Development Level

Tbio 38 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
decreased bone mineral content 2 | 151
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 25 | 11,493
glioblastoma 23 | 5,792
medulloblastoma, large-cell 23 | 6,241
ovarian cancer 23 | 8,520
osteosarcoma 22 | 7,950
ependymoma 19 | 4,679
psoriasis 19 | 6,694
atypical teratoid / rhabdoid tumor 18 | 5,112
Astrocytoma, Pilocytic 15 | 3,081
adult high grade glioma 15 | 3,801
Breast cancer 14 | 3,578
lung carcinoma 14 | 2,843
Pick disease 13 | 1,894
group 3 medulloblastoma 13 | 4,104
subependymal giant cell astrocytoma 13 | 2,287
primitive neuroectodermal tumor 12 | 3,035
invasive ductal carcinoma 11 | 2,951
oligodendroglioma 11 | 2,850
pancreatic cancer 11 | 2,398
lung cancer 10 | 4,740
astrocytic glioma 9 | 2,597
juvenile dermatomyositis 9 | 1,187
non-small cell lung cancer 9 | 2,890
pituitary cancer 9 | 1,972
active Crohn's disease 8 | 922
astrocytoma 8 | 1,146
colon cancer 8 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
ulcerative colitis 8 | 1,819
active ulcerative colitis 7 | 764
breast carcinoma 7 | 1,638
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
primary Sjogren syndrome 7 | 735
sarcoidosis 7 | 370
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
malignant mesothelioma 6 | 3,232
Duchenne muscular dystrophy 5 | 601
Liver Cirrhosis, Experimental 5 | 769
ductal carcinoma in situ 5 | 1,745
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis 5 | 2,010
Cancer 4 | 2,499
Rheumatoid arthritis 4 | 1,191
acute quadriplegic myopathy 4 | 1,158
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
nasopharyngeal carcinoma 4 | 1,058
Charcot-Marie-Tooth disease dominant intermediate F 3 | 3
Cholera 3 | 34
Depressive disorder 3 | 409
Fibrous dysplasia 3 | 15
Intellectual disability 3 | 1,016
McCune Albright syndrome 3 | 19
Multiple myeloma 3 | 1,332
Neuropathy 3 | 261
Pseudohypoparathyroidism 3 | 18
Schizophrenia 3 | 1,160
Substance Withdrawal Syndrome 3 | 55
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
hepatocellular carcinoma 3 | 547
non primary Sjogren syndrome sicca 3 | 891
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
urothelial carcinoma 3 | 318
Atopic dermatitis 2 | 952
Big calvaria 2 | 147
Bipolar Disorder 2 | 666
Cerebral atrophy 2 | 178
Colorectal Neoplasms 2 | 243
Congenital Heart Defects 2 | 58
Congenital stationary night blindness 2 | 29
Epilepsy 2 | 792
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Hyperreflexia 2 | 209
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Kidney cancer 2 | 2,613
Melanoma 2 | 711
Mental Depression 2 | 333
Myocardial Ischemia 2 | 169
Neurodegenerative disease 2 | 414
Paraplegia 2 | 74
Paresthesia 2 | 32
Polycystic ovary syndrome 2 | 360
Retinal Detachment 2 | 51
Seizures 2 | 596
Skin cancer 2 | 469
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
limb girdle muscular dystrophy 2I 2 | 32
pancreatic carcinoma 2 | 562

Tissue

Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Nervous System 40 | 16,725
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Respiratory system 39 | 16,393
Urinary Tract 39 | 16,678
Male tissues 38 | 17,142
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 43 | 12,091

PANTHER Protein Class (2)

heterotrimeric G-protein 43 | 43
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Guanylate-binding protein 7 GBP7 Tdark Non-IDG -0.45484 2.62 54
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 GNG10 Tdark Non-IDG 0.16 0.62 18
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 GNG5 Tbio Non-IDG -0.57807 4.05 87
Guanine nucleotide-binding protein G(t) subunit alpha-3 GNAT3 Tbio Non-IDG -2.28370 189.3 111
RING finger protein 112 RNF112 Tbio Non-IDG -2.36685 229.7 118