Development Level

Tbio 23 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

abnormal behavior 2 | 298
embryonic lethality prior to o... 2 | 239
preweaning lethality, complete... 2 | 979
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
embryonic lethality prior to t... 1 | 278
increased aggression 1 | 4
increased circulating potassiu... 1 | 29
increased grip strength 1 | 41
increased total body fat amoun... 1 | 134
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 25 | 11,493
ovarian cancer 19 | 8,520
medulloblastoma, large-cell 17 | 6,241
osteosarcoma 17 | 7,950
group 3 medulloblastoma 16 | 4,104
Cancer 14 | 2,499
primitive neuroectodermal tumor 14 | 3,035
lung cancer 13 | 4,740
atypical teratoid / rhabdoid tumor 12 | 5,112
malignant mesothelioma 12 | 3,232
Breast cancer 11 | 3,578
Cockayne syndrome 10 | 60
glioblastoma 10 | 5,792
psoriasis 10 | 6,694
Baller-Gerold syndrome 9 | 12
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
Intellectual disability 8 | 1,016
Rothmund-Thomson syndrome 8 | 19
Waldenstrons macroglobulinemia 8 | 765
colon cancer 8 | 1,478
Autosomal recessive predisposition 7 | 1,442
Multiple myeloma 7 | 1,332
Photosensitive trichothiodystrophy 7 | 30
Warsaw breakage syndrome 7 | 11
adrenocortical carcinoma 7 | 1,428
adult high grade glioma 7 | 3,801
invasive ductal carcinoma 7 | 2,951
Dull intelligence 6 | 645
Fetal Growth Retardation 6 | 189
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
Kidney cancer 6 | 2,613
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Short stature 6 | 531
Small head 6 | 374
Werner syndrome 6 | 29
Xeroderma pigmentosum group D 6 | 33
nasopharyngeal carcinoma 6 | 1,058
Congenital deafness 5 | 185
Cryptorchidism 5 | 296
Deafness 5 | 198
Fanconi anemia 5 | 56
Hearing Loss, Partial 5 | 185
ependymoma 5 | 4,679
hearing impairment 5 | 199
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Atrophic condition of skin 4 | 25
Bloom syndrome 4 | 29
Cataract 4 | 297
Cognitive delay 4 | 608
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Global developmental delay 4 | 608
Hypogonadism 4 | 173
Lens Opacities 4 | 231
Mental and motor retardation 4 | 608
Pediatric failure to thrive 4 | 365
Rapadilino syndrome 4 | 7
Seizures 4 | 596
Strabismus 4 | 270
Telangiectasia of the skin 4 | 39
Xeroderma pigmentosum 4 | 43
pediatric high grade glioma 4 | 1,064
Abnormally small eyeball 3 | 97
Basal cell carcinoma 3 | 54
Basal cell nevi 3 | 23
Brittle hair 3 | 25
Cerebellar Ataxia 3 | 304
Decreased size of eyeball 3 | 97
Dental abnormalities 3 | 60
Dental caries 3 | 164
Endometriosis 3 | 540
Hydrocephalus 3 | 152
Hyperkeratosis 3 | 50
Hyperpigmented macules 3 | 42
Liver cancer 3 | 604
Macrostomia 3 | 72
Microcephaly 3 | 166
Microphthalmos 3 | 100
Muscle hypotonia 3 | 571
Optic Atrophy 3 | 242
Photosensitivity of skin 3 | 51
Poikiloderma 3 | 14
Premature canities 3 | 24
Reduced tensile strength of hair 3 | 25
Roberts syndrome 3 | 15
Sparse scalp hair 3 | 42
Tooth Abnormalities 3 | 69
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
hypopigmented skin patch 3 | 59
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850

Tissue

Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678

Target Family

Enzyme 13 | 4,145
Non-IDG 13 | 12,091
Epigenetic 2 | 242

PANTHER Protein Class (2)

DNA helicase 28 | 28
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
Regulator of telomere elongation helicase 1 RTEL1 Tbio Enzyme -2.66156 233.0 85
ATPase WRNIP1 WRNIP1 Tbio Enzyme -2.55209 340.4 166
Fanconi anemia group J protein BRIP1 Tbio Non-IDG -1.81875 78.3 223
ATP-dependent DNA helicase Q1 RECQL Tbio Enzyme -1.87053 80.0 73
Putative ATP-dependent RNA helicase DDX11-like protein 8 DDX11L8 Tdark Enzyme -1.05592 30.0 0
Minichromosome maintenance domain-containing protein 2 MCMDC2 Tdark Non-IDG 0.18 1.14 63
DNA replication licensing factor MCM2 MCM2 Tbio Non-IDG -2.41622 246.0 777