Development Level

Tchem 4 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal retinal vasculature m... 1 | 27
abnormal vocalization 1 | 21
decreased bone mineral density 1 | 126
decreased neutrophil cell numb... 1 | 42
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
preweaning lethality, incomple... 1 | 499
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24

Disease

osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
acute quadriplegic myopathy 3 | 1,158
ductal carcinoma in situ 3 | 1,745
invasive ductal carcinoma 3 | 2,951
Carcinoma 2 | 11,493
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
fructose-1,6-bisphosphatase deficiency 2 | 7
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
Alopecia areata 1 | 41
Apnea 1 | 45
Arsenic Poisoning 1 | 62
Atopic dermatitis 1 | 952
Autosomal recessive predisposition 1 | 1,442
Biotin deficiency 1 | 10
Bipolar Disorder 1 | 666
Breast cancer 1 | 3,578
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Celiac disease 1 | 116
Colonic Neoplasms 1 | 142
Comatose 1 | 56
Cystic fibrosis of the lung 1 | 2
Dermatologic disorders 1 | 93
Duchenne muscular dystrophy 1 | 601
Dyspnea 1 | 76
Elevated heart rate 1 | 25
Epilepsy 1 | 792
Fever 1 | 138
Fructose-1,6-Diphosphatase Deficiency 1 | 1
Hepatomegaly 1 | 285
Hyperventilation 1 | 6
Hypoglycemia 1 | 152
Irritation - emotion 1 | 68
Ketonemia 1 | 11
Ketosis 1 | 11
Kidney cancer 1 | 2,613
Lactic acidosis 1 | 51
Lethargy 1 | 77
Liver carcinoma 1 | 240
Major Depressive Disorder 1 | 301
Mental Depression 1 | 333
Metabolic acidosis 1 | 90
Mood Disorders 1 | 184
Muscle hypotonia 1 | 571
Myocardial Ischemia 1 | 169
Obesity 1 | 678
Parkinson Disease 1 | 64
Rheumatoid arthritis 1 | 1,191
Schizophrenia 1 | 1,160
Seizures 1 | 596
Skin Diseases 1 | 71
Stomach Neoplasms 1 | 300
Tachycardia 1 | 43
Unipolar Depression 1 | 250
active ulcerative colitis 1 | 764
acute myeloid leukemia 1 | 783
astrocytoma 1 | 1,146
atypical teratoid / rhabdoid tumor 1 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
ependymoma 1 | 4,679
esophageal adenocarcinoma 1 | 737
fibroadenoma 1 | 559
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
interstitial cystitis 1 | 2,312
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
type 2 diabetes 1 | 9
ulcerative colitis 1 | 1,819
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Enzyme 3 | 4,145
Kinase 3 | 634

PANTHER Protein Class (2)

carbohydrate phosphatase 6 | 6
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 PFKFB4 Tchem Enzyme -1.28108 21.2 110
Fructose-1,6-bisphosphatase 1 FBP1 Tchem Enzyme -2.06824 111.8 202
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 PFKFB2 Tchem Kinase -1.65270 45.8 315
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 PFKFB1 Tbio Kinase -1.33284 17.6 214
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 PFKFB3 Tchem Kinase -2.28070 206.0 228
Fructose-1,6-bisphosphatase isozyme 2 FBP2 Tbio Enzyme -2.05630 110.1 144