Development Level

Tbio 39 | 11,651
Tdark 9 | 6,593
Tchem 7 | 1,388

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
embryonic lethality prior to o... 3 | 239
abnormal neural tube closure 2 | 46
female infertility 2 | 60
male infertility 2 | 123
pale yolk sac 2 | 25
pallor 2 | 34
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta size 1 | 20
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
small kidney 1 | 16
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 31 | 8,520
Carcinoma 30 | 11,493
osteosarcoma 30 | 7,950
medulloblastoma, large-cell 25 | 6,241
lung cancer 21 | 4,740
psoriasis 21 | 6,694
Cancer 17 | 2,499
glioblastoma 17 | 5,792
group 3 medulloblastoma 17 | 4,104
malignant mesothelioma 15 | 3,232
non-small cell lung cancer 15 | 2,890
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 14 | 4,679
Breast cancer 13 | 3,578
adult high grade glioma 13 | 3,801
lung adenocarcinoma 13 | 2,716
primitive neuroectodermal tumor 13 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
invasive ductal carcinoma 12 | 2,951
subependymal giant cell astrocytoma 10 | 2,287
breast carcinoma 9 | 1,638
oligodendroglioma 9 | 2,850
Pick disease 8 | 1,894
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
Astrocytoma, Pilocytic 7 | 3,081
Atopic dermatitis 7 | 952
Multiple myeloma 7 | 1,332
adrenocortical carcinoma 7 | 1,428
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
nasopharyngeal carcinoma 7 | 1,058
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Kidney cancer 6 | 2,613
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
dermatomyositis 6 | 966
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
lung carcinoma 6 | 2,843
pituitary cancer 6 | 1,972
Duchenne muscular dystrophy 5 | 601
Schizophrenia 5 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
ulcerative colitis 5 | 1,819
Amyotrophic lateral sclerosis 4 | 451
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Endometriosis 4 | 540
Liver Cirrhosis, Experimental 4 | 769
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
Carcinoma, Hepatocellular 3 | 228
Glycogen storage disease 3 | 39
Liver carcinoma 3 | 240
Polycystic ovary syndrome 3 | 360
Type 2 diabetes mellitus 3 | 272
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074
tuberculosis and treatment for 6 months 3 | 409
Colonic Neoplasms 2 | 142
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Diarrhea 2 | 253
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hepatomegaly 2 | 285
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Mental Depression 2 | 333
Muscle Weakness 2 | 170
Myocardial Ischemia 2 | 169
Peripheral vascular disease 2 | 87
Poor growth 2 | 114
Prenatal onset 2 | 139
Progressive disorder 2 | 142
Prostatic Neoplasms 2 | 495
Recurrent respiratory infections 2 | 141
Very poor growth 2 | 114
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
chronic lymphosyte leukemia 2 | 204

Tissue

Endocrine System 54 | 18,159
Digestive Tract 53 | 17,369
Liver and Pancreas 53 | 16,750
Nervous System 53 | 16,725
Skin and soft tissues 53 | 17,230
Male tissues 52 | 17,142
Blood and immune system 51 | 16,909
Female tissues 51 | 17,400
Respiratory system 51 | 16,393
Urinary Tract 50 | 16,678
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 17 | 4,145
Kinase 2 | 634

PANTHER Protein Class (2)

kinase activator 55 | 55
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cell cycle checkpoint control protein RAD9B RAD9B Tdark Non-IDG -0.07767 1.44 35
Cyclin-I2 CCNI2 Tdark Non-IDG 0.12 0.65 75
Cyclin-L2 CCNL2 Tbio Non-IDG -2.03003 102.4 104
Adenosine deaminase domain-containing protein 2 ADAD2 Tdark Enzyme 0.23 0.43 53
Cyclin-L1 CCNL1 Tbio Non-IDG -0.82661 6.96 183
Cell cycle checkpoint control protein RAD9A RAD9A Tbio Non-IDG -2.15330 141.0 919
MOB kinase activator 1B MOB1B Tbio Enzyme -0.76662 5.02 235
MOB kinase activator 2 MOB2 Tbio Enzyme -1.43069 27.7 122
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.14393 1189.3 1251
C-Jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 Tbio Enzyme -2.85543 697.4 180