Development Level

Tbio 33 | 10,625
Tdark 11 | 7,003
Tchem 3 | 1,890

IMPC Phenotype

preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal epididymis morphology 1 | 31
abnormal eye size 1 | 11
abnormal heart morphology 1 | 51
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
decreased neutrophil cell numb... 1 | 37
enlarged epididymis 1 | 27
enlarged heart 1 | 111
enlarged spleen 1 | 26
impaired glucose tolerance 1 | 52
increased exploration in new e... 1 | 56
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 25
increased or absent threshold ... 1 | 128
limb grasping 1 | 35
small testis 1 | 37

Disease

ovarian cancer 28 | 8,491
osteosarcoma 26 | 7,933
atypical teratoid / rhabdoid tumor 19 | 4,369
medulloblastoma, large-cell 19 | 6,234
glioblastoma 18 | 5,572
lung cancer 17 | 4,473
psoriasis 14 | 6,685
malignant mesothelioma 13 | 3,163
pilocytic astrocytoma 12 | 3,086
ependymoma 11 | 2,514
invasive ductal carcinoma 11 | 2,950
subependymal giant cell astrocytoma 11 | 2,287
Breast cancer 10 | 3,098
Cancer 10 | 2,346
astrocytic glioma 10 | 2,241
pituitary cancer 10 | 1,972
adult high grade glioma 9 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
medulloblastoma 9 | 1,524
cystic fibrosis 8 | 1,670
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
non-small cell lung cancer 8 | 2,798
pediatric high grade glioma 8 | 2,712
primitive neuroectodermal tumor 8 | 3,031
ulcerative colitis 8 | 2,087
group 4 medulloblastoma 7 | 1,875
juvenile dermatomyositis 7 | 1,189
oligodendroglioma 7 | 2,849
adrenocortical carcinoma 6 | 1,427
breast carcinoma 6 | 1,614
lung adenocarcinoma 6 | 2,714
lung carcinoma 6 | 2,844
non primary Sjogren syndrome sicca 6 | 840
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Pick disease 5 | 1,893
acute quadriplegic myopathy 5 | 1,157
colon cancer 5 | 1,475
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 2,254
interstitial cystitis 5 | 2,299
tuberculosis and treatment for 3 months 5 | 327
Atopic dermatitis 4 | 944
Carcinoma 4 | 2,147
Prostatic Neoplasms 4 | 471
Rheumatoid Arthritis 4 | 1,170
active Crohn's disease 4 | 918
pancreatic cancer 4 | 2,300
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511
spina bifida 4 | 1,064
Dermatitis, Allergic Contact 3 | 66
Duchenne muscular dystrophy 3 | 602
Lung Neoplasms 3 | 171
Multiple myeloma 3 | 1,327
Stomach Neoplasms 3 | 282
Waldenstrons macroglobulinemia 3 | 764
aldosterone-producing adenoma 3 | 664
diabetes mellitus 3 | 1,663
gastric carcinoma 3 | 832
head and neck cancer 3 | 270
hereditary spastic paraplegia 3 | 313
posterior fossa group B ependymoma 3 | 1,530
tuberculosis 3 | 1,563
Acquired metabolic disease 2 | 267
Adenoma 2 | 165
Bipolar Disorder 2 | 266
Carney complex 2 | 23
Endometrial Neoplasms 2 | 50
IGA Glomerulonephritis 2 | 454
Intestinal Neoplasms 2 | 11
Liver carcinoma 2 | 217
Liver diseases 2 | 66
Mammary Neoplasms 2 | 410
Multiple Endocrine Neoplasia Type 1 2 | 30
Multiple Sclerosis 2 | 498
Myocardial Ischemia 2 | 169
Obesity 2 | 616
Reperfusion Injury 2 | 84
Stuttering 2 | 18
Vascular disease 2 | 281
active ulcerative colitis 2 | 477
astrocytoma 2 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 966
fibroadenoma 2 | 557
gastric cancer 2 | 436
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
hepatocellular carcinoma 2 | 550
non diabetic and post-ischemic heart failure 2 | 200
periodontitis 2 | 269
primary pancreatic ductal adenocarcinoma 2 | 1,271
sarcoidosis 2 | 368
tuberculosis and treatment for 6 months 2 | 686
type II diabetes mellitus and post-ischemic heart failure 2 | 89
Gaucher disease type 1 1 | 171
Liver neoplasms 1 | 108
limb girdle muscular dystrophy 2B 1 | 74
systemic lupus erythematosus 1 | 172

Tissue

Digestive Tract 47 | 18,472
Nervous System 47 | 18,560
Blood and immune system 46 | 17,994
Cardiovascular System 46 | 17,957
Endocrine System 46 | 18,511
Female tissues 46 | 18,646
Liver and Pancreas 46 | 18,135
Male tissues 46 | 17,968
Respiratory system 46 | 17,483
Skin and soft tissues 46 | 18,114
Urinary Tract 46 | 18,443

Target Family

Enzyme 25 | 4,146
Non-IDG 21 | 11,969
Kinase 1 | 634

PANTHER Protein Class (2)

kinase inhibitor 47 | 47
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein phosphatase 1H PPM1H Tbio Enzyme -0.96031 10.6 89
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TAB1 Tbio Kinase -1.90358 73.6 452
cAMP-dependent protein kinase inhibitor beta PKIB Tbio Enzyme -0.78436 6.50 44
Regulation of nuclear pre-mRNA domain-containing protein 1B RPRD1B Tbio Non-IDG -1.21625 19.4 102
Protein phosphatase 1B PPM1B Tchem Enzyme -1.53234 35.1 159
Glutamine-rich protein 1 QRICH1 Tdark Non-IDG 0.95 0.16 17
cAMP-dependent protein kinase inhibitor alpha PKIA Tbio Enzyme -1.27069 18.5 26
Regulation of nuclear pre-mRNA domain-containing protein 2 RPRD2 Tdark Non-IDG 0.28 0.26 44
Protein phosphatase 1J PPM1J Tdark Enzyme 0.01 1.35 49
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.78671 600.5 488