Development Level

Tbio 89 | 10,625
Tdark 36 | 7,003
Tchem 4 | 1,890

IMPC Phenotype

preweaning lethality, complete... 9 | 633
abnormal behavior 3 | 226
embryonic lethality prior to o... 3 | 148
hyperactivity 3 | 108
abnormal bone structure 2 | 131
decreased circulating glucose ... 2 | 121
increased fasted circulating g... 2 | 68
increased or absent threshold ... 2 | 128
preweaning lethality, incomple... 2 | 260
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal lens morphology 1 | 73
abnormal neural tube morpholog... 1 | 8
abnormal retinal pigmentation 1 | 61
aorta dilation 1 | 3
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
embryonic lethality prior to t... 1 | 187
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased prepulse inhibition 1 | 21
increased total body fat amoun... 1 | 57
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
sparse hair 1 | 6
straub tail 1 | 26
thrombocytosis 1 | 23

Disease

ovarian cancer 71 | 8,491
osteosarcoma 62 | 7,933
medulloblastoma, large-cell 51 | 6,234
psoriasis 49 | 6,685
glioblastoma 38 | 5,572
lung cancer 38 | 4,473
group 3 medulloblastoma 33 | 2,254
malignant mesothelioma 28 | 3,163
atypical teratoid / rhabdoid tumor 24 | 4,369
oligodendroglioma 24 | 2,849
Breast cancer 23 | 3,098
acute quadriplegic myopathy 23 | 1,157
ependymoma 23 | 2,514
primitive neuroectodermal tumor 23 | 3,031
Multiple myeloma 21 | 1,327
Pick disease 20 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
astrocytoma 18 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
Carcinoma 17 | 2,147
lung adenocarcinoma 16 | 2,714
astrocytic glioma 15 | 2,241
diabetes mellitus 15 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
pediatric high grade glioma 15 | 2,712
sonic hedgehog group medulloblastoma 15 | 1,482
non-small cell lung cancer 14 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
adult high grade glioma 12 | 2,148
acute myeloid leukemia 11 | 785
atypical teratoid/rhabdoid tumor 11 | 1,095
subependymal giant cell astrocytoma 11 | 2,287
group 4 medulloblastoma 10 | 1,875
invasive ductal carcinoma 10 | 2,950
Gaucher disease type 1 9 | 171
dermatomyositis 9 | 966
hepatocellular carcinoma 9 | 550
progressive supranuclear palsy 9 | 674
Intellectual disability 8 | 573
Waldenstrons macroglobulinemia 8 | 764
aldosterone-producing adenoma 8 | 664
lung carcinoma 8 | 2,844
Amyotrophic Lateral Sclerosis 7 | 432
Cancer 7 | 2,346
breast carcinoma 7 | 1,614
interstitial lung disease 7 | 292
juvenile dermatomyositis 7 | 1,189
medulloblastoma 7 | 1,524
pancreatic cancer 7 | 2,300
pilocytic astrocytoma 7 | 3,086
pituitary cancer 7 | 1,972
spina bifida 7 | 1,064
Retinitis pigmentosa 6 | 156
Schizophrenia 6 | 503
colon cancer 6 | 1,475
nasopharyngeal carcinoma 6 | 1,056
Disease Progression 5 | 125
Rheumatoid Arthritis 5 | 1,170
Stomach Neoplasms 5 | 282
Cardiovascular system disease 4 | 194
Epilepsy 4 | 346
gastric carcinoma 4 | 832
interstitial cystitis 4 | 2,299
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511
posterior fossa group B ependymoma 4 | 1,530
tuberculosis and treatment for 6 months 4 | 686
Atopic dermatitis 3 | 944
Down syndrome 3 | 548
Frontotemporal dementia 3 | 47
HIV Infections 3 | 99
Lupus erythematosus 3 | 80
Melanoma 3 | 261
Microcephaly 3 | 149
Multiple Sclerosis 3 | 498
Neurodegenerative disease 3 | 383
adrenocortical carcinoma 3 | 1,427
glioblastoma multiforme 3 | 347
mucosa-associated lymphoid tissue lymphoma 3 | 480
primary Sjogren syndrome 3 | 788
sarcoidosis 3 | 368
tuberculosis and treatment for 3 months 3 | 327
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Autistic Disorder 2 | 320
Chronic obstructive pulmonary disease 2 | 147
Cockayne syndrome 2 | 54
Crohn's disease 2 | 304
Kidney disease 2 | 397
Lissencephaly 2 | 61
Male infertility 2 | 170
Peripheral Neuropathy 2 | 303
Polycystic Ovary Syndrome 2 | 334
Pontocerebellar hypoplasia 2 | 29
Type 2 diabetes mellitus 2 | 192
chronic lymphocytic leukemia 2 | 244
hereditary spastic paraplegia 2 | 313
non-small cell lung carcinoma 2 | 413
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis 2 | 1,563

Tissue

Blood and immune system 129 | 17,994
Cardiovascular System 129 | 17,957
Digestive Tract 129 | 18,472
Endocrine System 129 | 18,511
Female tissues 129 | 18,646
Liver and Pancreas 129 | 18,135
Male tissues 129 | 17,968
Nervous System 129 | 18,560
Respiratory system 129 | 17,483
Urinary Tract 129 | 18,443
Skin and soft tissues 126 | 18,114

Target Family

Non-IDG 116 | 11,969
Enzyme 12 | 4,146
Kinase 1 | 634

PANTHER Protein Class (2)

mRNA processing factor 129 | 129
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein FUS FUS Tbio Non-IDG -3.13445 1454.2 252
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.14092 1352.4 99
U1 small nuclear ribonucleoprotein A SNRPA Tbio Non-IDG -3.08272 1144.5 225
RNA-binding protein EWS EWSR1 Tbio Non-IDG -3.01326 1055.2 389
U4/U6 small nuclear ribonucleoprotein Prp3 PRPF3 Tbio Non-IDG -1.71435 998.6 107
Small nuclear ribonucleoprotein E SNRPE Tbio Non-IDG -2.74303 540.8 230
Serine/threonine-protein kinase Kist UHMK1 Tbio Kinase -2.71415 503.6 210
Non-POU domain-containing octamer-binding protein NONO Tbio Non-IDG -2.71692 487.5 288
U1 small nuclear ribonucleoprotein 70 kDa SNRNP70 Tbio Non-IDG -2.66978 426.5 125
U5 small nuclear ribonucleoprotein 40 kDa protein SNRNP40 Tbio Non-IDG -2.62626 397.7 83