Development Level

Tclin 38 | 602
Tbio 17 | 10,625
Tchem 7 | 1,890
Tdark 6 | 7,003

Collection

Eligible Ion Channel Proteins 21 | 117

IMPC Term

abnormal behavior 2 | 226
increased mean corpuscular vol... 2 | 91
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
decreased circulating serum al... 1 | 79
enlarged epididymis 1 | 27
hyperactivity 1 | 108
increased caudal vertebrae num... 1 | 8
increased circulating magnesiu... 1 | 10
increased exploration in new e... 1 | 56
increased vertical activity 1 | 18
kyphosis 1 | 5

Disease

medulloblastoma, large-cell 34 | 6,234
Multiple Sclerosis 33 | 498
Eaton-Lambert syndrome 32 | 40
glioblastoma 30 | 5,572
pilocytic astrocytoma 25 | 3,086
atypical teratoid / rhabdoid tumor 24 | 4,369
primitive neuroectodermal tumor 24 | 3,031
oligodendroglioma 21 | 2,849
osteosarcoma 21 | 7,933
pediatric high grade glioma 20 | 2,712
Carcinoma 19 | 2,147
astrocytic glioma 18 | 2,241
ependymoma 17 | 2,514
ovarian cancer 17 | 8,484
lung cancer 16 | 4,466
psoriasis 16 | 6,685
Long QT syndrome 15 | 52
malignant mesothelioma 15 | 3,162
medulloblastoma 15 | 1,524
Epilepsy 14 | 346
pituitary cancer 13 | 1,972
subependymal giant cell astrocytoma 13 | 2,287
adult high grade glioma 12 | 2,148
lung carcinoma 12 | 2,844
posterior fossa group A ependymoma 10 | 1,511
adrenocortical carcinoma 9 | 1,427
cystic fibrosis 9 | 1,665
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
Episodic ataxia 8 | 17
colon cancer 8 | 1,475
group 3 medulloblastoma 8 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung adenocarcinoma 8 | 2,713
Atrial Fibrillation 7 | 110
Breast cancer 7 | 3,094
group 4 medulloblastoma 7 | 1,875
interstitial cystitis 7 | 2,299
non-small cell lung cancer 7 | 2,798
posterior fossa group B ependymoma 7 | 1,530
Intellectual disability 6 | 573
Pick disease 6 | 1,893
astrocytoma 6 | 1,493
sonic hedgehog group medulloblastoma 6 | 1,482
Bipolar Disorder 5 | 266
General anesthesia 5 | 53
active Crohn's disease 5 | 918
atypical teratoid/rhabdoid tumor 5 | 1,095
invasive ductal carcinoma 5 | 2,950
pancreatic cancer 5 | 2,300
progressive supranuclear palsy 5 | 674
ulcerative colitis 5 | 2,087
Partial Epilepsy Treatment Adjunct 4 | 16
Type 2 diabetes mellitus 4 | 189
active ulcerative colitis 4 | 477
breast carcinoma 4 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
primary pancreatic ductal adenocarcinoma 4 | 1,271
tuberculosis 4 | 1,557
Amyotrophic Lateral Sclerosis 3 | 431
Benign neonatal seizures 3 | 4
Brugada syndrome 3 | 26
Cerebellar Ataxia 3 | 72
Dentin sensitivity 3 | 14
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Diaphragmatic Hernia 3 | 40
Heart disease 3 | 279
Hypertension 3 | 287
Hypokalemic periodic paralysis 3 | 13
Neurodegenerative disease 3 | 383
Spinocerebellar ataxia type 13 3 | 5
acute quadriplegic myopathy 3 | 1,157
diabetes mellitus 3 | 1,663
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 832
nasopharyngeal carcinoma 3 | 1,056
Autosomal dominant cerebellar ataxia 2 | 34
Brain Ischemia 2 | 87
Brugada Syndrome (disorder) 2 | 15
Chronic obstructive pulmonary disease 2 | 146
Cognitive disorder 2 | 44
Conn's syndrome 2 | 22
Developmental Disabilities 2 | 20
Early infantile epileptic encephalopathy with suppression bursts 2 | 18
Familial atrial fibrillation 2 | 16
Fragile X syndrome 2 | 31
Heart conduction disease 2 | 65
Hyperaldosteronism 2 | 27
Migraine 2 | 79
Migraine Disorders 2 | 26
Osteoporosis 2 | 257
Parkinson's disease 2 | 364
Schizophrenia 2 | 501
Seizure Adverse Event 2 | 19
Sensorineural hearing loss 2 | 107
Status Epilepticus 2 | 85
aldosterone-producing adenoma 2 | 664
fibroadenoma 2 | 557
spina bifida 2 | 1,064
substance-related disorder 2 | 105

Tissue

Nervous System 68 | 18,561
Endocrine System 67 | 18,512
Digestive Tract 66 | 18,473
Female tissues 66 | 18,647
Urinary Tract 66 | 18,444
Cardiovascular System 65 | 17,958
Liver and Pancreas 65 | 18,136
Blood and immune system 64 | 17,995
Male tissues 64 | 17,969
Skin and soft tissues 64 | 18,115
Respiratory system 63 | 17,484

Target Family

Ion Channel 62 | 341
Enzyme 3 | 4,146
Non-IDG 3 | 11,971

PANTHER Protein Class (2)

potassium channel 68 | 68
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Aflatoxin B1 aldehyde reductase member 4 AKR7L Tdark Enzyme 15.0 0
Potassium voltage-gated channel subfamily A member 3 KCNA3 Tclin Ion Channel -2.64735 493.0 284
Potassium voltage-gated channel subfamily C member 1 KCNC1 Tclin Ion Channel -2.42317 260.8 283
Voltage-gated potassium channel subunit beta-3 KCNAB3 Tdark Ion Channel -0.68945 4.88 108
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.61411 39.3 71
Potassium voltage-gated channel subfamily A member 7 KCNA7 Tclin Ion Channel -0.87674 7.71 52
Potassium voltage-gated channel subfamily A member 1 KCNA1 Tclin Ion Channel -2.56457 365.5 298
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.30673 205.2 153
BTB/POZ domain-containing protein KCTD3 KCTD3 Tdark Non-IDG -0.00074 1.05 86