Development Level

Tbio 22 | 11,445
Tdark 7 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

decreased body weight 2 | 161
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
increased circulating HDL chol... 2 | 80
increased mean corpuscular hem... 2 | 36
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal pharyngeal arch morph... 1 | 8
aorta dilation 1 | 3
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
increased T cell number 1 | 6
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

ovarian cancer 21 | 8,520
Carcinoma 19 | 11,493
osteosarcoma 17 | 7,950
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
psoriasis 11 | 6,694
ependymoma 9 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
adult high grade glioma 8 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Breast cancer 7 | 3,578
Autosomal recessive predisposition 6 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
Astrocytoma, Pilocytic 5 | 3,081
Neurodegenerative disease 5 | 414
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
interstitial cystitis 5 | 2,312
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676
Bipolar Disorder 3 | 666
Cancer 3 | 2,499
Down syndrome 3 | 499
Endometriosis 3 | 540
Intellectual disability 3 | 1,016
Multiple myeloma 3 | 1,332
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Neuropathy 3 | 261
Optic Atrophy 3 | 242
Schizophrenia 3 | 1,160
Skeletal muscle atrophy 3 | 139
Waldenstrons macroglobulinemia 3 | 765
hereditary spastic paraplegia 3 | 318
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
muscle degeneration 3 | 139
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Anemia 2 | 365
Arterial calcification of infancy 2 | 6
Ataxia with oculomotor apraxia type 1 2 | 5
Attention deficit hyperactivity disorder 2 | 278
Babinski Reflex 2 | 100
Contracture 2 | 96
Contracture of joint 2 | 93
Crohn's disease 2 | 321
Dull intelligence 2 | 645
Epilepsy 2 | 792
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Gait abnormality 2 | 135
Hepatitis 2 | 67
Hypoplasia of corpus callosum 2 | 90
Kidney cancer 2 | 2,613
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Motor delay 2 | 147
Myopia 2 | 176
No development of motor milestones 2 | 147
Obesity 2 | 678
Poor school performance 2 | 645
Recurrence 2 | 33
Reflex, Deep Tendon, Absent 2 | 92
active Crohn's disease 2 | 922
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
periodontitis 2 | 293
spina bifida 2 | 1,074
Amyotrophic lateral sclerosis type 8 1 | 10
Gait, Drop Foot 1 | 24
Lipoid nephrosis 1 | 4

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Urinary Tract 32 | 16,678
Male tissues 31 | 17,142
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Nervous System 30 | 16,725
Cardiovascular System 29 | 15,192

Target Family

Enzyme 25 | 4,145
Non-IDG 8 | 12,091

PANTHER Protein Class (2)

nucleotide phosphatase 33 | 33
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1 Tchem Enzyme -2.74480 552.8 275
Ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 Tchem Enzyme -2.68249 518.8 505
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 ENPP2 Tchem Enzyme -2.62921 463.2 377
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 ENPP3 Tbio Enzyme -2.63069 396.7 315
Histidine triad nucleotide-binding protein 1 HINT1 Tbio Non-IDG -2.59024 379.5 178
Inosine triphosphate pyrophosphatase ITPA Tbio Enzyme -2.54659 339.8 215
Ectonucleoside triphosphate diphosphohydrolase 2 ENTPD2 Tchem Enzyme -2.37613 245.8 150
Cytosolic purine 5'-nucleotidase NT5C2 Tbio Enzyme -2.24348 166.8 144
Mitofusin-1 MFN1 Tbio Non-IDG -2.10909 104.1 0