Development Level

Tbio 93 | 11,178
Tdark 22 | 6,569
Tchem 3 | 1,885

IMPC Phenotype

preweaning lethality, complete... 13 | 979
abnormal behavior 5 | 298
embryonic lethality prior to o... 4 | 239
hyperactivity 3 | 148
increased fasted circulating g... 3 | 76
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased circulating creatini... 2 | 38
increased or absent threshold ... 2 | 101
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal sleep behavior 1 | 70
aorta dilation 1 | 3
decreased IgE level 1 | 6
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to t... 1 | 278
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thin ventricular wall 1 | 24

Disease

Carcinoma 78 | 11,192
ovarian cancer 68 | 8,297
osteosarcoma 60 | 7,766
psoriasis 44 | 6,514
medulloblastoma, large-cell 43 | 6,086
group 3 medulloblastoma 39 | 4,002
glioblastoma 36 | 5,635
lung cancer 33 | 4,607
atypical teratoid / rhabdoid tumor 32 | 4,971
ependymoma 30 | 4,559
malignant mesothelioma 28 | 3,135
primitive neuroectodermal tumor 25 | 2,957
Multiple myeloma 24 | 1,296
oligodendroglioma 24 | 2,768
Pick disease 23 | 1,856
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,902
Breast cancer 21 | 3,469
Kidney cancer 21 | 2,548
acute quadriplegic myopathy 21 | 1,133
astrocytic glioma 20 | 2,530
adult high grade glioma 18 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,204
diabetes mellitus 16 | 1,683
lung adenocarcinoma 16 | 2,627
non-small cell lung cancer 16 | 2,799
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,872
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,911
Waldenstrons macroglobulinemia 13 | 742
dermatomyositis 13 | 941
astrocytoma 12 | 1,113
invasive ductal carcinoma 12 | 2,867
progressive supranuclear palsy 12 | 656
subependymal giant cell astrocytoma 12 | 2,230
Cancer 10 | 2,388
Gaucher disease type 1 9 | 177
Intellectual disability 9 | 998
acute myeloid leukemia 8 | 760
breast carcinoma 8 | 1,589
group 4 medulloblastoma 8 | 1,806
hepatocellular carcinoma 8 | 536
juvenile dermatomyositis 8 | 1,147
pituitary cancer 8 | 1,915
Astrocytoma, Pilocytic 7 | 3,006
Dull intelligence 7 | 634
Low intelligence 7 | 634
Mental Retardation 7 | 634
Mental deficiency 7 | 634
Obesity 7 | 655
Poor school performance 7 | 634
Rheumatoid arthritis 7 | 1,156
aldosterone-producing adenoma 7 | 646
pancreatic cancer 7 | 2,322
spina bifida 7 | 1,053
Broad flat nasal bridge 6 | 232
Conductive hearing loss 6 | 122
Glaucoma 6 | 232
Male infertility 6 | 199
Nasal bridge wide 6 | 232
Nystagmus 6 | 309
Schizophrenia 6 | 1,136
colon cancer 6 | 1,428
interstitial lung disease 6 | 287
nasopharyngeal carcinoma 6 | 1,024
sonic hedgehog group medulloblastoma 6 | 459
Abnormality of retinal pigmentation 5 | 109
Abnormality of the retinal vasculature 5 | 58
Amyotrophic lateral sclerosis 5 | 437
Anteverted nostril 5 | 186
Atypical scarring of skin 5 | 61
Blind Vision 5 | 110
Blindness, Legal 5 | 109
Cataract 5 | 290
Congenital anomaly of testis 5 | 51
Congenital hypoplasia of penis 5 | 168
Electroretinogram abnormal 5 | 94
HIV Infections 5 | 94
Hyperinsulinism 5 | 128
Hypogonadism 5 | 169
Keratoconus 5 | 111
Lens Opacities 5 | 227
Night blindness, progressive 5 | 50
Ophthalmoplegia 5 | 105
Optic Atrophy 5 | 239
Photodysphoria 5 | 117
Photophobia 5 | 117
Retinal pigment epithelial abnormality 5 | 109
Retinitis Pigmentosa 5 | 223
Sensorineural Hearing Loss (disorder) 5 | 281
lung carcinoma 5 | 2,755
non primary Sjogren syndrome sicca 5 | 861
pediatric high grade glioma 5 | 1,035
Disease Progression 4 | 133
Polycystic ovary syndrome 4 | 348
Stomach Neoplasms 4 | 287
adrenocortical carcinoma 4 | 1,385
atypical teratoid/rhabdoid tumor 4 | 349
ductal carcinoma in situ 4 | 1,686
interstitial cystitis 4 | 2,237
tuberculosis 4 | 1,963
tuberculosis and treatment for 3 months 4 | 175

Tissue

Endocrine System 117 | 18,159
Female tissues 112 | 17,400
Male tissues 112 | 17,142
Respiratory system 112 | 16,393
Blood and immune system 111 | 16,909
Digestive Tract 111 | 17,369
Liver and Pancreas 111 | 16,750
Nervous System 111 | 16,725
Skin and soft tissues 111 | 17,230
Urinary Tract 111 | 16,678
Cardiovascular System 109 | 15,192

Target Family

Non-IDG 108 | 12,091
Enzyme 10 | 4,145

PANTHER Protein Class (2)

mRNA processing factor 118 | 118
protein kinase 252 | 252
ribosomal protein 149 | 149
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease 98 | 98
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 85 | 85
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
cysteine protease 58 | 58
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
metalloprotease 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
aspartic protease 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
interleukin superfamily 4 | 4
C2H2 zinc finger transcription... 3 | 3
CREB-related transcription fac... 3 | 3
DNA photolyase 2 | 2
DNA topoisomerase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA damage-binding protein 1 DDB1 Tchem Non-IDG -2.34719 202.5 353
Target of EGR1 protein 1 TOE1 Tbio Non-IDG -1.37536 23.1 140
Serine/arginine-rich splicing factor 7 SRSF7 Tbio Non-IDG -1.19691 12.9 177
RNA-binding motif protein, Y chromosome, family 1 member F/J RBMY1J Tdark Non-IDG 0.31 0.53 49
Splicing factor 3B subunit 3 SF3B3 Tchem Non-IDG -1.28872 19.5 222
Pre-mRNA-processing factor 17 CDC40 Tbio Non-IDG -1.37680 24.3 102
RNA-binding motif protein, X-linked-like-3 RBMXL3 Tdark Non-IDG 0.78 0.08 0
Ubiquitin carboxyl-terminal hydrolase 43 USP43 Tdark Enzyme 0.48 0.33 121
Ubiquitin carboxyl-terminal hydrolase 31 USP31 Tbio Enzyme 0.48 0.00000 42
Tuftelin-interacting protein 11 TFIP11 Tbio Non-IDG -1.75990 66.6 84