Development Level

Tbio 58 | 11,651
Tdark 12 | 6,593
Tchem 6 | 1,388
Tclin 1 | 612

IMPC Phenotype

increased lean body mass 3 | 172
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal gait 2 | 69
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal vocalization 1 | 21
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased granulocyte number 1 | 6
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
enlarged gallbladder 1 | 2
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
male infertility 1 | 123
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 65 | 11,493
osteosarcoma 48 | 7,950
medulloblastoma, large-cell 38 | 6,241
ovarian cancer 36 | 8,520
atypical teratoid / rhabdoid tumor 33 | 5,112
ependymoma 33 | 4,679
glioblastoma 33 | 5,792
psoriasis 29 | 6,694
lung cancer 28 | 4,740
Astrocytoma, Pilocytic 26 | 3,081
adult high grade glioma 25 | 3,801
Breast cancer 24 | 3,578
Kidney cancer 24 | 2,613
non-small cell lung cancer 24 | 2,890
group 3 medulloblastoma 23 | 4,104
invasive ductal carcinoma 22 | 2,951
lung carcinoma 22 | 2,843
malignant mesothelioma 21 | 3,232
interstitial cystitis 18 | 2,312
subependymal giant cell astrocytoma 18 | 2,287
lung adenocarcinoma 17 | 2,716
primitive neuroectodermal tumor 17 | 3,035
oligodendroglioma 16 | 2,850
ulcerative colitis 16 | 1,819
astrocytic glioma 14 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
Pick disease 12 | 1,894
ductal carcinoma in situ 12 | 1,745
group 4 medulloblastoma 12 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
primary Sjogren syndrome 10 | 735
Autosomal recessive predisposition 9 | 1,442
Intellectual disability 9 | 1,016
Liver cancer 9 | 604
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pancreatic cancer 9 | 2,398
pituitary cancer 9 | 1,972
tuberculosis 9 | 2,010
Cancer 8 | 2,499
Melanoma 8 | 711
astrocytoma 8 | 1,146
cutaneous lupus erythematosus 8 | 1,057
spina bifida 8 | 1,074
Bipolar Disorder 7 | 666
Schizophrenia 7 | 1,160
Short stature 7 | 531
aldosterone-producing adenoma 7 | 665
colon cancer 7 | 1,478
dermatomyositis 7 | 966
juvenile dermatomyositis 7 | 1,187
Skin cancer 6 | 469
mucosa-associated lymphoid tissue lymphoma 6 | 484
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Aarskog syndrome 5 | 12
Acquired scoliosis 5 | 281
Chronic Lymphocytic Leukemia 5 | 262
Curvature of spine 5 | 282
Epilepsy 5 | 792
Rheumatoid arthritis 5 | 1,191
active Crohn's disease 5 | 922
pediatric high grade glioma 5 | 1,064
urothelial carcinoma 5 | 318
Cognitive delay 4 | 608
Downward slant of palpebral fissure 4 | 158
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Poor school performance 4 | 645
Strabismus 4 | 270
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
interstitial lung disease 4 | 298
progressive supranuclear palsy 4 | 676
sarcoidosis 4 | 370
Atopic dermatitis 3 | 952
Byzanthine arch palate 3 | 194
Crohn's disease 3 | 321
Down syndrome 3 | 499
Endometriosis 3 | 540
Hepatomegaly 3 | 285
Infantile onset 3 | 238
Liver Cirrhosis, Experimental 3 | 769
Major Depressive Disorder 3 | 301
Pectus excavatum 3 | 100
Seizures 3 | 596
Unipolar Depression 3 | 250
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
gastric carcinoma 3 | 807
hereditary spastic paraplegia 3 | 318
nasopharyngeal carcinoma 3 | 1,058
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 77 | 17,369
Endocrine System 77 | 18,159
Female tissues 77 | 17,400
Liver and Pancreas 77 | 16,750
Skin and soft tissues 77 | 17,230
Urinary Tract 77 | 16,678
Cardiovascular System 76 | 15,192
Male tissues 76 | 17,142
Nervous System 76 | 16,725
Blood and immune system 75 | 16,909
Respiratory system 75 | 16,393

Target Family

Non-IDG 58 | 12,091
Enzyme 19 | 4,145

PANTHER Protein Class (2)

guanyl-nucleotide exchange fac... 77 | 77
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..