Development Level

Tbio 79 | 11,445
Tdark 9 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal abdominal wall morpho... 1 | 1
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
absent vibrissae 1 | 12
cleft palate 1 | 8
corneal opacity 1 | 32
corneal vascularization 1 | 6
cyanosis 1 | 7
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
enlarged urinary bladder 1 | 8
eyelids fail to open 1 | 3
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased hemoglobin content 1 | 45
long tibia 1 | 25
narrow eye opening 1 | 12
rib fusion 1 | 1
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 39 | 11,493
medulloblastoma, large-cell 26 | 6,241
psoriasis 24 | 6,694
osteosarcoma 23 | 7,950
ovarian cancer 23 | 8,520
glioblastoma 20 | 5,792
lung cancer 20 | 4,740
atypical teratoid / rhabdoid tumor 19 | 5,112
malignant mesothelioma 19 | 3,232
Breast cancer 15 | 3,578
Cancer 15 | 2,499
cystic fibrosis 15 | 1,696
invasive ductal carcinoma 15 | 2,951
primitive neuroectodermal tumor 14 | 3,035
Astrocytoma, Pilocytic 13 | 3,081
non-small cell lung cancer 13 | 2,890
adult high grade glioma 12 | 3,801
ependymoma 12 | 4,679
group 3 medulloblastoma 12 | 4,104
Cleft Palate 11 | 271
ductal carcinoma in situ 10 | 1,745
oligodendroglioma 10 | 2,850
breast carcinoma 9 | 1,638
interstitial cystitis 9 | 2,312
lung adenocarcinoma 9 | 2,716
Autosomal recessive predisposition 8 | 1,442
Cognitive delay 8 | 608
Craniofacial Abnormalities 8 | 151
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
astrocytic glioma 8 | 2,597
cutaneous lupus erythematosus 8 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pituitary cancer 8 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Cleft Lip 6 | 141
Muscle hypotonia 6 | 571
Sensorineural Hearing Loss (disorder) 6 | 284
Uranostaphyloschisis 6 | 167
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
medulloblastoma 6 | 720
pancreatic cancer 6 | 2,398
pediatric high grade glioma 6 | 1,064
Bipolar Disorder 5 | 666
Epilepsy 5 | 792
Lung diseases 5 | 50
Microphthalmia 5 | 76
Schizophrenia 5 | 1,160
Seizures 5 | 596
Syndactyly 5 | 88
Tooth agenesis 5 | 44
gastric carcinoma 5 | 807
spina bifida 5 | 1,074
Abnormally small eyeball 4 | 97
Agenesis of corpus callosum 4 | 83
Autistic Disorder 4 | 364
Congenital heart disease 4 | 93
Congenital hypoplasia of penis 4 | 176
Cryptorchidism 4 | 296
Decreased size of eyeball 4 | 97
Intellectual disability 4 | 1,016
Microphthalmos 4 | 100
Obesity 4 | 678
Split hand-foot malformation 4 | 18
Ventricular Septal Defects 4 | 119
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
lung carcinoma 4 | 2,843
subependymal giant cell astrocytoma 4 | 2,287
Barrett's esophagus 3 | 182
Cataract 3 | 297
Conductive hearing loss 3 | 123
Constipation 3 | 181
Dull intelligence 3 | 645
Glaucoma 3 | 239
Holoprosencephaly 3 | 56
Lens Opacities 3 | 231
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Myopia 3 | 176
Orbital separation excessive 3 | 244
Periventricular nodular heterotopia 3 | 30
Poor school performance 3 | 645
Prostate cancer 3 | 175
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Spastic Quadriplegia 3 | 42
Strabismus 3 | 270
Tetralogy of Fallot 3 | 63
Velocardiofacial syndrome 3 | 46
aldosterone-producing adenoma 3 | 665
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group A ependymoma 3 | 468
sonic hedgehog group medulloblastoma 3 | 467
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 79 | 18,159
Digestive Tract 68 | 17,369
Skin and soft tissues 66 | 17,230
Female tissues 62 | 17,400
Blood and immune system 60 | 16,909
Male tissues 59 | 17,142
Nervous System 58 | 16,725
Liver and Pancreas 56 | 16,750
Urinary Tract 51 | 16,678
Respiratory system 50 | 16,393
Cardiovascular System 36 | 15,192

Target Family

Transcription Factor 82 | 1,400
Non-IDG 6 | 12,091

PANTHER Protein Class (2)

homeodomain transcription fact... 88 | 88
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Hox-C5 HOXC5 Tbio Transcription Factor -1.08912 11.9 114
One cut domain family member 2 ONECUT2 Tbio Transcription Factor -2.25163 169.5 107
Cone-rod homeobox protein CRX Tbio Transcription Factor -2.44826 272.0 185
Homeobox protein Nkx-2.6 NKX2-6 Tbio Transcription Factor -3.04651 1092.2 134
BarH-like 2 homeobox protein BARHL2 Tbio Transcription Factor -0.91713 9.51 53
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Homeobox protein BarH-like 1 BARX1 Tbio Transcription Factor -1.51202 31.9 202
Homeobox protein CDX-2 CDX2 Tbio Transcription Factor -2.91273 837.0 699
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141