Development Level

Tbio 24 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

decreased body weight 3 | 161
abnormal behavior 2 | 298
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal locomotor activation 1 | 16
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
stereotypic behavior 1 | 3
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 23 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
glioblastoma 12 | 5,792
psoriasis 12 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
Autosomal recessive predisposition 9 | 1,442
Kidney cancer 9 | 2,613
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
primitive neuroectodermal tumor 8 | 3,035
Astrocytoma, Pilocytic 7 | 3,081
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
Liver Cirrhosis, Experimental 6 | 769
Sensorineural hearing loss 6 | 106
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
ulcerative colitis 6 | 1,819
Nonsyndromic deafness 5 | 142
gastric carcinoma 5 | 807
pediatric high grade glioma 5 | 1,064
Cardiomyopathy, Dilated 4 | 83
Nemaline myopathy 4 | 17
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
fibroadenoma 4 | 559
medulloblastoma 4 | 720
Acquired scoliosis 3 | 281
Byzanthine arch palate 3 | 194
Cardiomyopathy 3 | 116
Congenital myopathy 3 | 16
Curvature of spine 3 | 282
Distal arthrogryposis 3 | 42
Griscelli syndrome 3 | 24
Liver cancer 3 | 604
Motor delay 3 | 147
Muscle hypotonia 3 | 571
Myopathy 3 | 185
Narrow face 3 | 54
Nemaline rods 3 | 7
No development of motor milestones 3 | 147
Prenatal onset 3 | 139
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
Schizophrenia 3 | 1,160
Thin face 3 | 54
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
Adducted thumb 2 | 22
Arthrogryposis 2 | 54
Blepharoptosis 2 | 231
Bulbar palsy 2 | 19
Bulbar weakness 2 | 19
Cardiovascular system disease 2 | 246
Class III malocclusion 2 | 78
Clubfoot 2 | 39
Congestive heart failure 2 | 113
Decreased to absent deep tendon reflexes 2 | 42
Downward slant of palpebral fissure 2 | 158
Esophageal Squamous Cell Carcinoma 2 | 77
Flexion contracture of proximal interphalangeal joint 2 | 75
Generalized muscle weakness 2 | 57
Heart failure 2 | 162
Hypertrophic Cardiomyopathy 2 | 117
Mandibular hyperplasia 2 | 78
Multiple pterygium syndrome 2 | 18
Neck muscle weakness 2 | 17
Neonatal Hypotonia 2 | 64
Overlapping fingers 2 | 10
Protruding ears 2 | 56
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Recurrent respiratory infections 2 | 141
Reduced fetal movement 2 | 51
Sensorineural Hearing Loss (disorder) 2 | 284
Squamous cell carcinoma of esophagus 2 | 77
Triangular face 2 | 58
Usher syndrome 2 | 32
Vertical Talus 2 | 25

Tissue

Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Digestive Tract 26 | 17,369
Liver and Pancreas 26 | 16,750
Nervous System 26 | 16,725
Urinary Tract 26 | 16,678
Blood and immune system 25 | 16,909
Male tissues 25 | 17,142
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 27 | 12,091

PANTHER Protein Class (2)

actin binding motor protein 27 | 27
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Myelin-associated oligodendrocyte basic protein MOBP Tbio Non-IDG -1.36705 23.4 133
Unconventional myosin-Ia MYO1A Tbio Non-IDG -1.93292 88.7 45
Unconventional myosin-Ic MYO1C Tbio Non-IDG -1.89688 82.6 117
Unconventional myosin-Ih MYO1H Tdark Non-IDG -0.56690 3.82 16
Unconventional myosin-Ie MYO1E Tbio Non-IDG -1.68967 54.5 101
Unconventional myosin-Ib MYO1B Tbio Non-IDG -1.76878 60.8 85
Unconventional myosin-Ig MYO1G Tbio Non-IDG -1.98465 98.3 35