Development Level

Tbio 20 | 11,651
Tdark 8 | 6,593
Tchem 3 | 1,388

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
decreased bone mineral content 1 | 151
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
limb grasping 1 | 41

Disease

Carcinoma 18 | 11,493
osteosarcoma 17 | 7,950
ovarian cancer 16 | 8,520
atypical teratoid / rhabdoid tumor 13 | 5,112
medulloblastoma, large-cell 13 | 6,241
glioblastoma 12 | 5,792
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
lung cancer 9 | 4,740
malignant mesothelioma 9 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
psoriasis 8 | 6,694
Astrocytoma, Pilocytic 7 | 3,081
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
Pick disease 6 | 1,894
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
subependymal giant cell astrocytoma 6 | 2,287
Breast cancer 5 | 3,578
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Rheumatoid arthritis 4 | 1,191
breast carcinoma 4 | 1,638
interstitial cystitis 4 | 2,312
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
Congenital myasthenic syndrome 6 3 | 17
Prostatic Neoplasms 3 | 495
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
hereditary spastic paraplegia 3 | 318
lung carcinoma 3 | 2,843
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
spina bifida 3 | 1,074
Acidosis, Lactic 2 | 97
Bipolar Disorder 2 | 666
Cognitive delay 2 | 608
Epilepsy 2 | 792
Global developmental delay 2 | 608
Lactic acidemia 2 | 95
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Polycystic ovary syndrome 2 | 360
Seizures 2 | 596
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
medulloblastoma 2 | 720
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
tuberculosis 2 | 2,010
Acquired metabolic disease 1 | 336
Amyotrophic lateral sclerosis 1 | 451
Atopic dermatitis 1 | 952
Concave bridge of nose 1 | 195
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Endometrial cancer 1 | 311
Failure to gain weight 1 | 365
Frontal bossing 1 | 157
Gait Ataxia 1 | 51
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Heart disease 1 | 306
Infantile onset 1 | 238
Leukemia 1 | 104
Liver cancer 1 | 604
Maple syrup urine disease 1 | 24
Nephrolithiasis 1 | 56
Neurodevelopmental Disorders 1 | 70
Parkinson's disease 1 | 392
Pediatric failure to thrive 1 | 365
Poor growth 1 | 114
Prostate cancer 1 | 175
Pyruvate decarboxylase deficiency 1 | 16
Turner syndrome 1 | 28
Very poor growth 1 | 114
cystic fibrosis and chronic rhinosinusitis 1 | 214
head and neck cancer 1 | 271
limb girdle muscular dystrophy 2B 1 | 40
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 3 months 1 | 179
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Enzyme 20 | 4,145
Non-IDG 10 | 12,091
Kinase 1 | 634

PANTHER Protein Class (2)

kinase inhibitor 31 | 31
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein phosphatase 1E PPM1E Tbio Enzyme -0.97004 9.49 44
Ankyrin repeat domain-containing protein 49 ANKRD49 Tbio Non-IDG -1.77333 58.8 74
Zinc finger MYM-type protein 5 ZMYM5 Tdark Non-IDG -0.99018 9.06 29
Protein phosphatase 1B PPM1B Tchem Enzyme -1.55136 36.3 200
Cyclin-dependent kinase 2-associated protein 1 CDK2AP1 Tbio Enzyme -2.04718 111.1 118
Protein phosphatase 1L PPM1L Tbio Enzyme -0.74923 6.69 111
Protein phosphatase 1A PPM1A Tchem Enzyme -1.65009 48.7 323
Protein phosphatase 1K, mitochondrial PPM1K Tbio Enzyme -1.23460 16.5 103
Protein phosphatase 1D PPM1D Tchem Enzyme -2.14384 181.8 218
Cyclin-dependent kinase 2-associated protein 2 CDK2AP2 Tbio Enzyme -0.82992 7.79 129