Development Level

Tbio 1 | 11,445

Disease

Abnormal blistering of the skin 1 | 54
Abnormality of female internal genitalia 1 | 13
Abnormality of the fingernails 1 | 51
Abnormality of the pharynx 1 | 19
Alopecia 1 | 115
Anal mucosal leukoplakia 1 | 2
Anemia 1 | 365
Anorectal Malformations 1 | 8
Aplasia/Hypoplasia of the skin 1 | 16
Atrophic condition of skin 1 | 25
Blepharitis 1 | 23
Blister of skin 1 | 54
Blood Coagulation Disorders 1 | 42
Bone marrow hypocellularity 1 | 20
Bowen-Conradi syndrome 1 | 16
Cellular immunodeficiency 1 | 17
Cellulitis of eyelid 1 | 17
Cerebral atrophy 1 | 178
Coagulation abnormalities 1 | 27
Congenital phimosis 1 | 4
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Decreased platelet count 1 | 111
Dental caries 1 | 164
Dilated ventricles (finding) 1 | 121
Dyskeratosis congenita 1 | 24
Dystrophia unguium 1 | 53
Early tooth exfoliation 1 | 17
Esophageal Stenosis 1 | 15
Excessive tearing 1 | 12
Excessive wrinkled skin 1 | 16
Frequent fractures 1 | 53
Generalized hyperpigmentation 1 | 22
Generalized hypopigmentation of hair 1 | 5
Gingival Diseases 1 | 19
HOYERAAL-HREIDARSSON SYNDROME 1 | 6
Hemoglobin low 1 | 124
Hemorrhagic Disorders 1 | 30
Hodgkin Disease 1 | 15
Horseshoe Kidney 1 | 16
Hyperhidrosis disorder 1 | 81
Hyperpigmentation 1 | 37
Hyperpigmented macules 1 | 42
Hypodontia 1 | 81
Hypoplastic myelodysplasia 1 | 18
Hypoplastic-absent toenails 1 | 11
Immunologic Deficiency Syndromes 1 | 113
Increased fracture rate 1 | 53
Increased sweating 1 | 81
Large elongated pulp chamber 1 | 14
Leukemia, Myelocytic, Acute 1 | 120
Leukokeratosis 1 | 19
Leukopenia 1 | 72
Leukoplakia, Oral 1 | 20
Liver Cirrhosis 1 | 181
Longitudinal split nail 1 | 2
MYELODYSPLASTIC SYNDROME 1 | 53
Malabsorption 1 | 82
Malignant Squamous Cell Neoplasm 1 | 17
Microcephaly 1 | 166
Muscle Hypertonia 1 | 88
Neutrophil abnormality 1 | 20
Osteoporosis 1 | 363
Pancytopenia 1 | 45
Pediatric failure to thrive 1 | 365
Penile hypospadias 1 | 106
Periodontal Diseases 1 | 21
Premature canities 1 | 24
Premature tooth loss 1 | 17
Pterygium of nail 1 | 3
Pulmonary Fibrosis 1 | 106
Recurrent respiratory infections 1 | 141
Restrictive lung disease 1 | 11
Restrictive ventilatory defect 1 | 11
Reticular pigmentation pattern 1 | 7
Reticulate acropigmentation of Kitamura 1 | 9
Reticulate skin pigmentation 1 | 7
Ridged nails 1 | 14
Rotting teeth 1 | 73
Rough bone trabeculation 1 | 11
Shwachman-Diamond syndrome 1 | 17
Skin Ulcer 1 | 48
Skin bulla 1 | 54
Small testicle 1 | 75
Sparse eyelashes 1 | 31
Sparse hair 1 | 59
Sparse scalp hair 1 | 42
Squamous cell carcinoma 1 | 129
Sweating 1 | 81
Taurodontism 1 | 14
Telangiectasia of the skin 1 | 39
Thin, sparse hair 1 | 59
Thrombocytopenia 1 | 197
Tracheoesophageal Fistula 1 | 36
Urethral Stricture 1 | 18
Varying degree of multiple fractures 1 | 53
X- linked recessive 1 | 110
X-Linked Dyskeratosis Congenita 1 | 1
hypopigmented skin patch 1 | 59
pseudo-TORCH syndrome 1 | 5

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Non-IDG 1 | 12,091

PANTHER Protein Class (2)

centromere DNA-binding protein 1 | 1
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
H/ACA ribonucleoprotein complex subunit 4 DKC1 Tbio Non-IDG -2.39893 245.4 289