Development Level

Tbio 13 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
cataract 1 | 92
decreased circulating alkaline... 1 | 46
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
small epididymis 1 | 3
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Carcinoma 14 | 11,493
osteosarcoma 7 | 7,950
psoriasis 7 | 6,694
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
ovarian cancer 5 | 8,520
Autosomal recessive predisposition 4 | 1,442
Epilepsy 4 | 792
Seizures 4 | 596
pancreatic cancer 4 | 2,398
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Low set ears 3 | 181
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Myopathy 3 | 185
Poor school performance 3 | 645
Short stature 3 | 531
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
group 3 medulloblastoma 3 | 4,104
Aland Island eye disease 2 | 11
Autosomal recessive nonsyndromic deafness 8 2 | 6
Carcinoma, Hepatocellular 2 | 228
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Chromosome Xp21 deletion syndrome 2 | 8
Creatine phosphokinase serum increased 2 | 110
Duchenne muscular dystrophy 2 | 601
Elevated creatine kinase 2 | 110
Exercise-induced myoglobinuria in adults 2 | 4
Frontal bossing 2 | 157
Glycerol kinase deficiency 2 | 10
Glycogen storage disease 2 | 39
Hemiplegia 2 | 25
Hepatomegaly 2 | 285
Hernia, Inguinal 2 | 89
Hypogonadotropic hypogonadism 2 | 89
Impaired exercise tolerance 2 | 42
Intermittent migraine headaches 2 | 68
Large bregma sutures 2 | 46
Large fontanelle 2 | 46
Large, late-closing fontanelle 2 | 46
Lens Opacities 2 | 231
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Migraine Disorders 2 | 76
Multiple myeloma 2 | 1,332
Muscle cramps with exertion 2 | 7
Myocardial Ischemia 2 | 169
Myoglobinuria, exercise-induced 2 | 4
Orbital separation excessive 2 | 244
Reticulocytosis 2 | 20
Splenomegaly 2 | 190
Wide bregma sutures 2 | 46
X- linked recessive 2 | 110
X-linked adrenal hypoplasia congenita 2 | 11
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
glioblastoma 2 | 5,792
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
Aphthous stomatitis 1 | 16
Cholelithiasis 1 | 33
Distal myopathy, Nonaka type 1 | 2
Downturned corners of mouth 1 | 48
EMG positive sharp waves 1 | 2
EMG: myopathic abnormalities 1 | 22
EMG: myotonic discharges 1 | 2
Familial cold autoinflammatory syndrome 1 | 10
Fatty replacement of skeletal muscle 1 | 3
Foot dorsiflexor weakness 1 | 27
Gastrointestinal Hemorrhage 1 | 52
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Limited shoulder movement 1 | 3
Limited wrist extension 1 | 2
NONAKA MYOPATHY 1 | 2
Papule 1 | 43
Photosensitivity of skin 1 | 51
Reduced erythrocyte 2,3-diphosphoglycerate concentration 1 | 2
Reflex, Ankle, Absent 1 | 8
Renal clear cell carcinoma 1 | 6
Rimmed vacuoles on biopsy 1 | 15
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Sialuria 1 | 9
Sleep Apnea Syndromes 1 | 13
Tibialis muscle weakness 1 | 2
Weakness of hip flexors 1 | 2

Tissue

Endocrine System 17 | 18,159
Blood and immune system 15 | 16,909
Female tissues 15 | 17,400
Male tissues 15 | 17,142
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Liver and Pancreas 14 | 16,750
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Kinase 16 | 634
Enzyme 1 | 4,145

PANTHER Protein Class (2)

carbohydrate kinase 17 | 17
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphoglycerate kinase 1 PGK1 Tchem Kinase -2.79738 602.5 340
Xylulose kinase XYLB Tbio Kinase -1.97293 93.1 74
Galactokinase GALK1 Tbio Kinase -2.57441 372.4 197
Glycerate kinase GLYCTK Tbio Kinase -1.31760 20.4 192
Putative glycerol kinase 5 GK5 Tbio Kinase -0.89318 6.79 145
ATP-dependent 6-phosphofructokinase, muscle type PFKM Tbio Kinase -2.50086 308.0 311
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase GNE Tbio Enzyme -2.45989 288.1 185
Glycerol kinase 3 GK3P Tdark Kinase -1.84692 109.0 0
N-acetylgalactosamine kinase GALK2 Tbio Kinase -1.25867 17.2 203
Sedoheptulokinase SHPK Tbio Kinase -2.20263 157.8 103