Development Level

Tbio 132 | 10,625
Tdark 28 | 7,003
Tchem 1 | 1,890

IMPC Term

preweaning lethality, complete... 9 | 633
increased or absent threshold ... 5 | 128
decreased lean body mass 4 | 195
decreased total body fat amoun... 4 | 186
embryonic lethality prior to t... 4 | 187
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
abnormal embryo size 3 | 112
abnormal lens morphology 3 | 73
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased circulating HDL chol... 3 | 77
decreased circulating choleste... 3 | 85
decreased circulating insulin ... 3 | 75
increased circulating alkaline... 3 | 119
increased grip strength 3 | 83
increased lean body mass 3 | 107
short tibia 3 | 82
abnormal behavioral response t... 2 | 52
abnormal cranium morphology 2 | 32
abnormal eye morphology 2 | 38
abnormal maxilla morphology 2 | 16
abnormal skin coloration 2 | 18
abnormal sleep behavior 2 | 63
decreased blood urea nitrogen ... 2 | 31
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating glucose ... 2 | 121
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
decreased mean corpuscular vol... 2 | 50
decreased rib number 2 | 59
increased circulating chloride... 2 | 43
increased circulating phosphat... 2 | 24
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
prenatal lethality prior to he... 2 | 64
abnormal coat/hair pigmentatio... 1 | 54
abnormal craniofacial morpholo... 1 | 12
abnormal embryo turning 1 | 15
abnormal eye size 1 | 11
abnormal heart left ventricle ... 1 | 20
abnormal joint morphology 1 | 14
abnormal motor capabilities/co... 1 | 4
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 11
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal thoracic vertebrae mo... 1 | 16
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
absent pinna reflex 1 | 21
cataract 1 | 26
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T-helper cell number 1 | 4
decreased alpha-beta T cell nu... 1 | 12
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
hypoactivity 1 | 89
increased CD4-positive, CD25-p... 1 | 18
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
microphthalmia 1 | 15
pallor 1 | 13
short snout 1 | 4
short tail 1 | 4
sparse hair 1 | 6
straub tail 1 | 26
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

ovarian cancer 87 | 8,484
glioblastoma 80 | 5,572
medulloblastoma, large-cell 80 | 6,234
psoriasis 74 | 6,685
osteosarcoma 73 | 7,933
atypical teratoid / rhabdoid tumor 57 | 4,369
pancreatic cancer 56 | 2,300
pilocytic astrocytoma 54 | 3,086
lung cancer 53 | 4,466
intraductal papillary-mucinous carcinoma (IPMC) 50 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,289
pediatric high grade glioma 50 | 2,712
primitive neuroectodermal tumor 49 | 3,031
invasive ductal carcinoma 47 | 2,950
lung carcinoma 45 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,956
Breast cancer 43 | 3,094
oligodendroglioma 41 | 2,849
subependymal giant cell astrocytoma 41 | 2,287
Carcinoma 40 | 2,147
ependymoma 40 | 2,514
non-small cell lung cancer 40 | 2,798
lung adenocarcinoma 38 | 2,713
malignant mesothelioma 38 | 3,162
primary pancreatic ductal adenocarcinoma 37 | 1,271
colon cancer 33 | 1,475
breast carcinoma 31 | 1,614
ductal carcinoma in situ 31 | 1,745
Pick disease 27 | 1,893
acute quadriplegic myopathy 27 | 1,157
adrenocortical carcinoma 26 | 1,427
Duchenne muscular dystrophy 24 | 602
interstitial cystitis 24 | 2,299
spina bifida 24 | 1,064
tuberculosis 24 | 1,557
astrocytoma 23 | 1,493
cystic fibrosis 23 | 1,665
medulloblastoma 23 | 1,524
pituitary cancer 23 | 1,972
sonic hedgehog group medulloblastoma 23 | 1,482
astrocytic glioma 22 | 2,241
group 4 medulloblastoma 22 | 1,875
posterior fossa group A ependymoma 21 | 1,511
ulcerative colitis 20 | 2,087
dermatomyositis 19 | 933
gastric carcinoma 19 | 832
juvenile dermatomyositis 19 | 1,189
Rheumatoid Arthritis 18 | 1,160
atypical teratoid/rhabdoid tumor 18 | 1,095
nasopharyngeal carcinoma 17 | 1,056
esophageal adenocarcinoma 16 | 737
group 3 medulloblastoma 16 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 499
adult high grade glioma 14 | 2,148
Atopic dermatitis 13 | 944
cutaneous lupus erythematosus 13 | 1,056
posterior fossa group B ependymoma 13 | 1,530
progressive supranuclear palsy 13 | 674
Alzheimer's disease 12 | 644
Down syndrome 12 | 548
diabetes mellitus 12 | 1,663
pancreatic carcinoma 12 | 567
Cancer 11 | 2,346
Multiple myeloma 10 | 1,327
acute myeloid leukemia 10 | 780
aldosterone-producing adenoma 10 | 664
fibroadenoma 10 | 557
Cardiomyopathy 9 | 110
Polycystic Ovary Syndrome 9 | 332
Waldenstrons macroglobulinemia 9 | 765
mucosa-associated lymphoid tissue lymphoma 9 | 480
primary Sjogren syndrome 9 | 789
Chondrosarcoma 8 | 24
active ulcerative colitis 8 | 477
chronic rhinosinusitis 8 | 512
hereditary spastic paraplegia 8 | 313
Becker muscular dystrophy 7 | 187
COPD 7 | 113
Endometriosis 7 | 535
Neuropathy 7 | 210
interstitial lung disease 7 | 291
IGA Glomerulonephritis 6 | 454
Intellectual disability 6 | 573
Osteoporosis 6 | 257
Renal Cell Carcinoma 6 | 199
active Crohn's disease 6 | 918
gastric cancer 6 | 430
tuberculosis and treatment for 3 months 6 | 327
Amyotrophic Lateral Sclerosis 5 | 431
Bipolar Disorder 5 | 266
Chronic Lymphocytic Leukemia 5 | 242
Hypertension 5 | 287
Kidney cancer 5 | 118
Myopathy 5 | 128
Prostatic Neoplasms 5 | 471
Schizophrenia 5 | 501
tuberculosis and treatment for 6 months 5 | 686
pterygium 4 | 74
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 161 | 18,473
Female tissues 161 | 18,647
Nervous System 160 | 18,561
Urinary Tract 160 | 18,444
Cardiovascular System 159 | 17,958
Endocrine System 159 | 18,512
Liver and Pancreas 159 | 18,136
Blood and immune system 158 | 17,995
Male tissues 158 | 17,969
Skin and soft tissues 158 | 18,115
Respiratory system 155 | 17,484

Target Family

Non-IDG 152 | 11,971
Enzyme 9 | 4,146

PANTHER Protein Class (2)

non-motor actin binding protei... 161 | 161
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Wiskott-Aldrich syndrome protein family member 3 WASF3 Tbio Non-IDG -2.43045 280.1 123
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
Beta-1-syntrophin SNTB1 Tbio Non-IDG -1.02258 8.71 102
PDZ and LIM domain protein 4 PDLIM4 Tbio Non-IDG -1.99850 96.3 135
WD repeat-containing protein 1 WDR1 Tbio Non-IDG -1.58081 43.3 85
Profilin-4 PFN4 Tdark Non-IDG -0.52386 3.41 21
Abnormal spindle-like microcephaly-associated protein ASPM Tbio Non-IDG -1.42381 27.6 27
Espin-like protein ESPNL Tdark Non-IDG 0.38 0.47 56
Calponin-1 CNN1 Tbio Non-IDG -2.15513 149.7 268