Development Level

Tbio 47 | 10,625
Tdark 10 | 7,003
Tchem 3 | 1,890

IMPC Term

decreased lean body mass 4 | 195
preweaning lethality, complete... 4 | 633
abnormal behavior 2 | 226
abnormal behavioral response t... 2 | 52
abnormal bone structure 2 | 131
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal placenta size 2 | 10
abnormal sleep behavior 2 | 63
convulsive seizures 2 | 11
decreased body length 2 | 108
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased grip strength 2 | 123
decreased leukocyte cell numbe... 2 | 54
hemorrhage 2 | 12
hyperactivity 2 | 108
increased circulating alkaline... 2 | 119
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 128
persistence of hyaloid vascula... 2 | 22
abnormal bone mineralization 1 | 55
abnormal cornea morphology 1 | 24
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal forebrain morphology 1 | 4
abnormal glucose homeostasis 1 | 5
abnormal head morphology 1 | 10
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal motor coordination/ b... 1 | 4
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal skin coloration 1 | 18
abnormal tail morphology 1 | 17
abnormal vocalization 1 | 21
absent heartbeat 1 | 6
absent pinna reflex 1 | 21
absent startle reflex 1 | 15
anophthalmia 1 | 20
corneal opacity 1 | 25
cyanosis 1 | 6
decreased Ly6C low monocyte nu... 1 | 23
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased urine creatinine lev... 1 | 2
decreased vertical activity 1 | 22
edema 1 | 11
embryonic lethality prior to t... 1 | 187
fused cornea and lens 1 | 4
fused phalanges 1 | 1
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased CD8-positive, alpha-... 1 | 11
increased Ly6C high monocyte n... 1 | 12
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased circulating chloride... 1 | 43
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
pale liver 1 | 5
pale yolk sac 1 | 12
pallor 1 | 13
prenatal lethality prior to he... 1 | 64
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

Carcinoma 33 | 2,147
osteosarcoma 27 | 7,933
ovarian cancer 27 | 8,484
psoriasis 26 | 6,685
glioblastoma 20 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
malignant mesothelioma 16 | 3,162
medulloblastoma, large-cell 16 | 6,234
non-small cell lung cancer 16 | 2,798
primitive neuroectodermal tumor 16 | 3,031
lung cancer 15 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
Breast cancer 13 | 3,094
atypical teratoid / rhabdoid tumor 13 | 4,369
invasive ductal carcinoma 13 | 2,950
acute quadriplegic myopathy 12 | 1,157
ependymoma 12 | 2,514
lung carcinoma 12 | 2,844
pilocytic astrocytoma 12 | 3,086
adult high grade glioma 11 | 2,148
pediatric high grade glioma 11 | 2,712
sonic hedgehog group medulloblastoma 11 | 1,482
ulcerative colitis 11 | 2,087
ductal carcinoma in situ 10 | 1,745
lung adenocarcinoma 10 | 2,713
oligodendroglioma 10 | 2,849
Sensorineural hearing loss 9 | 107
astrocytic glioma 9 | 2,241
interstitial cystitis 9 | 2,299
pancreatic cancer 9 | 2,300
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Distal arthrogryposis 7 | 45
Nonsyndromic deafness 7 | 121
diabetes mellitus 7 | 1,663
Cardiomyopathy 6 | 110
cystic fibrosis 6 | 1,665
gastric carcinoma 6 | 832
medulloblastoma 6 | 1,524
posterior fossa group B ependymoma 6 | 1,530
spina bifida 6 | 1,064
Duchenne muscular dystrophy 5 | 602
Myopathy 5 | 128
Nemaline myopathy 5 | 17
Pick disease 5 | 1,893
atypical teratoid/rhabdoid tumor 5 | 1,095
breast carcinoma 5 | 1,614
colon cancer 5 | 1,475
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
progressive supranuclear palsy 5 | 674
tuberculosis 5 | 1,557
Cardiomyopathy, Hypertrophic, Familial 4 | 21
Clubfoot 4 | 35
Dilated cardiomyopathy 4 | 50
Down syndrome 4 | 548
Heart disease 4 | 279
Hypertrophic Cardiomyopathy 4 | 56
Left ventricular noncompaction 4 | 23
Ophthalmoplegia 4 | 18
active Crohn's disease 4 | 918
acute myeloid leukemia 4 | 780
fibroadenoma 4 | 557
nasopharyngeal carcinoma 4 | 1,056
ARTHROGRYPOSIS, DISTAL, TYPE 1 3 | 5
ARTHROGRYPOSIS, DISTAL, TYPE 2B 3 | 5
Amyotrophic Lateral Sclerosis 3 | 431
Atopic dermatitis 3 | 944
Cardiomyopathies 3 | 90
Cardiomyopathy, Dilated 3 | 47
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 3 | 10
Congenital Fiber Type Disproportion 3 | 9
Hodgkin's lymphoma, nodular sclerosis 3 | 24
Multiple pterygium syndrome 3 | 17
Usher syndrome 3 | 34
Weight Gain 3 | 87
adrenocortical carcinoma 3 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
juvenile dermatomyositis 3 | 1,189
pancreatic carcinoma 3 | 567
Alzheimer's disease 2 | 644
Becker muscular dystrophy 2 | 187
Cancer 2 | 2,346
Cerebrovascular disease 2 | 231
Coronary artery disease 2 | 240
IGA Glomerulonephritis 2 | 454
Leukemia 2 | 88
Malignant neoplasm of prostate 2 | 67
Peripheral Neuropathy 2 | 303
chronic lymphosyte leukemia 2 | 232
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 532
inflammatory breast cancer 2 | 404
mucosa-associated lymphoid tissue lymphoma 2 | 480
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 60 | 17,995
Cardiovascular System 60 | 17,958
Female tissues 60 | 18,647
Liver and Pancreas 60 | 18,136
Male tissues 60 | 17,969
Nervous System 60 | 18,561
Digestive Tract 59 | 18,473
Endocrine System 59 | 18,512
Respiratory system 59 | 17,484
Skin and soft tissues 59 | 18,115
Urinary Tract 59 | 18,444

Target Family

Non-IDG 58 | 11,971
Kinase 2 | 634

PANTHER Protein Class (2)

actin binding motor protein 60 | 60
protein kinase 370 | 370
KRAB box transcription factor 333 | 333
serine protease 285 | 285
homeobox transcription factor 221 | 221
ribosomal protein 216 | 216
protein phosphatase 169 | 169
guanyl-nucleotide exchange fac... 168 | 168
chromatin/chromatin-binding pr... 164 | 164
non-motor actin binding protei... 161 | 161
small GTPase 130 | 130
mRNA processing factor 129 | 129
serine protease inhibitor 119 | 119
calmodulin 105 | 105
ligand-gated ion channel 104 | 104
translation factor 96 | 96
metalloprotease 75 | 75
kinase activator 72 | 72
microtubule binding motor prot... 69 | 69
potassium channel 68 | 68
RNA helicase 67 | 67
cysteine protease 62 | 62
histone 62 | 62
non-motor microtubule binding ... 60 | 60
chemokine 48 | 48
ribonucleoprotein 48 | 48
kinase inhibitor 47 | 47
nucleotide kinase 46 | 46
DNA-directed RNA polymerase 43 | 43
type I cytokine receptor 43 | 43
DNA helicase 42 | 42
centromere DNA-binding protein 42 | 42
phospholipase 42 | 42
endoribonuclease 41 | 41
calcium channel 37 | 37
heterotrimeric G-protein 35 | 35
interleukin superfamily 35 | 35
nucleotide phosphatase 35 | 35
ATP synthase 34 | 34
phosphatase inhibitor 33 | 33
actin and actin related protei... 30 | 30
neuropeptide 30 | 30
exoribonuclease 27 | 27
aspartic protease 24 | 24
tumor necrosis factor receptor 23 | 23
DNA-directed DNA polymerase 22 | 22
anion channel 21 | 21
carbohydrate kinase 21 | 21
tubulin 21 | 21
guanylate cyclase 20 | 20
cysteine protease inhibitor 17 | 17
interferon superfamily 17 | 17
endodeoxyribonuclease 16 | 16
DNA methyltransferase 15 | 15
RNA methyltransferase 13 | 13
carbohydrate phosphatase 13 | 13
CREB transcription factor 12 | 12
type II cytokine receptor 12 | 12
damaged DNA-binding protein 11 | 11
intermediate filament binding ... 11 | 11
tumor necrosis factor family m... 11 | 11
neurotrophic factor 9 | 9
sodium channel 9 | 9
replication origin binding pro... 8 | 8
DNA strand-pairing protein 7 | 7
DNA topoisomerase 4 | 4
amino acid kinase 4 | 4
exodeoxyribonuclease 4 | 4
TGF-beta receptor 3 | 3
metalloprotease inhibitor 3 | 3
DNA glycosylase 2 | 2
DNA photolyase 2 | 2
DNA polymerase processivity fa... 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1
voltage-gated ion channel 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rab effector MyRIP MYRIP Tbio Non-IDG -1.02418 12.6 110
Myosin-3 MYH3 Tbio Non-IDG -1.66510 45.6 38
Troponin T, slow skeletal muscle TNNT1 Tbio Non-IDG -3.42398 2740.6 124
Coiled-coil domain-containing protein 171 CCDC171 Tdark Non-IDG 0.27 0.42 40
Coiled-coil domain-containing protein 150 CCDC150 Tdark Non-IDG 0.00000 8
Myelin-associated oligodendrocyte basic protein MOBP Tbio Non-IDG -1.32707 21.9 121
Unconventional myosin-Vb MYO5B Tbio Non-IDG -1.91437 87.2 28
CDK5 regulatory subunit-associated protein 2 CDK5RAP2 Tbio Non-IDG -1.62892 48.2 71
Unconventional myosin-XVI MYO16 Tbio Non-IDG -0.79284 6.35 32
Melanophilin MLPH Tbio Non-IDG -1.54295 38.3 108