Development Level

Tbio 71 | 11,651
Tdark 22 | 6,593
Tchem 13 | 1,388

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal embryo size 7 | 220
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased leukocyte cell numbe... 3 | 73
edema 3 | 59
abnormal bone structure 2 | 187
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal tail morphology 2 | 25
abnormal vertebral arch morpho... 2 | 9
decreased hematocrit 2 | 46
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating creatine... 2 | 5
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased IgG2b level 1 | 4
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased kidney weight 1 | 1
decreased lactate dehydrogenas... 1 | 16
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased respiratory quotient 1 | 2
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
narrow eye opening 1 | 12
pallor 1 | 34
thrombocytosis 1 | 27
tremors 1 | 39
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 66 | 11,493
osteosarcoma 57 | 7,950
ovarian cancer 56 | 8,520
medulloblastoma, large-cell 35 | 6,241
psoriasis 33 | 6,694
group 3 medulloblastoma 32 | 4,104
glioblastoma 31 | 5,792
Breast cancer 28 | 3,578
Cancer 25 | 2,499
atypical teratoid / rhabdoid tumor 25 | 5,112
lung cancer 25 | 4,740
malignant mesothelioma 23 | 3,232
primitive neuroectodermal tumor 20 | 3,035
Kidney cancer 19 | 2,613
oligodendroglioma 18 | 2,850
adult high grade glioma 17 | 3,801
ependymoma 17 | 4,679
diabetes mellitus 14 | 1,728
Rheumatoid arthritis 13 | 1,191
tuberculosis 13 | 2,010
lung adenocarcinoma 12 | 2,716
Multiple myeloma 11 | 1,332
astrocytic glioma 11 | 2,597
pituitary cancer 11 | 1,972
Astrocytoma, Pilocytic 10 | 3,081
Pick disease 10 | 1,894
astrocytoma 10 | 1,146
group 4 medulloblastoma 10 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Alzheimer's disease 9 | 658
Intellectual disability 9 | 1,016
progressive supranuclear palsy 9 | 676
subependymal giant cell astrocytoma 9 | 2,287
Short stature 8 | 531
Small head 8 | 374
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Blepharoptosis 7 | 231
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Obesity 7 | 678
Poor school performance 7 | 645
acute myeloid leukemia 7 | 783
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
juvenile dermatomyositis 7 | 1,187
Low set ears 6 | 181
Muscle hypotonia 6 | 571
Strabismus 6 | 270
Ventricular Septal Defects 6 | 119
Waldenstrons macroglobulinemia 6 | 765
aldosterone-producing adenoma 6 | 665
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
spina bifida 6 | 1,074
Adenoid Cystic Carcinoma 5 | 99
Agenesis of corpus callosum 5 | 83
Atrial Septal Defects 5 | 85
Byzanthine arch palate 5 | 194
Carcinoma, Adenoid Cystic 5 | 99
Congenital Epicanthus 5 | 177
Cryptorchidism 5 | 296
Delayed speech and language development 5 | 112
Feeding difficulties in infancy 5 | 175
Language Delay 5 | 112
Schizophrenia 5 | 1,160
Speech Delay 5 | 112
Speech impairment 5 | 112
Squamous cell carcinoma 5 | 129
dermatomyositis 5 | 966
gastric cancer 5 | 459
gastric carcinoma 5 | 807
hepatocellular carcinoma 5 | 547
medulloblastoma 5 | 720
pancreatic cancer 5 | 2,398
pediatric high grade glioma 5 | 1,064
primary pancreatic ductal adenocarcinoma 5 | 1,109
sonic hedgehog group medulloblastoma 5 | 467
tuberculosis and treatment for 6 months 5 | 409
Acquired scoliosis 4 | 281
Attention deficit hyperactivity disorder 4 | 278
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Broad flat nasal bridge 4 | 236
Curvature of spine 4 | 282
Delayed bone age 4 | 136
Down syndrome 4 | 499
Epilepsy 4 | 792
Long philtrum 4 | 137
Nasal bridge wide 4 | 236
Seizures 4 | 596
Vascular disease 4 | 319
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478

Tissue

Endocrine System 99 | 18,159
Blood and immune system 97 | 16,909
Female tissues 96 | 17,400
Nervous System 96 | 16,725
Skin and soft tissues 96 | 17,230
Cardiovascular System 95 | 15,192
Digestive Tract 95 | 17,369
Liver and Pancreas 95 | 16,750
Male tissues 95 | 17,142
Respiratory system 95 | 16,393
Urinary Tract 94 | 16,678

Target Family

Non-IDG 56 | 12,091
Epigenetic 34 | 242
Transcription Factor 7 | 1,400
TF/Epigenetic 5 | 38
Enzyme 4 | 4,145

PANTHER Protein Class (2)

chromatin/chromatin-binding pr... 106 | 106
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromatin assembly factor 1 subunit A CHAF1A Tbio Non-IDG -1.60312 40.7 157
Chromatin assembly factor 1 subunit B CHAF1B Tbio Non-IDG -1.02167 9.99 181
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial SIRT4 Tbio Epigenetic -2.14139 133.9 254
Transcriptional repressor p66-beta GATAD2B Tbio Transcription Factor -1.00210 9.37 215
Lethal(3)malignant brain tumor-like protein 1 L3MBTL1 Tchem TF/Epigenetic -2.45676 284.5 106
Histone chaperone ASF1B ASF1B Tbio Non-IDG -0.99330 10.5 155
Paired amphipathic helix protein Sin3a SIN3A Tbio Non-IDG -1.93639 70.1 171
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Transcriptional repressor p66-alpha GATAD2A Tbio Non-IDG -0.85553 8.21 159
Polyhomeotic-like protein 3 PHC3 Tbio Non-IDG -2.74734 526.7 71