Development Level

Tbio 35 | 10,625
Tchem 25 | 1,890
Tdark 13 | 7,003
Tclin 2 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal cranium morphology 2 | 32
decreased body weight 2 | 174
decreased prepulse inhibition 2 | 52
abnormal behavior 1 | 226
abnormal body size 1 | 1
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal femur morphology 1 | 14
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 3
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal maxilla morphology 1 | 16
abnormal radius morphology 1 | 8
abnormal tail morphology 1 | 17
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
decreased CD5-positive Ly6C-po... 1 | 4
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating phosphat... 1 | 15
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased food intake 1 | 6
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased respiratory quotient 1 | 12
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
enlarged liver 1 | 3
female infertility 1 | 34
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased KLRG1-positive NK ce... 1 | 9
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating potassiu... 1 | 31
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased transitional stage T... 1 | 1
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
thick tail 1 | 1

Disease

osteosarcoma 44 | 7,933
ovarian cancer 41 | 8,484
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
psoriasis 24 | 6,685
medulloblastoma, large-cell 23 | 6,234
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
invasive ductal carcinoma 20 | 2,950
lung cancer 20 | 4,466
glioblastoma 19 | 5,572
atypical teratoid / rhabdoid tumor 18 | 4,369
lung carcinoma 14 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
non-small cell lung cancer 13 | 2,798
Breast cancer 12 | 3,094
interstitial cystitis 12 | 2,299
oligodendroglioma 12 | 2,849
ductal carcinoma in situ 11 | 1,745
malignant mesothelioma 11 | 3,162
breast carcinoma 10 | 1,614
cystic fibrosis 10 | 1,665
lung adenocarcinoma 10 | 2,713
primitive neuroectodermal tumor 10 | 3,031
Carcinoma 9 | 2,147
Pick disease 9 | 1,893
adult high grade glioma 9 | 2,148
diabetes mellitus 9 | 1,663
group 3 medulloblastoma 9 | 2,254
ulcerative colitis 9 | 2,087
astrocytic glioma 8 | 2,241
pancreatic cancer 8 | 2,300
pediatric high grade glioma 8 | 2,712
posterior fossa group A ependymoma 8 | 1,511
Multiple myeloma 7 | 1,327
ependymoma 7 | 2,514
pilocytic astrocytoma 7 | 3,086
pituitary cancer 7 | 1,972
Waldenstrons macroglobulinemia 6 | 765
group 4 medulloblastoma 6 | 1,875
tuberculosis 6 | 1,557
Alzheimer's disease 5 | 644
Atopic dermatitis 5 | 944
Rheumatoid Arthritis 5 | 1,160
active Crohn's disease 5 | 918
acute myeloid leukemia 5 | 780
acute quadriplegic myopathy 5 | 1,157
adrenocortical carcinoma 5 | 1,427
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
juvenile dermatomyositis 5 | 1,189
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
Hypertension 4 | 287
Neurodegenerative disease 4 | 383
atypical teratoid/rhabdoid tumor 4 | 1,095
gastric carcinoma 4 | 832
posterior fossa group B ependymoma 4 | 1,530
sonic hedgehog group medulloblastoma 4 | 1,482
spina bifida 4 | 1,064
Anemia 3 | 252
Angioedema 3 | 36
Asthma 3 | 349
Cancer 3 | 2,346
Craniofacial Abnormalities 3 | 147
Intellectual disability 3 | 573
Obesity 3 | 616
Paraplegia 3 | 71
Silver-Russell syndrome 3 | 37
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
esophageal adenocarcinoma 3 | 737
interstitial lung disease 3 | 291
medulloblastoma 3 | 1,524
nephrosclerosis 3 | 329
Acquired metabolic disease 2 | 267
Amyotrophic Lateral Sclerosis 2 | 431
Atherosclerosis 2 | 275
Chronic progressive external ophthalmoplegia 2 | 18
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Duchenne muscular dystrophy 2 | 602
Endometriosis 2 | 535
Essential Hypertension 2 | 82
Hearing Loss, Partial 2 | 25
Hepatitis B 2 | 103
Hypertensive disease 2 | 193
Kidney disease 2 | 396
Leishmaniasis 2 | 49
Osteoporosis 2 | 257
Ptosis 2 | 42
Type 2 diabetes mellitus 2 | 189
active ulcerative colitis 2 | 477
aldosterone-producing adenoma 2 | 664
chronic rhinosinusitis 2 | 512
glioblastoma multiforme 2 | 347
hearing impairment 2 | 40
mucosa-associated lymphoid tissue lymphoma 2 | 480
non-small cell lung carcinoma 2 | 413
progressive supranuclear palsy 2 | 674
tuberculosis and treatment for 3 months 2 | 327
urothelial carcinoma 2 | 318

Tissue

Endocrine System 74 | 18,512
Female tissues 74 | 18,647
Male tissues 74 | 17,969
Nervous System 74 | 18,561
Blood and immune system 73 | 17,995
Cardiovascular System 73 | 17,958
Digestive Tract 73 | 18,473
Liver and Pancreas 73 | 18,136
Respiratory system 73 | 17,484
Skin and soft tissues 73 | 18,115
Urinary Tract 73 | 18,444

Target Family

Enzyme 72 | 4,146
Non-IDG 2 | 11,971
Kinase 1 | 634

PANTHER Protein Class (2)

metalloprotease 75 | 75
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Xaa-Pro aminopeptidase 2 XPNPEP2 Tchem Enzyme -1.55651 32.2 97
Nardilysin NRDC Tbio Enzyme -1.64244 49.9 83
Endoplasmic reticulum aminopeptidase 1 ERAP1 Tchem Enzyme -2.22270 198.7 195
Glutamyl aminopeptidase ENPEP Tchem Enzyme -2.81004 644.6 267
Insulin-degrading enzyme IDE Tchem Enzyme -2.54789 384.2 283
Kell blood group glycoprotein KEL Tbio Enzyme -2.57345 371.0 161
Methionine aminopeptidase 2 METAP2 Tchem Enzyme -1.90718 91.8 157
Carboxypeptidase O CPO Tdark Enzyme -0.33099 2.01 78
Probable carboxypeptidase X1 CPXM1 Tdark Enzyme -0.36173 2.70 60
Carboxypeptidase E CPE Tbio Enzyme -2.97987 983.1 216