Development Level

Tbio 13 | 11,178
Tchem 2 | 1,885

IMPC Phenotype

abnormal retina morphology 1 | 71
absent spleen 1 | 3
decreased bone mineral density 1 | 126
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 11 | 7,766
Carcinoma 8 | 11,192
group 3 medulloblastoma 8 | 4,002
Cancer 7 | 2,388
ovarian cancer 7 | 8,297
psoriasis 7 | 6,514
malignant mesothelioma 6 | 3,135
medulloblastoma, large-cell 6 | 6,086
Autosomal recessive predisposition 5 | 1,407
Breast cancer 5 | 3,469
atypical teratoid / rhabdoid tumor 5 | 4,971
glioblastoma 5 | 5,635
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,204
Cockayne syndrome 4 | 59
Xeroderma pigmentosum group G 4 | 16
lung cancer 4 | 4,607
primitive neuroectodermal tumor 4 | 2,957
Bloom syndrome 3 | 29
Xeroderma pigmentosum 3 | 42
adult high grade glioma 3 | 3,701
colon cancer 3 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,902
invasive ductal carcinoma 3 | 2,867
lung adenocarcinoma 3 | 2,627
non primary Sjogren syndrome sicca 3 | 861
non-small cell lung cancer 3 | 2,799
Adenomatous Polyposis Coli 2 | 16
Arsenic Poisoning 2 | 60
Basal cell carcinoma 2 | 54
Basal cell nevi 2 | 23
Cataract 2 | 290
Cognitive delay 2 | 596
Colorectal Neoplasms 2 | 235
Colorectal adenoma 2 | 15
Crohn's disease 2 | 311
Decreased platelet count 2 | 110
Dry skin 2 | 74
Electroencephalogram abnormal 2 | 100
Endometrial cancer 2 | 301
Endometriosis 2 | 521
Enophthalmos 2 | 74
Failure to gain weight 2 | 359
Fanconi anemia 2 | 56
Fever 2 | 136
Genetic Predisposition to Disease 2 | 26
Global developmental delay 2 | 596
Hypogonadism 2 | 169
Infantile onset 2 | 236
Intellectual disability 2 | 998
Kidney cancer 2 | 2,548
Lens Opacities 2 | 227
Low Vision 2 | 167
Lynch syndrome 2 | 34
Melanoma 2 | 689
Mental and motor retardation 2 | 596
Neoplasm Metastasis 2 | 160
Neoplasms, Germ Cell and Embryonal 2 | 15
Pediatric failure to thrive 2 | 359
Peripheral Nervous System Diseases 2 | 49
Peripheral Neuropathy 2 | 131
Photosensitivity of skin 2 | 51
Sensorineural Hearing Loss (disorder) 2 | 281
Short stature 2 | 514
Small head 2 | 366
Stomach Neoplasms 2 | 287
Sunken eyes 2 | 62
Testicular Neoplasms 2 | 6
Thrombocytopenia 2 | 193
Visual Impairment 2 | 167
Waldenstrons macroglobulinemia 2 | 742
XFE progeroid syndrome 2 | 3
Xeroderma pigmentosum group F 2 | 21
Xerosis 2 | 74
ductal carcinoma in situ 2 | 1,686
hepatocellular carcinoma 2 | 536
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,872
nasopharyngeal carcinoma 2 | 1,024
ulcerative colitis 2 | 1,765
Almond-shaped eyes 1 | 23
Atrophic condition of skin 1 | 24
Chromosome Aberrations 1 | 16
Colorectal Adenomatous Polyposis, Autosomal Recessive 1 | 1
Cystic nephroma 1 | 4
High pitched voice 1 | 23
MYH-associated polyposis 1 | 1
Multiple colonic adenomatous polyps 1 | 3
Papule 1 | 42
Peripheral demyelinating neuropathy 1 | 7
Pneumonia, Interstitial 1 | 5
Poikiloderma 1 | 14
Precociously senile appearance 1 | 18
Prominent metopic ridge 1 | 15
Pyridoxine-responsive sideroblastic anemia 1 | 17
Radial aplasia/hypoplasia 1 | 27
Rigid spine muscular dystrophy 1 1 | 14
Splayed metaphyses 1 | 18
Squamous cell carcinoma of skin 1 | 10
Thumb aplasia 1 | 16
Vitelliform macular dystrophy 1 | 14
alcohol use disorder 1 | 11

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192

Target Family

Enzyme 13 | 4,145
Non-IDG 2 | 12,091

PANTHER Protein Class (2)

endodeoxyribonuclease 15 | 15
protein kinase 252 | 252
ribosomal protein 149 | 149
mRNA processing factor 118 | 118
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease 98 | 98
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 85 | 85
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
cysteine protease 58 | 58
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
metalloprotease 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
aspartic protease 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
interleukin superfamily 4 | 4
C2H2 zinc finger transcription... 3 | 3
CREB-related transcription fac... 3 | 3
DNA photolyase 2 | 2
DNA topoisomerase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.86910 750.8 255
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.05993 1094.2 84
Exonuclease 1 EXO1 Tbio Enzyme -2.64302 437.0 263
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.74921 49.0 107
Endonuclease 8-like 3 NEIL3 Tbio Enzyme -1.53902 37.4 137
Flap endonuclease GEN homolog 1 GEN1 Tbio Enzyme -2.07325 115.0 76
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.34177 2054.3 327
tRNA-splicing endonuclease subunit Sen2 TSEN2 Tbio Enzyme -1.02188 10.4 140
Deoxyribonuclease-2-beta DNASE2B Tbio Enzyme -1.48823 30.9 74