Development Level

Tbio 44 | 10,625
Tchem 16 | 1,890
Tdark 12 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 5 | 633
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal neural tube closure 1 | 37
abnormal placenta size 1 | 10
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
female infertility 1 | 34
increased circulating HDL chol... 1 | 63
increased exploration in new e... 1 | 56
increased or absent threshold ... 1 | 128
male infertility 1 | 62
pale yolk sac 1 | 12
pallor 1 | 13
urinary bladder obstruction 1 | 2

Disease

osteosarcoma 41 | 7,933
ovarian cancer 41 | 8,484
medulloblastoma, large-cell 33 | 6,234
psoriasis 29 | 6,685
glioblastoma 26 | 5,572
lung cancer 26 | 4,466
Cancer 18 | 2,346
atypical teratoid / rhabdoid tumor 18 | 4,369
non-small cell lung cancer 18 | 2,798
primitive neuroectodermal tumor 18 | 3,031
Breast cancer 17 | 3,094
malignant mesothelioma 17 | 3,162
lung adenocarcinoma 16 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
invasive ductal carcinoma 15 | 2,950
oligodendroglioma 15 | 2,849
ependymoma 14 | 2,514
pediatric high grade glioma 14 | 2,712
subependymal giant cell astrocytoma 14 | 2,287
astrocytic glioma 11 | 2,241
group 4 medulloblastoma 11 | 1,875
pilocytic astrocytoma 11 | 3,086
Multiple myeloma 10 | 1,327
astrocytoma 10 | 1,493
breast carcinoma 10 | 1,614
ductal carcinoma in situ 10 | 1,745
Pick disease 9 | 1,893
adult high grade glioma 9 | 2,148
colon cancer 9 | 1,475
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
posterior fossa group A ependymoma 9 | 1,511
adrenocortical carcinoma 8 | 1,427
dermatomyositis 8 | 933
group 3 medulloblastoma 8 | 2,254
juvenile dermatomyositis 8 | 1,189
nasopharyngeal carcinoma 8 | 1,056
pancreatic cancer 8 | 2,300
pituitary cancer 8 | 1,972
sonic hedgehog group medulloblastoma 8 | 1,482
tuberculosis 8 | 1,557
Atopic dermatitis 7 | 944
Carcinoma 7 | 2,147
Rheumatoid Arthritis 7 | 1,160
acute quadriplegic myopathy 7 | 1,157
atypical teratoid/rhabdoid tumor 7 | 1,095
cystic fibrosis 7 | 1,665
cutaneous lupus erythematosus 6 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung carcinoma 6 | 2,844
medulloblastoma 6 | 1,524
primary Sjogren syndrome 6 | 789
primary pancreatic ductal adenocarcinoma 6 | 1,271
tuberculosis and treatment for 6 months 6 | 686
ulcerative colitis 6 | 2,087
Duchenne muscular dystrophy 5 | 602
Endometriosis 5 | 535
Waldenstrons macroglobulinemia 5 | 765
diabetes mellitus 5 | 1,663
interstitial cystitis 5 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
progressive supranuclear palsy 5 | 674
IGA Glomerulonephritis 4 | 454
spina bifida 4 | 1,064
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 431
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Glycogen storage disease 3 | 37
Liver carcinoma 3 | 217
Peripheral vascular disease 3 | 90
Polycystic Ovary Syndrome 3 | 332
Prostatic Neoplasms 3 | 471
active Crohn's disease 3 | 918
active ulcerative colitis 3 | 477
acute myeloid leukemia 3 | 780
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic lymphosyte leukemia 3 | 232
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
hepatocellular carcinoma 3 | 532
interstitial lung disease 3 | 291
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group B ependymoma 3 | 1,530
sarcoidosis 3 | 358
Animal Mammary Neoplasms 2 | 136
Cervical cancer 2 | 21
Chronic Lymphocytic Leukemia 2 | 242
Colonic Neoplasms 2 | 126
Down syndrome 2 | 548
Lung Neoplasms 2 | 171
Mammary Neoplasms 2 | 410
Mammary Neoplasms, Experimental 2 | 150
Myocardial Ischemia 2 | 169
Small cell neuroendocrine carcinoma 2 | 2
Type 2 diabetes mellitus 2 | 189
Vaginal cancer 2 | 3
mucosa-associated lymphoid tissue lymphoma 2 | 480
ovarian neoplasm 2 | 97
pancreatic carcinoma 2 | 567
Motor neuron disease 1 | 39

Tissue

Blood and immune system 71 | 17,995
Female tissues 71 | 18,647
Cardiovascular System 70 | 17,958
Digestive Tract 70 | 18,473
Endocrine System 70 | 18,512
Liver and Pancreas 70 | 18,136
Male tissues 70 | 17,969
Nervous System 70 | 18,561
Skin and soft tissues 70 | 18,115
Urinary Tract 70 | 18,444
Respiratory system 69 | 17,484

Target Family

Non-IDG 53 | 11,971
Enzyme 17 | 4,146
Kinase 2 | 634

PANTHER Protein Class (2)

kinase activator 72 | 72
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Zinc finger RNA-binding protein 2 ZFR2 Tdark Non-IDG -0.02511 0.87 5
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.82506 66.9 35
WD repeat and FYVE domain-containing protein 1 WDFY1 Tbio Non-IDG -0.67020 4.80 91
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform PHKA1 Tchem Kinase -1.16884 14.3 67