Development Level

Tbio 22 | 11,178
Tdark 5 | 6,569
Tchem 1 | 1,885

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased or absent threshold ... 1 | 101
short tibia 1 | 97

Disease

ovarian cancer 13 | 8,297
Carcinoma 12 | 11,192
osteosarcoma 10 | 7,766
Multiple myeloma 9 | 1,296
psoriasis 8 | 6,514
Pick disease 7 | 1,856
astrocytic glioma 7 | 2,530
ependymoma 7 | 4,559
glioblastoma 6 | 5,635
medulloblastoma, large-cell 6 | 6,086
oligodendroglioma 6 | 2,768
atypical teratoid / rhabdoid tumor 5 | 4,971
lung cancer 5 | 4,607
lung carcinoma 5 | 2,755
Astrocytoma, Pilocytic 4 | 3,006
Autosomal recessive predisposition 4 | 1,407
Breast cancer 4 | 3,469
Osteopetrosis 4 | 42
diabetes mellitus 4 | 1,683
group 3 medulloblastoma 4 | 4,002
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,911
primitive neuroectodermal tumor 4 | 2,957
subependymal giant cell astrocytoma 4 | 2,230
3-methylglutaconic aciduria 3 | 29
Epilepsy 3 | 775
Failure to gain weight 3 | 359
Kidney cancer 3 | 2,548
Neuronal ceroid lipofuscinosis 3 | 28
Parkinson's disease 3 | 378
Pediatric failure to thrive 3 | 359
Spindle cell hemangioma 3 | 16
Waldenstrons macroglobulinemia 3 | 742
adult high grade glioma 3 | 3,701
breast carcinoma 3 | 1,589
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,204
invasive ductal carcinoma 3 | 2,867
lung adenocarcinoma 3 | 2,627
malignant mesothelioma 3 | 3,135
pediatric high grade glioma 3 | 1,035
Alzheimer's disease 2 | 640
Anemia 2 | 353
Congenital deafness 2 | 180
Cutis Laxa 2 | 39
Deafness 2 | 193
Dental caries 2 | 157
Dull intelligence 2 | 634
Frontal bossing 2 | 154
Gaucher disease type 1 2 | 177
Growth delay 2 | 112
Growth failure 2 | 112
Growth retardation 2 | 113
Hearing Loss, Partial 2 | 180
Hip joint varus deformity - observation 2 | 23
Intellectual disability 2 | 998
Late tooth eruption 2 | 59
Leigh disease 2 | 100
Low intelligence 2 | 634
Mental Retardation 2 | 634
Mental deficiency 2 | 634
Muscle hypotonia 2 | 562
Poor growth 2 | 112
Poor school performance 2 | 634
Rotting teeth 2 | 69
Seizures 2 | 584
Very poor growth 2 | 112
astrocytoma 2 | 1,113
chronic rhinosinusitis 2 | 505
hearing impairment 2 | 194
non-small cell lung cancer 2 | 2,799
pituitary cancer 2 | 1,915
tuberculosis 2 | 1,963
Abnormality of hair volume 1 | 5
Alkaline phosphatase serum increased 1 | 28
Autosomal recessive malignant osteopetrosis 1 | 4
Calcinosis 1 | 63
Coarse hair 1 | 31
Decreased projection of midface 1 | 104
Dehydration 1 | 39
Diphyllobothriasis 1 | 6
Flatfoot 1 | 71
Fragile nails 1 | 16
Generalized osteopenia 1 | 94
Hypokalemia 1 | 50
Hypokalemic periodic paralysis 1 | 11
Hypotrophic midface 1 | 104
Increased calcium level in kidney 1 | 21
Kearns-Sayre syndrome 1 | 7
Kyphosis deformity of spine 1 | 112
Metabolic acidosis 1 | 89
Midface retrusion 1 | 104
Osteopenia 1 | 94
Osteopetrosis autosomal recessive 1 1 | 2
Osteopetrosis, Autosomal Recessive 1 1 | 2
Pathological fracture 1 | 19
Peripheral Neuropathy 1 | 131
Progressive microcephaly 1 | 32
Rough hair texture 1 | 31
Sickle Cell Anemia 1 | 50
Small midface 1 | 104
non-small cell lung carcinoma 1 | 302

Tissue

Blood and immune system 27 | 16,909
Digestive Tract 27 | 17,369
Male tissues 27 | 17,142
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Cardiovascular System 25 | 15,192
Liver and Pancreas 25 | 16,750

Target Family

Enzyme 25 | 4,145
Non-IDG 3 | 12,091

PANTHER Protein Class (2)

ATP synthase 28 | 28
protein kinase 252 | 252
ribosomal protein 149 | 149
mRNA processing factor 118 | 118
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease 98 | 98
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 85 | 85
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
cysteine protease 58 | 58
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
metalloprotease 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
DNA helicase 28 | 28
actin binding motor protein 27 | 27
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
aspartic protease 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
interleukin superfamily 4 | 4
C2H2 zinc finger transcription... 3 | 3
CREB-related transcription fac... 3 | 3
DNA photolyase 2 | 2
DNA topoisomerase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Germinal-center associated nuclear protein MCM3AP Tbio Non-IDG -1.74285 63.4 158
ATP synthase subunit epsilon, mitochondrial ATP5F1E Tbio Enzyme -1.86682 69.6 105
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.76 118
Leukocyte receptor cluster member 8 LENG8 Tdark Non-IDG 0.43 0.00000 29
ATP synthase F(0) complex subunit C1, mitochondrial ATP5MC1 Tbio Enzyme -1.19949 13.4 100
V-type proton ATPase subunit S1 ATP6AP1 Tchem Enzyme -1.94689 91.3 166
V-type proton ATPase 21 kDa proteolipid subunit ATP6V0B Tbio Enzyme -0.96261 10.7 81
V-type proton ATPase subunit G 2 ATP6V1G2 Tbio Enzyme -0.88393 7.05 52
SAC3 domain-containing protein 1 SAC3D1 Tdark Non-IDG -0.79375 5.91 9
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90