Development Level

Tclin 60 | 602
Tchem 28 | 1,890
Tbio 13 | 10,625
Tdark 3 | 7,003

Collection

Eligible Ion Channel Proteins 31 | 117

IMPC Term

enlarged heart 3 | 111
decreased body weight 2 | 174
decreased eosinophil cell numb... 2 | 41
embryonic lethality prior to t... 2 | 187
increased startle reflex 2 | 38
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
corneal opacity 1 | 25
decreased B cell number 1 | 30
decreased NK T cell number 1 | 28
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating glycerol... 1 | 19
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
increased CD4-positive, CD25-p... 1 | 18
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased fasted circulating g... 1 | 68
preweaning lethality, incomple... 1 | 260
small epididymis 1 | 3
small testis 1 | 37
thrombocytopenia 1 | 46

Disease

psoriasis 50 | 6,685
Carcinoma 46 | 2,147
medulloblastoma, large-cell 44 | 6,234
Epilepsy 38 | 346
glioblastoma 37 | 5,572
General anesthesia 34 | 53
atypical teratoid / rhabdoid tumor 33 | 4,369
pilocytic astrocytoma 31 | 3,086
lung carcinoma 29 | 2,844
osteosarcoma 29 | 7,933
oligodendroglioma 27 | 2,849
primitive neuroectodermal tumor 27 | 3,031
Schizophrenia 26 | 501
Tonic-clonic epilepsy 25 | 47
ependymoma 22 | 2,514
ovarian cancer 22 | 8,484
pediatric high grade glioma 22 | 2,712
astrocytic glioma 21 | 2,241
Autistic Disorder 19 | 320
Local anesthesia 19 | 40
medulloblastoma 18 | 1,524
subependymal giant cell astrocytoma 18 | 2,287
Alcohol dependence 17 | 107
Nicotine dependence 17 | 53
Anxiety 16 | 24
Insomnia 16 | 20
Pick disease 16 | 1,893
Lennox-Gastaut syndrome 15 | 34
adult high grade glioma 15 | 2,148
lung cancer 15 | 4,466
pituitary cancer 15 | 1,972
Simple partial seizure 14 | 26
Bipolar Disorder 13 | 266
Breast cancer 13 | 3,094
Sedation as Adjunct to Anesthesia 13 | 15
Epilepsy characterized by intractable complex partial seizures 12 | 28
Irritable bowel syndrome 12 | 59
Migraine Prevention 12 | 22
Parkinson's disease 12 | 364
group 4 medulloblastoma 12 | 1,875
Intellectual disability 11 | 573
posterior fossa group A ependymoma 11 | 1,511
Alcoholism 10 | 14
Multiple Sclerosis 10 | 498
Panic disorder 10 | 55
Spasticity 10 | 26
group 3 medulloblastoma 10 | 2,254
interstitial cystitis 10 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
Status Epilepticus 9 | 85
Tetanus 9 | 66
astrocytoma 9 | 1,493
atypical teratoid/rhabdoid tumor 9 | 1,095
lung adenocarcinoma 9 | 2,713
Alcohol withdrawal delirium 8 | 9
Alcohol withdrawal syndrome 8 | 9
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Chemotherapy-induced nausea and vomiting 8 | 18
Eaton-Lambert syndrome 8 | 40
Generalized anxiety disorder 8 | 29
Induce Anterograde Amnesia 8 | 9
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
malignant mesothelioma 8 | 3,162
Alzheimer's disease 7 | 644
Anxiety associated with Menopause 7 | 7
Arteriosclerotic Parkinsonism 7 | 8
Conscious sedation 7 | 10
Extrapyramidal disease 7 | 8
Feeling agitated 7 | 7
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Major Depressive Disorder 7 | 106
Mixed anxiety and depressive disorder 7 | 10
Muscle relaxation, function 7 | 8
Parkinsonism 7 | 19
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic ulcer 7 | 22
Postencephalitic parkinsonism 7 | 12
Pre-Op Apprehension 7 | 10
Seizures 7 | 95
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
Substance Withdrawal Syndrome 7 | 52
Toxic encephalopathy 7 | 131
non primary Sjogren syndrome sicca 7 | 840
sonic hedgehog group medulloblastoma 7 | 1,482
ulcerative colitis 7 | 2,087
Frontal lobe epilepsy 6 | 8
Initial insomnia 6 | 8
Multiple pterygium syndrome 6 | 17
Pain with Tension and Anxiety 6 | 6
Smoking cessation assistance 6 | 8
pancreatic cancer 6 | 2,300
posterior fossa group B ependymoma 6 | 1,530

Tissue

Female tissues 104 | 18,647
Digestive Tract 103 | 18,473
Endocrine System 103 | 18,512
Nervous System 103 | 18,561
Urinary Tract 103 | 18,444
Liver and Pancreas 102 | 18,136
Skin and soft tissues 101 | 18,115
Cardiovascular System 98 | 17,958
Male tissues 97 | 17,969
Blood and immune system 96 | 17,995
Respiratory system 96 | 17,484

Target Family

Ion Channel 95 | 341
GPCR 5 | 406
Non-IDG 4 | 11,971

PANTHER Protein Class (2)

ligand-gated ion channel 104 | 104
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.19758 165.4 232
Taste receptor type 1 member 1 TAS1R1 Tbio GPCR -1.71516 50.8 165
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.23749 17.4 128
Glycine receptor subunit beta GLRB Tclin Ion Channel -1.15613 15.9 85
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.37968 2392.4 232
P2X purinoceptor 6 P2RX6 Tchem Ion Channel -1.46223 26.9 118
Acetylcholine receptor subunit beta CHRNB1 Tclin Ion Channel -1.24555 17.5 166