Development Level

Tclin 32 | 612
Tchem 18 | 1,388
Tbio 16 | 11,651
Tdark 3 | 6,593

Collection

Ion Channel: IDG Consortium (T... 14 | 99
RFA-RM-18-021 13 | 328

IMPC Phenotype

enlarged heart 4 | 210
preweaning lethality, complete... 4 | 979
abnormal heart morphology 2 | 162
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal clavicle morphology 1 | 6
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal pancreas morphology 1 | 13
abnormal testis morphology 1 | 43
brachydactyly 1 | 19
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
impaired glucose tolerance 1 | 75
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 56 | 11,493
psoriasis 33 | 6,694
Epilepsy 27 | 792
medulloblastoma, large-cell 26 | 6,241
General anesthesia 23 | 53
atypical teratoid / rhabdoid tumor 23 | 5,112
glioblastoma 22 | 5,792
Astrocytoma, Pilocytic 21 | 3,081
Schizophrenia 21 | 1,160
Alcoholic Intoxication, Chronic 19 | 289
Kidney cancer 19 | 2,613
adult high grade glioma 19 | 3,801
ependymoma 19 | 4,679
Bipolar Disorder 18 | 666
Nicotine dependence 18 | 54
group 3 medulloblastoma 18 | 4,104
osteosarcoma 18 | 7,950
Anxiety 17 | 136
Autistic Disorder 17 | 364
Insomnia 16 | 20
Tonic-clonic epilepsy 16 | 47
astrocytic glioma 16 | 2,597
ovarian cancer 16 | 8,520
Alcohol dependence 15 | 107
lung carcinoma 15 | 2,843
oligodendroglioma 15 | 2,850
primitive neuroectodermal tumor 15 | 3,035
Breast cancer 14 | 3,578
Sedation as Adjunct to Anesthesia 13 | 15
lung cancer 13 | 4,740
Depressive disorder 12 | 409
Irritable bowel syndrome 12 | 60
Autosomal recessive predisposition 11 | 1,442
Seizures 11 | 596
subependymal giant cell astrocytoma 11 | 2,287
Mental Depression 10 | 333
Pick disease 10 | 1,894
Spasticity 10 | 26
Muscle hypotonia 9 | 571
Panic disorder 9 | 61
Schizoaffective Disorder 9 | 55
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pituitary cancer 9 | 1,972
Alcohol withdrawal delirium 8 | 11
Alcohol withdrawal syndrome 8 | 20
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Chemotherapy-induced nausea and vomiting 8 | 18
Generalized anxiety disorder 8 | 29
Induce Anterograde Amnesia 8 | 9
Local anesthesia 8 | 40
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Status Epilepticus 8 | 98
Tetanus 8 | 68
pancreatic cancer 8 | 2,398
Anxiety associated with Menopause 7 | 7
Conscious sedation 7 | 10
Feeling agitated 7 | 7
Frontal lobe epilepsy 7 | 10
Intellectual disability 7 | 1,016
Liver cancer 7 | 604
Mixed anxiety and depressive disorder 7 | 12
Mood Disorders 7 | 184
Muscle relaxation, function 7 | 8
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic Ulcer 7 | 27
Pre-Op Apprehension 7 | 10
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
Alcoholism 6 | 45
Blepharoptosis 6 | 231
Byzanthine arch palate 6 | 194
Cocaine Dependence 6 | 51
Gastroesophageal reflux disease 6 | 110
Initial insomnia 6 | 8
Multiple pterygium syndrome 6 | 18
Pain with Tension and Anxiety 6 | 6
Smoking cessation assistance 6 | 8
ulcerative colitis 6 | 1,819
Bell Palsy 5 | 58
Diabetic gastroparesis 5 | 7
Facial Paresis 5 | 59
Facial muscle weakness of muscles innervated by CN VII 5 | 58
Gastrointestinal Radiography Adjunct 5 | 11
Infantile onset 5 | 238
Intubation of gastrointestinal tract 5 | 7
Neuropathy 5 | 261
Pellagra 5 | 26
Prevention of Post-Operative Nausea and Vomiting 5 | 14
cystic fibrosis 5 | 1,696
invasive ductal carcinoma 5 | 2,951
substance-related disorder 5 | 162

Tissue

Endocrine System 64 | 18,159
Nervous System 59 | 16,725
Digestive Tract 57 | 17,369
Female tissues 56 | 17,400
Skin and soft tissues 55 | 17,230
Blood and immune system 53 | 16,909
Male tissues 52 | 17,142
Urinary Tract 47 | 16,678
Liver and Pancreas 46 | 16,750
Respiratory system 42 | 16,393
Cardiovascular System 38 | 15,192

Target Family

Ion Channel 59 | 344
GPCR 5 | 408
Non-IDG 5 | 12,091

PANTHER Protein Class (2)

ligand-gated ion channel 69 | 69
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Tclin Ion Channel -1.57182 33.7 130
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.25430 179.4 244
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.38661 2426.7 262
P2X purinoceptor 6 P2RX6 Tbio Ion Channel -1.46307 26.2 147
P2X purinoceptor 1 P2RX1 Tchem Ion Channel -2.41145 259.4 137
P2X purinoceptor 5 P2RX5 Tbio Ion Channel -1.56458 35.6 136
Gamma-aminobutyric acid receptor subunit alpha-6 GABRA6 Tclin Ion Channel -1.30795 19.3 145
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 Tclin Ion Channel -1.99577 92.1 193
Glycine receptor subunit alpha-2 GLRA2 Tchem Ion Channel -1.03360 12.0 33
Glycine receptor subunit alpha-1 GLRA1 Tclin Ion Channel -2.08638 119.0 306