Development Level

Tbio 77 | 11,445
Tdark 31 | 6,588
Tchem 3 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
cardiovascular system phenotyp... 2 | 36
enlarged spleen 2 | 41
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal incisor morphology 1 | 4
abnormal liver morphology 1 | 17
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
absent pinna reflex 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart rate variabili... 1 | 13
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
enlarged seminal vesicle 1 | 10
enlarged testis 1 | 6
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
long tibia 1 | 25
small seminal vesicle 1 | 10
small thymus 1 | 16

Disease

ovarian cancer 49 | 8,520
psoriasis 48 | 6,694
osteosarcoma 41 | 7,950
Carcinoma 39 | 11,493
glioblastoma 37 | 5,792
ependymoma 31 | 4,679
medulloblastoma, large-cell 30 | 6,241
atypical teratoid / rhabdoid tumor 28 | 5,112
lung cancer 28 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
lung carcinoma 27 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
non-small cell lung cancer 26 | 2,890
Breast cancer 25 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
lung adenocarcinoma 25 | 2,716
Astrocytoma, Pilocytic 24 | 3,081
invasive ductal carcinoma 24 | 2,951
pancreatic cancer 23 | 2,398
group 3 medulloblastoma 22 | 4,104
adult high grade glioma 19 | 3,801
pituitary cancer 17 | 1,972
subependymal giant cell astrocytoma 17 | 2,287
cystic fibrosis 16 | 1,696
interstitial cystitis 15 | 2,312
tuberculosis 15 | 2,010
breast carcinoma 14 | 1,638
ductal carcinoma in situ 14 | 1,745
malignant mesothelioma 14 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Cancer 13 | 2,499
primary pancreatic ductal adenocarcinoma 13 | 1,109
primitive neuroectodermal tumor 13 | 3,035
astrocytic glioma 12 | 2,597
nasopharyngeal carcinoma 12 | 1,058
diabetes mellitus 11 | 1,728
gastric carcinoma 11 | 807
Atopic dermatitis 10 | 952
Liver Cirrhosis, Experimental 10 | 769
esophageal adenocarcinoma 10 | 737
oligodendroglioma 10 | 2,850
Duchenne muscular dystrophy 9 | 601
Kidney cancer 9 | 2,613
adrenocortical carcinoma 9 | 1,428
colon cancer 9 | 1,478
ulcerative colitis 9 | 1,819
Waldenstrons macroglobulinemia 8 | 765
active Crohn's disease 8 | 922
acute quadriplegic myopathy 8 | 1,158
juvenile dermatomyositis 8 | 1,187
mucosa-associated lymphoid tissue lymphoma 8 | 484
spina bifida 8 | 1,074
Autosomal recessive predisposition 7 | 1,442
limb girdle muscular dystrophy 2A 7 | 213
medulloblastoma 7 | 720
pediatric high grade glioma 7 | 1,064
Amyotrophic lateral sclerosis 6 | 451
Becker muscular dystrophy 6 | 191
Hypertrophic Cardiomyopathy 6 | 117
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
chronic lymphosyte leukemia 6 | 204
cutaneous lupus erythematosus 6 | 1,057
dermatomyositis 6 | 966
non primary Sjogren syndrome sicca 6 | 891
Alzheimer's disease 5 | 658
Arachnodactyly 5 | 49
Cutis Laxa 5 | 39
Down syndrome 5 | 499
Keloid 5 | 37
Melanoma 5 | 711
Multiple myeloma 5 | 1,332
Orbital separation excessive 5 | 244
Rheumatoid arthritis 5 | 1,191
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
atypical teratoid/rhabdoid tumor 5 | 357
fibroadenoma 5 | 559
group 4 medulloblastoma 5 | 1,855
sonic hedgehog group medulloblastoma 5 | 467
Acquired scoliosis 4 | 281
Congestive heart failure 4 | 113
Curvature of spine 4 | 282
Endometriosis 4 | 540
Generalized elastolysis 4 | 24
Hanging skin 4 | 24
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Mitral valve insufficiency 4 | 49
Muscle hypotonia 4 | 571
Pectus excavatum 4 | 100
Polycystic ovary syndrome 4 | 360
Pulmonary emphysema 4 | 48
Short stature 4 | 531
Vasospasm, Intracranial 4 | 5
Weill-Marchesani syndrome 4 | 14
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
inflammatory breast cancer 4 | 286
non diabetic and post-ischemic heart failure 4 | 200

Tissue

Endocrine System 100 | 18,159
Digestive Tract 97 | 17,369
Skin and soft tissues 97 | 17,230
Female tissues 96 | 17,400
Male tissues 95 | 17,142
Blood and immune system 93 | 16,909
Liver and Pancreas 93 | 16,750
Nervous System 93 | 16,725
Urinary Tract 93 | 16,678
Respiratory system 88 | 16,393
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 85 | 12,091
Enzyme 20 | 4,145
Transporter 8 | 473

PANTHER Protein Class (2)

calmodulin 113 | 113
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-binding mitochondrial carrier protein SCaMC-3 SLC25A23 Tbio Transporter -0.72246 7.27 53
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Protein S100-Z S100Z Tbio Non-IDG -0.55434 3.71 91
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
Putative UPF0607 protein ENSP00000383144 N/A Tdark Non-IDG 0.00000 0
Protein S100-A14 S100A14 Tbio Non-IDG -1.26543 22.8 50
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Mitochondrial coenzyme A transporter SLC25A42 SLC25A42 Tbio Transporter -0.53750 4.06 29
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100