Development Level

Tbio 26 | 11,178
Tchem 26 | 1,885
Tdark 6 | 6,569

IMPC Phenotype

preweaning lethality, complete... 3 | 979
increased circulating glucose ... 2 | 24
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal spine curvature 1 | 9
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
cataract 1 | 92
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating serum al... 1 | 82
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased startle reflex 1 | 112
long tibia 1 | 25
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 41 | 11,192
ovarian cancer 29 | 8,297
osteosarcoma 26 | 7,766
psoriasis 26 | 6,514
glioblastoma 23 | 5,635
Cancer 22 | 2,388
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,204
lung cancer 20 | 4,607
malignant mesothelioma 18 | 3,135
lung carcinoma 17 | 2,755
diabetes mellitus 16 | 1,683
medulloblastoma, large-cell 16 | 6,086
non-small cell lung cancer 14 | 2,799
subependymal giant cell astrocytoma 14 | 2,230
Breast cancer 13 | 3,469
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,872
ulcerative colitis 13 | 1,765
Astrocytoma, Pilocytic 12 | 3,006
invasive ductal carcinoma 12 | 2,867
lung adenocarcinoma 12 | 2,627
adult high grade glioma 11 | 3,701
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,902
pancreatic cancer 11 | 2,322
atypical teratoid / rhabdoid tumor 10 | 4,971
cutaneous lupus erythematosus 10 | 1,016
juvenile dermatomyositis 10 | 1,147
Liver Cirrhosis, Experimental 9 | 733
cystic fibrosis 9 | 1,629
group 3 medulloblastoma 9 | 4,002
Alzheimer's disease 8 | 640
Multiple myeloma 8 | 1,296
ependymoma 8 | 4,559
interstitial cystitis 8 | 2,237
oligodendroglioma 8 | 2,768
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,911
tuberculosis 8 | 1,963
Atopic dermatitis 7 | 915
Autosomal recessive predisposition 7 | 1,407
adrenocortical carcinoma 7 | 1,385
colon cancer 7 | 1,428
Myocardial Reperfusion Injury 6 | 35
Neurodegenerative disease 6 | 402
Stomach Neoplasms 6 | 287
Vascular disease 6 | 294
primary Sjogren syndrome 6 | 710
Arthritis 5 | 276
Bipolar Disorder 5 | 646
Chronic hepatitis C 5 | 12
Duchenne muscular dystrophy 5 | 587
Kidney cancer 5 | 2,548
Melanoma 5 | 689
Parkinson's disease 5 | 378
Toxic encephalopathy 5 | 139
acute quadriplegic myopathy 5 | 1,133
astrocytic glioma 5 | 2,530
breast carcinoma 5 | 1,589
gastric carcinoma 5 | 781
nephrosclerosis 5 | 314
Carcinoma, Hepatocellular 4 | 217
Endometriosis 4 | 521
Fascioliasis 4 | 17
Kidney disease 4 | 411
Leukemia, Myelocytic, Acute 4 | 120
Leukemia, Myeloid, Acute 4 | 105
Liver carcinoma 4 | 229
Obesity 4 | 655
Pick disease 4 | 1,856
Rheumatoid arthritis 4 | 1,156
active Crohn's disease 4 | 882
active ulcerative colitis 4 | 736
acute myeloid leukemia 4 | 760
aldosterone-producing adenoma 4 | 646
dermatomyositis 4 | 941
esophageal adenocarcinoma 4 | 696
group 4 medulloblastoma 4 | 1,806
non-small cell lung carcinoma 4 | 302
pituitary cancer 4 | 1,915
primary pancreatic ductal adenocarcinoma 4 | 1,071
spina bifida 4 | 1,053
Dementia 3 | 172
Diabetes Mellitus, Non-Insulin-Dependent 3 | 140
Diabetes Mellitus, Type 2 3 | 136
Heart disease 3 | 288
Myopathy 3 | 185
Osteoporosis 3 | 348
Pneumonia 3 | 169
Prostatic Neoplasms 3 | 472
Retinal Detachment 3 | 51
Schizophrenia 3 | 1,136
Status Epilepticus 3 | 96
Waldenstrons macroglobulinemia 3 | 742
astrocytoma 3 | 1,113
atypical teratoid/rhabdoid tumor 3 | 349
hepatocellular carcinoma 3 | 536
hereditary spastic paraplegia 3 | 313
nasopharyngeal carcinoma 3 | 1,024
pancreatic carcinoma 3 | 555
pediatric high grade glioma 3 | 1,035
periodontitis 3 | 280
posterior fossa group A ependymoma 3 | 456

Tissue

Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Skin and soft tissues 57 | 17,230
Blood and immune system 56 | 16,909
Female tissues 55 | 17,400
Male tissues 55 | 17,142
Urinary Tract 55 | 16,678
Liver and Pancreas 54 | 16,750
Respiratory system 54 | 16,393
Nervous System 52 | 16,725
Cardiovascular System 50 | 15,192

Target Family

Enzyme 35 | 4,145
Non-IDG 23 | 12,091

PANTHER Protein Class (2)

cysteine protease 58 | 58
protein kinase 252 | 252
ribosomal protein 149 | 149
mRNA processing factor 118 | 118
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease 98 | 98
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 85 | 85
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
metalloprotease 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
aspartic protease 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
interleukin superfamily 4 | 4
C2H2 zinc finger transcription... 3 | 3
CREB-related transcription fac... 3 | 3
DNA photolyase 2 | 2
DNA topoisomerase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
OTU domain-containing protein 5 OTUD5 Tbio Non-IDG -0.89861 6.92 100
Cathepsin Z CTSZ Tchem Enzyme -1.80363 70.2 233
OTU domain-containing protein 6A OTUD6A Tbio Non-IDG 0.48 0.00000 95
Cathepsin B CTSB Tchem Enzyme -3.72723 5011.5 448
Caspase-6 CASP6 Tchem Enzyme -2.49135 293.6 874
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Cathepsin F CTSF Tchem Enzyme -1.64606 49.4 178
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Calpain-14 CAPN14 Tdark Non-IDG -0.55232 4.56 19