Development Level

Tbio 20 | 11,445
Tdark 14 | 6,588

IMPC Phenotype

decreased body weight 1 | 161
decreased lean body mass 1 | 135
hyperactivity 1 | 148
increased leukocyte cell numbe... 1 | 47
increased total body fat amoun... 1 | 134

Disease

medulloblastoma, large-cell 15 | 6,241
ovarian cancer 14 | 8,520
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 12 | 5,792
adult high grade glioma 11 | 3,801
group 3 medulloblastoma 11 | 4,104
Carcinoma 10 | 11,493
ependymoma 10 | 4,679
psoriasis 10 | 6,694
Breast cancer 9 | 3,578
oligodendroglioma 9 | 2,850
Multiple myeloma 8 | 1,332
subependymal giant cell astrocytoma 8 | 2,287
astrocytic glioma 7 | 2,597
primitive neuroectodermal tumor 7 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
osteosarcoma 6 | 7,950
Waldenstrons macroglobulinemia 5 | 765
colon cancer 5 | 1,478
malignant mesothelioma 5 | 3,232
Gonadoblastoma 4 | 34
Pick disease 4 | 1,894
dermatomyositis 4 | 966
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
Amyotrophic lateral sclerosis 3 | 451
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Male infertility 3 | 206
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
gastric carcinoma 3 | 807
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
Alcoholic Intoxication, Chronic 2 | 289
Cancer 2 | 2,499
Chronic obstructive pulmonary disease 2 | 184
Congenital stationary night blindness 2 | 29
Hypogonadism 2 | 173
Kidney cancer 2 | 2,613
Schizophrenia 2 | 1,160
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
tuberculosis 2 | 2,010
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of the voice 1 | 46
Adenocarcinoma of lung 1 | 142
Alzheimer's disease 1 | 658
Anemia 1 | 365
Carcinoma, Hepatocellular 1 | 228
Cardiac Arrhythmia 1 | 103
Cardiovascular system disease 1 | 246
Death in early childhood 1 | 82
Death in infancy 1 | 82
Decreased tendon reflex 1 | 122
Dermatitis 1 | 157
Disease Models, Animal 1 | 155
Disorder of eye 1 | 27
Emery-Dreifuss muscular dystrophy 1 | 23
Eye Abnormalities 1 | 35
Gastroesophageal reflux disease 1 | 110
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Heartburn 1 | 78
Huntington's disease 1 | 76
Hypertension 1 | 396
Kidney disease 1 | 430
Liver Cirrhosis, Experimental 1 | 769
Liver carcinoma 1 | 240
Lung disease 1 | 142
Melanoma 1 | 711
Multiple Sclerosis 1 | 540
Neoplasm Invasiveness 1 | 161
Ophthalmoplegia 1 | 106
Pain disorder 1 | 15
Parkinson's disease 1 | 392
Poor growth 1 | 114
Skin atrophy 1 | 16
Toxic encephalopathy 1 | 141
Very poor growth 1 | 114
X-linked cerebral adrenoleukodystrophy 1 | 116
atypical teratoid/rhabdoid tumor 1 | 357
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
posterior fossa group B ependymoma 1 | 416
tuberculosis and treatment for 6 months 1 | 409

Tissue

Endocrine System 28 | 18,159
Digestive Tract 22 | 17,369
Liver and Pancreas 22 | 16,750
Skin and soft tissues 22 | 17,230
Blood and immune system 21 | 16,909
Male tissues 21 | 17,142
Cardiovascular System 20 | 15,192
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Female tissues 19 | 17,400
Urinary Tract 19 | 16,678

Target Family

Non-IDG 26 | 12,091
Enzyme 8 | 4,145

PANTHER Protein Class (2)

phosphatase inhibitor 34 | 34
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

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