Development Level

Tbio 14 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal retina morphology 1 | 71
absent spleen 1 | 3
decreased bone mineral density 1 | 126
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 11 | 7,950
Carcinoma 8 | 11,493
group 3 medulloblastoma 8 | 4,104
Cancer 7 | 2,499
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Cockayne syndrome 4 | 60
Xeroderma pigmentosum group G 4 | 16
lung cancer 4 | 4,740
primitive neuroectodermal tumor 4 | 3,035
Bloom syndrome 3 | 29
Xeroderma pigmentosum 3 | 43
adult high grade glioma 3 | 3,801
colon cancer 3 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
Adenomatous Polyposis Coli 2 | 16
Arsenic Poisoning 2 | 62
Basal cell carcinoma 2 | 54
Basal cell nevi 2 | 23
Cataract 2 | 297
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Colorectal adenoma 2 | 15
Crohn's disease 2 | 321
Decreased platelet count 2 | 111
Dry skin 2 | 75
Electroencephalogram abnormal 2 | 101
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Enophthalmos 2 | 75
Failure to gain weight 2 | 365
Fanconi anemia 2 | 56
Fever 2 | 138
Genetic Predisposition to Disease 2 | 27
Global developmental delay 2 | 608
Hypogonadism 2 | 173
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Lens Opacities 2 | 231
Low Vision 2 | 174
Lynch syndrome 2 | 35
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Neoplasm Metastasis 2 | 168
Neoplasms, Germ Cell and Embryonal 2 | 15
Pediatric failure to thrive 2 | 365
Peripheral Nervous System Diseases 2 | 52
Peripheral Neuropathy 2 | 134
Photosensitivity of skin 2 | 51
Sensorineural Hearing Loss (disorder) 2 | 284
Short stature 2 | 531
Small head 2 | 374
Stomach Neoplasms 2 | 300
Sunken eyes 2 | 63
Testicular Neoplasms 2 | 6
Thrombocytopenia 2 | 197
Visual Impairment 2 | 174
Waldenstrons macroglobulinemia 2 | 765
XFE progeroid syndrome 2 | 3
Xeroderma pigmentosum group F 2 | 22
Xerosis 2 | 75
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
nasopharyngeal carcinoma 2 | 1,058
ulcerative colitis 2 | 1,819
Almond-shaped eyes 1 | 23
Atrophic condition of skin 1 | 25
Chromosome Aberrations 1 | 16
Colorectal Adenomatous Polyposis, Autosomal Recessive 1 | 1
Cystic nephroma 1 | 5
High pitched voice 1 | 23
MYH-associated polyposis 1 | 1
Multiple colonic adenomatous polyps 1 | 3
Papule 1 | 43
Peripheral demyelinating neuropathy 1 | 7
Pneumonia, Interstitial 1 | 5
Poikiloderma 1 | 14
Precociously senile appearance 1 | 18
Prominent metopic ridge 1 | 15
Pyridoxine-responsive sideroblastic anemia 1 | 17
Radial aplasia/hypoplasia 1 | 29
Rigid spine muscular dystrophy 1 1 | 14
Splayed metaphyses 1 | 19
Squamous cell carcinoma of skin 1 | 11
Thumb aplasia 1 | 16
Vitelliform macular dystrophy 1 | 14
alcohol use disorder 1 | 12

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192

Target Family

Enzyme 13 | 4,145
Non-IDG 2 | 12,091

PANTHER Protein Class (2)

endodeoxyribonuclease 15 | 15
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.86910 750.8 255
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.05993 1094.2 84
Exonuclease 1 EXO1 Tbio Enzyme -2.64302 437.0 263
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.74921 49.0 107
Flap endonuclease GEN homolog 1 GEN1 Tbio Enzyme -2.07325 115.0 76
Endonuclease 8-like 3 NEIL3 Tbio Enzyme -1.53902 37.4 137
Deoxyribonuclease-2-beta DNASE2B Tbio Enzyme -1.48823 30.9 74
tRNA-splicing endonuclease subunit Sen2 TSEN2 Tbio Enzyme -1.02188 10.4 140
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.34177 2054.3 327