Development Level

Tbio 104 | 11,651
Tdark 47 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 14 | 979
abnormal behavior 4 | 298
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal embryo size 2 | 220
decreased mean corpuscular hem... 2 | 31
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
hypoactivity 2 | 132
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38

Disease

ovarian cancer 77 | 8,520
lung cancer 55 | 4,740
osteosarcoma 42 | 7,950
Multiple myeloma 36 | 1,332
medulloblastoma, large-cell 35 | 6,241
Carcinoma 33 | 11,493
psoriasis 31 | 6,694
group 3 medulloblastoma 28 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
Breast cancer 24 | 3,578
atypical teratoid / rhabdoid tumor 23 | 5,112
diabetes mellitus 23 | 1,728
glioblastoma 23 | 5,792
Diamond-Blackfan anemia 22 | 31
acute quadriplegic myopathy 20 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Waldenstrons macroglobulinemia 17 | 765
ependymoma 16 | 4,679
non primary Sjogren syndrome sicca 16 | 891
malignant mesothelioma 15 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Anemia 14 | 365
cystic fibrosis 14 | 1,696
invasive ductal carcinoma 14 | 2,951
acute myeloid leukemia 13 | 783
Cleft Palate 12 | 271
Uranostaphyloschisis 12 | 167
non-small cell lung cancer 12 | 2,890
Abnormality of the urinary system 11 | 21
Anemia, Diamond-Blackfan 11 | 16
Anemia, Macrocytic 11 | 18
Cardiac Arrhythmia 11 | 103
Cardiac conduction abnormalities 11 | 78
Conduction disorder of the heart 11 | 79
Delayed Puberty 11 | 97
EKG abnormalities 11 | 78
Electrocardiogram abnormal 11 | 81
Electrocardiogram change 11 | 78
Fatigue 11 | 182
Hand deformities 11 | 32
Intermittent migraine headaches 11 | 68
Migraine Disorders 11 | 76
Pallor 11 | 40
adult high grade glioma 11 | 3,801
genital abnormal 11 | 17
lung adenocarcinoma 11 | 2,716
oligodendroglioma 11 | 2,850
primitive neuroectodermal tumor 11 | 3,035
reproductive system abnormality 11 | 17
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
astrocytic glioma 10 | 2,597
Disease Progression 9 | 136
Stomach Neoplasms 9 | 300
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
subependymal giant cell astrocytoma 9 | 2,287
Adenocarcinoma of lung 8 | 142
Disease Models, Animal 8 | 155
juvenile dermatomyositis 8 | 1,187
sonic hedgehog group medulloblastoma 8 | 467
Cancer 7 | 2,499
Pick disease 7 | 1,894
dermatomyositis 7 | 966
pediatric high grade glioma 7 | 1,064
Astrocytoma, Pilocytic 6 | 3,081
Short stature 6 | 531
breast carcinoma 6 | 1,638
mucosa-associated lymphoid tissue lymphoma 6 | 484
Bowen-Conradi syndrome 5 | 16
Hypoplastic mandible condyle 5 | 275
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Osteoporosis 5 | 363
Reticulocytopenia 5 | 10
Small head 5 | 374
primary pancreatic ductal adenocarcinoma 5 | 1,109
Amyotrophic lateral sclerosis 4 | 451
Autosomal recessive Robinow syndrome 4 | 27
Autosomal recessive predisposition 4 | 1,442
Duchenne muscular dystrophy 4 | 601
Hemoglobin low 4 | 124
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Prostatic Neoplasms 4 | 495
adrenocortical carcinoma 4 | 1,428
cutaneous lupus erythematosus 4 | 1,057
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
inflammatory breast cancer 4 | 286
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676
tuberculosis and treatment for 6 months 4 | 409
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
nasopharyngeal carcinoma 3 | 1,058
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 146 | 18,159
Blood and immune system 145 | 16,909
Digestive Tract 145 | 17,369
Male tissues 145 | 17,142
Skin and soft tissues 145 | 17,230
Cardiovascular System 144 | 15,192
Female tissues 144 | 17,400
Liver and Pancreas 144 | 16,750
Nervous System 144 | 16,725
Respiratory system 144 | 16,393
Urinary Tract 144 | 16,678

Target Family

Non-IDG 148 | 12,091
Enzyme 4 | 4,145

PANTHER Protein Class (2)

ribosomal protein 152 | 152
protein kinase 257 | 257
serine protease 175 | 175
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
28S ribosomal protein S14, mitochondrial MRPS14 Tdark Non-IDG 0.30 0.11 22
39S ribosomal protein L42, mitochondrial MRPL42 Tdark Non-IDG 0.02 0.40 139
H/ACA ribonucleoprotein complex subunit 1 GAR1 Tbio Non-IDG -0.33131 2.70 86
39S ribosomal protein S18a, mitochondrial MRPS18A Tdark Non-IDG 0.32 0.72 57
60S ribosomal protein L7-like 1 RPL7L1 Tdark Non-IDG 0.41 0.39 57
39S ribosomal protein L16, mitochondrial MRPL16 Tdark Non-IDG -0.22185 1.67 71
Heterogeneous nuclear ribonucleoprotein H HNRNPH1 Tbio Non-IDG -1.71562 50.9 205
60S ribosomal protein L6 RPL6 Tbio Non-IDG -1.58528 37.8 68
39S ribosomal protein L35, mitochondrial MRPL35 Tdark Non-IDG 0.85 0.29 21
60S ribosomal protein L7a RPL7A Tbio Non-IDG -1.68610 47.6 62