Development Level

Tbio 50 | 11,651
Tchem 15 | 1,388
Tdark 9 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
decreased body weight 3 | 161
increased startle reflex 3 | 112
abnormal embryo size 2 | 220
decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hemorrhage 2 | 23
increased body length 2 | 32
increased circulating creatini... 2 | 38
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
absent teeth 1 | 3
anophthalmia 1 | 33
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating potassiu... 1 | 29
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased fluid intake 1 | 1
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
mydriasis 1 | 6
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
vertebral transformation 1 | 12

Disease

Carcinoma 55 | 11,493
ovarian cancer 39 | 8,520
osteosarcoma 36 | 7,950
Kidney cancer 27 | 2,613
psoriasis 25 | 6,694
glioblastoma 23 | 5,792
atypical teratoid / rhabdoid tumor 22 | 5,112
ependymoma 21 | 4,679
group 3 medulloblastoma 21 | 4,104
medulloblastoma, large-cell 21 | 6,241
oligodendroglioma 21 | 2,850
lung cancer 20 | 4,740
subependymal giant cell astrocytoma 18 | 2,287
malignant mesothelioma 17 | 3,232
Breast cancer 15 | 3,578
Cancer 15 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
non-small cell lung cancer 12 | 2,890
primitive neuroectodermal tumor 12 | 3,035
astrocytic glioma 11 | 2,597
Pick disease 10 | 1,894
adult high grade glioma 10 | 3,801
astrocytoma 10 | 1,146
pituitary cancer 10 | 1,972
Astrocytoma, Pilocytic 9 | 3,081
Intellectual disability 9 | 1,016
group 4 medulloblastoma 9 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
ductal carcinoma in situ 8 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
interstitial cystitis 7 | 2,312
juvenile dermatomyositis 7 | 1,187
lung adenocarcinoma 7 | 2,716
non primary Sjogren syndrome sicca 7 | 891
spina bifida 7 | 1,074
tuberculosis 7 | 2,010
acute quadriplegic myopathy 6 | 1,158
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
lung carcinoma 6 | 2,843
pediatric high grade glioma 6 | 1,064
Liver cancer 5 | 604
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
acute myeloid leukemia 5 | 783
posterior fossa group B ependymoma 5 | 416
primary pancreatic ductal adenocarcinoma 5 | 1,109
sonic hedgehog group medulloblastoma 5 | 467
ulcerative colitis 5 | 1,819
Autism spectrum disorder 4 | 101
Autistic Disorder 4 | 364
Craniofacial Abnormalities 4 | 151
Cryptorchidism 4 | 296
Dandy-Walker Syndrome 4 | 39
Hypothyroidism 4 | 122
Melanoma 4 | 711
Multiple myeloma 4 | 1,332
Townes-Brocks syndrome 4 | 15
adrenocortical carcinoma 4 | 1,428
cystic fibrosis 4 | 1,696
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
tuberculosis and treatment for 6 months 4 | 409
Adenoid Cystic Carcinoma 3 | 99
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Attention deficit hyperactivity disorder 3 | 278
Azoospermia 3 | 110
Carcinoma, Adenoid Cystic 3 | 99
Congenital hypoplasia of penis 3 | 176
Down syndrome 3 | 499
Duane-radial ray syndrome 3 | 8
Dull intelligence 3 | 645
Hydronephrosis 3 | 89
Low intelligence 3 | 645
Male infertility 3 | 206
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Osteoporosis 3 | 363
Penile hypospadias 3 | 106
Poor school performance 3 | 645
Specific language impairment 3 | 34
aldosterone-producing adenoma 3 | 665
atypical teratoid/rhabdoid tumor 3 | 357
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
progressive supranuclear palsy 3 | 676
Aggressive behavior 2 | 75
Cardia cancer 2 | 3
Endometrial cancer 2 | 311
Heart disease 2 | 306
Language Delay 2 | 112
Motor neuron disease 2 | 49
Speech impairment 2 | 112
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764

Tissue

Endocrine System 73 | 18,159
Nervous System 70 | 16,725
Digestive Tract 69 | 17,369
Female tissues 69 | 17,400
Skin and soft tissues 69 | 17,230
Blood and immune system 68 | 16,909
Male tissues 67 | 17,142
Liver and Pancreas 65 | 16,750
Urinary Tract 65 | 16,678
Respiratory system 64 | 16,393
Cardiovascular System 60 | 15,192

Target Family

Transcription Factor 38 | 1,400
Epigenetic 17 | 242
Non-IDG 11 | 12,091
TF/Epigenetic 5 | 38
Nuclear Receptor 2 | 48
Enzyme 1 | 4,145

PANTHER Protein Class (1)

zinc finger transcription fact... 74 | 74
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Teashirt homolog 2 TSHZ2 Tbio Non-IDG -0.01649 0.78 90
Lysine-specific demethylase 4E KDM4E Tchem Epigenetic -0.86891 5.72 23
Four and a half LIM domains protein 3 FHL3 Tbio Non-IDG -0.71819 5.67 103
Sal-like protein 2 SALL2 Tbio Transcription Factor -1.68783 51.1 68
PHD finger protein 14 PHF14 Tbio Epigenetic -0.69202 5.79 72
Zinc finger HIT domain-containing protein 1 ZNHIT1 Tdark Non-IDG -0.41378 2.04 99
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Lysine-specific demethylase 4B KDM4B Tchem Epigenetic -1.59502 40.6 449
Zinc finger protein ZFPM1 ZFPM1 Tbio Transcription Factor -2.52665 326.6 82
Four and a half LIM domains protein 5 FHL5 Tbio Non-IDG -0.60566 3.43 116