Development Level

Tbio 16 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
decreased urine magnesium leve... 1 | 3
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
male infertility 1 | 123
small testis 1 | 58

Disease

Carcinoma 17 | 11,493
ovarian cancer 14 | 8,520
osteosarcoma 11 | 7,950
Kidney cancer 9 | 2,613
glioblastoma 8 | 5,792
psoriasis 8 | 6,694
group 3 medulloblastoma 7 | 4,104
atypical teratoid / rhabdoid tumor 6 | 5,112
medulloblastoma, large-cell 6 | 6,241
lung cancer 5 | 4,740
primitive neuroectodermal tumor 5 | 3,035
Breast cancer 4 | 3,578
ependymoma 4 | 4,679
Autosomal recessive predisposition 3 | 1,442
Liver cancer 3 | 604
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
Amyotrophic lateral sclerosis 2 | 451
Apraxia 2 | 26
Astrocytoma, Pilocytic 2 | 3,081
Convex nasal ridge 2 | 37
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Intellectual disability 2 | 1,016
Male infertility 2 | 206
Neurodegenerative disease 2 | 414
Perlman syndrome 2 | 9
Slow progression 2 | 89
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
dermatomyositis 2 | 966
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
Abnormal upper motor neuron morphology 1 | 11
Acute stress disorder 1 | 6
Aicardi-Goutieres syndrome 1 | 19
Ataxia telangiectasia 1 | 34
Ataxia, Appendicular 1 | 25
Axonal degeneration 1 | 7
Babinski Reflex 1 | 100
Blepharoptosis 1 | 231
Cerebral calcification 1 | 43
Congenital pes cavus 1 | 88
Death in childhood 1 | 14
Decreased motor NCV 1 | 22
Decreased platelet count 1 | 111
Degeneration of anterior horn cells 1 | 7
Degenerative brain disorder 1 | 100
Deglutition Disorders 1 | 132
DiGeorge syndrome 1 | 47
Dilated ventricles (finding) 1 | 121
Dyskeratosis congenita 1 | 24
Fanconi anemia 1 | 56
Friedreich ataxia 1 | 24
Generalized amyotrophy 1 | 20
Global developmental delay, severe 1 | 47
Gowers sign 1 | 24
Gowers sign present 1 | 24
Heavy chain disease 1 | 6
Hemiplegia and hemiparesis 1 | 38
Highly variable severity 1 | 157
Influenza 1 | 142
Kyphoscoliosis deformity of spine 1 | 60
Leukodystrophy 1 | 55
Long Qt Syndrome 2 1 | 5
Mucoepidermoid carcinoma 1 | 26
Muscle Cramp 1 | 55
Nager acrofacial dysostosis 1 | 21
Nystagmus, End-Position 1 | 12
Peripheral Neuropathy 1 | 134
Polyhydramnios 1 | 108
Polyneuropathy 1 | 64
Pontocerebellar Hypoplasia Type 2 1 | 5
Pontocerebellar Hypoplasia Type 2C 1 | 1
Pontocerebellar Hypoplasia, Type 2C 1 | 1
Profound intellectual disabilities 1 | 31
Progressive microcephaly 1 | 32
Pyramidal sign 1 | 29
Retinitis pigmentosa 59 1 | 11
Seckel syndrome 1 | 34
Severe psychomotor retardation 1 | 47
Spastic Ataxia 1 | 18
Subacute thyroiditis 1 | 3
Supratentorial atrophy 1 | 94
Thrombocytopenia 1 | 197
Vision Disorders 1 | 6
Werner syndrome 1 | 29
Wilms Tumor 1 | 28
non-small cell lung carcinoma 1 | 317
tick-borne encephalitis 1 | 14

Tissue

Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Blood and immune system 21 | 16,909
Nervous System 21 | 16,725
Urinary Tract 21 | 16,678

Target Family

Enzyme 15 | 4,145
Non-IDG 7 | 12,091

PANTHER Protein Class (2)

endoribonuclease 22 | 22
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Probable helicase with zinc finger domain HELZ Tbio Enzyme -1.50209 22.1 63
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
Helicase with zinc finger domain 2 HELZ2 Tdark Enzyme -0.50849 4.27 30
Protein ZGRF1 ZGRF1 Tdark Non-IDG 0.50 0.58 99
tRNA-splicing endonuclease subunit Sen34 TSEN34 Tdark Enzyme -0.75841 5.30 26
RNA helicase Mov10l1 MOV10L1 Tbio Enzyme -0.73306 5.20 57
DIS3-like exonuclease 1 DIS3L Tdark Enzyme -0.68418 3.89 94
Ribonuclease H2 subunit A RNASEH2A Tbio Enzyme -2.17825 146.7 124
Ribonuclease P protein subunit p20 POP7 Tbio Enzyme -0.86962 7.33 47