Development Level

Tbio 45 | 11,651
Tdark 13 | 6,593
Tchem 4 | 1,388

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal embryo size 4 | 220
cyanosis 2 | 7
hyperactivity 2 | 148
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal limb morphology 1 | 13
abnormal outer ear morphology 1 | 3
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 58 | 11,493
ovarian cancer 31 | 8,520
medulloblastoma, large-cell 30 | 6,241
osteosarcoma 30 | 7,950
lung cancer 28 | 4,740
Breast cancer 26 | 3,578
atypical teratoid / rhabdoid tumor 26 | 5,112
ependymoma 26 | 4,679
glioblastoma 25 | 5,792
Kidney cancer 24 | 2,613
psoriasis 24 | 6,694
adult high grade glioma 22 | 3,801
group 3 medulloblastoma 22 | 4,104
malignant mesothelioma 20 | 3,232
Liver cancer 18 | 604
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 16 | 2,951
nasopharyngeal carcinoma 16 | 1,058
non-small cell lung cancer 16 | 2,890
primitive neuroectodermal tumor 16 | 3,035
Astrocytoma, Pilocytic 15 | 3,081
Endometrial cancer 13 | 311
adrenocortical carcinoma 13 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung adenocarcinoma 13 | 2,716
pancreatic cancer 12 | 2,398
Atopic dermatitis 11 | 952
colon cancer 11 | 1,478
ductal carcinoma in situ 11 | 1,745
lung carcinoma 11 | 2,843
Endometriosis 10 | 540
chronic rhinosinusitis 10 | 512
oligodendroglioma 10 | 2,850
breast carcinoma 9 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Melanoma 8 | 711
Primary ciliary dyskinesia 8 | 76
pituitary cancer 8 | 1,972
Small head 7 | 374
Autosomal recessive predisposition 6 | 1,442
Epilepsy 6 | 792
Large intestine cancer 6 | 126
Microcephaly 6 | 166
Pick disease 6 | 1,894
Skin cancer 6 | 469
astrocytic glioma 6 | 2,597
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
subependymal giant cell astrocytoma 6 | 2,287
Cancer 5 | 2,499
DOID:2627 5 | 94
Intellectual disability 5 | 1,016
Neurodegenerative disease 5 | 414
Neuropathy 5 | 261
Paraplegia 5 | 74
Seizures 5 | 596
ulcerative colitis 5 | 1,819
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Male infertility 4 | 206
Mental and motor retardation 4 | 608
astrocytoma 4 | 1,146
cystic fibrosis and chronic rhinosinusitis 4 | 214
diabetes mellitus 4 | 1,728
fibroadenoma 4 | 559
Amyotrophic lateral sclerosis 3 | 451
Anteverted nostril 3 | 191
Babinski Reflex 3 | 100
Bipolar Disorder 3 | 666
Congenital pes cavus 3 | 88
Decreased tendon reflex 3 | 122
Distal sensory impairment 3 | 52
Downward slant of palpebral fissure 3 | 158
Dull intelligence 3 | 645
Fetal Growth Retardation 3 | 189
Hyperreflexia 3 | 209
Immune system cancer 3 | 140
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Kartagener Syndrome 3 | 38
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Polydactyly 3 | 107
Poor school performance 3 | 645
Progressive disorder 3 | 142
Recurrent respiratory infections 3 | 141
Right atrial isomerism 3 | 29
Schizophrenia 3 | 1,160
Situs Inversus 3 | 65
Sloping forehead 3 | 46
Slow progression 3 | 89
cutaneous lupus erythematosus 3 | 1,057
facioscapulohumeral dystrophy 3 | 288
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074

Tissue

Endocrine System 61 | 18,159
Respiratory system 59 | 16,393
Skin and soft tissues 59 | 17,230
Digestive Tract 58 | 17,369
Female tissues 58 | 17,400
Male tissues 58 | 17,142
Nervous System 56 | 16,725
Urinary Tract 56 | 16,678
Blood and immune system 55 | 16,909
Liver and Pancreas 55 | 16,750
Cardiovascular System 49 | 15,192

Target Family

Non-IDG 62 | 12,091

PANTHER Protein Class (2)

microtubule binding motor prot... 62 | 62
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein heavy chain 6, axonemal DNAH6 Tbio Non-IDG -0.53057 4.17 18
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
Kinesin-like protein KIF6 KIF6 Tbio Non-IDG -1.53414 38.4 157
Dynein heavy chain 14, axonemal DNAH14 Tdark Non-IDG -0.25794 1.89 55
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.37859 20.9 98
Dynactin subunit 2 DCTN2 Tbio Non-IDG -1.88460 67.4 257
Dynactin subunit 6 DCTN6 Tdark Non-IDG 0.18 0.53 108
Kinesin-like protein KIF14 KIF14 Tbio Non-IDG -1.46037 34.0 93
Kinesin-associated protein 3 KIFAP3 Tbio Non-IDG -1.36007 24.1 87