Development Level

Tbio 14 | 10,625
Tchem 2 | 1,890

IMPC Term

increased circulating HDL chol... 2 | 63
abnormal retina morphology 1 | 100
decreased bone mineral density 1 | 126
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased circulating choleste... 1 | 53
preweaning lethality, complete... 1 | 633

Disease

osteosarcoma 12 | 7,933
Cancer 8 | 2,346
psoriasis 8 | 6,685
ovarian cancer 7 | 8,484
malignant mesothelioma 6 | 3,162
medulloblastoma, large-cell 6 | 6,234
Breast cancer 5 | 3,094
Peripheral Neuropathy 5 | 303
glioblastoma 5 | 5,572
group 3 medulloblastoma 5 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
atypical teratoid / rhabdoid tumor 4 | 4,369
lung cancer 4 | 4,466
primitive neuroectodermal tumor 4 | 3,031
Cockayne syndrome 3 | 54
Colorectal adenoma 3 | 15
Fanconi's anemia 3 | 50
Xeroderma pigmentosum 3 | 41
colon cancer 3 | 1,475
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
invasive ductal carcinoma 3 | 2,950
lung adenocarcinoma 3 | 2,713
non primary Sjogren syndrome sicca 3 | 840
non-small cell lung cancer 3 | 2,798
pediatric high grade glioma 3 | 2,712
sonic hedgehog group medulloblastoma 3 | 1,482
Adenomatous Polyposis Coli 2 | 10
Arsenic Poisoning 2 | 59
Bloom syndrome 2 | 30
Carcinoma 2 | 2,147
Colitis 2 | 46
Colorectal Neoplasms 2 | 217
Combined Cellular And Humoral Immune Defects With Granulomas 2 | 2
Crohn's disease 2 | 304
Endometriosis 2 | 535
Histiocytic medullary reticulosis (disorder) 2 | 3
IGA Glomerulonephritis 2 | 454
Lymphopenia 2 | 35
Lynch syndrome 2 | 33
Neoplasm Metastasis 2 | 138
Neoplasms, Germ Cell and Embryonal 2 | 13
Omenn Syndrome 2 | 14
Photosensitive trichothiodystrophy 2 | 24
Reticuloendotheliosis, familial, with eosinophilia 2 | 3
Severe Combined Immunodeficiency 2 | 46
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, NK Cell-Positive 2 | 2
Stomach Neoplasms 2 | 282
Testicular Neoplasms 2 | 5
Waldenstrons macroglobulinemia 2 | 765
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 532
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
nasopharyngeal carcinoma 2 | 1,056
ulcerative colitis 2 | 2,087
Adenocarcinoma of lung (disorder) 1 | 48
Adenoma 1 | 165
Aicardi-Goutieres syndrome 1 | 18
Amyotrophic Lateral Sclerosis 1 | 431
Aplastic anemia 1 | 18
Arthritis, Experimental 1 | 39
Bladder Neoplasm 1 | 109
Calcific tendinitis 1 | 7
Cataract 1 | 104
Colon Carcinoma 1 | 25
Deglutition Disorders 1 | 4
Endometrial carcinoma 1 | 18
Familial adenomatous polyposis 1 | 31
Fragile X syndrome 1 | 31
Gaucher disease type 1 1 | 171
Goiter 1 | 27
Juvenile polyposis syndrome 1 | 7
Mammary Neoplasms 1 | 410
Melanoma 1 | 261
Menopause present (finding) 1 | 20
Microcephaly 1 | 149
Movement Disorders 1 | 21
Neoplastic Syndromes, Hereditary 1 | 48
Neurodegenerative disease 1 | 383
Neutropenia 1 | 78
Non-alcoholic Fatty Liver Disease 1 | 40
Oligospermia 1 | 30
Peutz-Jeghers syndrome 1 | 23
Pilomatrixoma 1 | 11
Pontocerebellar Hypoplasia Type 2 1 | 4
Pontocerebellar hypoplasia 1 | 29
Prostate cancer 1 | 172
Restless legs syndrome 1 | 28
Uterine Cervical Neoplasm 1 | 21
Vision Disorders 1 | 5
Weight Gain 1 | 87
Werner syndrome 1 | 29
active Crohn's disease 1 | 918
atypical teratoid/rhabdoid tumor 1 | 1,095
hereditary spastic paraplegia 1 | 313
medulloblastoma 1 | 1,524
non-small cell lung carcinoma 1 | 413
permanent atrial fibrillation 1 | 44
sarcoidosis 1 | 358
tuberculosis 1 | 1,557
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 16 | 17,995
Endocrine System 16 | 18,512
Female tissues 16 | 18,647
Liver and Pancreas 16 | 18,136
Male tissues 16 | 17,969
Nervous System 16 | 18,561
Urinary Tract 16 | 18,444
Cardiovascular System 15 | 17,958
Digestive Tract 15 | 18,473
Respiratory system 15 | 17,484
Skin and soft tissues 15 | 18,115

Target Family

Enzyme 13 | 4,146
Non-IDG 2 | 11,971
Epigenetic 1 | 242

PANTHER Protein Class (2)

endodeoxyribonuclease 16 | 16
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
actin binding motor protein 60 | 60
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.00063 1061.1 65
Deoxyribonuclease-2-beta DNASE2B Tbio Enzyme -1.48231 31.2 70
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.28778 1908.4 279
Exonuclease 1 EXO1 Tbio Enzyme -2.58414 403.9 226
tRNA-splicing endonuclease subunit Sen2 TSEN2 Tbio Enzyme -1.00789 10.1 118
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.81623 699.9 239
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.81894 63.2 139
Flap endonuclease 1 FEN1 Tchem Enzyme -2.72054 533.8 332
V(D)J recombination-activating protein 2 RAG2 Tbio Epigenetic -2.88477 764.3 183
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.65841 46.9 91