues 211 | 17,969
Cardiovascular System 210 | 17,958
Digestive Tract 210 | 18,473
Endocrine System 210 | 18,512
Female tissues 210 | 18,647
Liver and Pancreas 210 | 18,136
Nervous System 210 | 18,561
Urinary Tract 210 | 18,444
Respiratory system 209 | 17,484
Skin and soft tissues 207 | 18,115

Target Family

Non-IDG 164 | 11,971
Transporter 47 | 473
Enzyme 5 | 4,146

PANTHER Protein Class (2)

ribosomal protein 216 | 216
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial 2-oxodicarboxylate carrier SLC25A21 Tbio Transporter -0.46900 2.68 102
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
60S ribosomal protein L7a RPL7A Tbio Non-IDG -1.66015 45.9 60
39S ribosomal protein L19, mitochondrial MRPL19 Tbio Non-IDG -0.91149 8.14 108
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39563 24.2 45
U3 small nucleolar RNA-associated protein 6 homolog UTP6 Tbio Non-IDG -1.00948 10.4 87
U3 small nucleolar RNA-associated protein 14 homolog A UTP14A Tdark Non-IDG -0.37115 2.10 96
Mitochondrial brown fat uncoupling protein 1 UCP1 Tbio Non-IDG -3.04555 1148.0 252
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150