Development Level

Tbio 30 | 11,445
Tdark 10 | 6,588

IMPC Phenotype

abnormal seminal vesicle morph... 2 | 114
decreased circulating choleste... 2 | 93
enlarged seminal vesicle 2 | 10
preweaning lethality, complete... 2 | 979
abnormal cecum morphology 1 | 7
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased grip strength 1 | 116
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged heart 1 | 210
hydroencephaly 1 | 14
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating aspartat... 1 | 15
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27

Disease

ovarian cancer 29 | 8,520
osteosarcoma 22 | 7,950
glioblastoma 19 | 5,792
Carcinoma 17 | 11,493
ependymoma 14 | 4,679
psoriasis 14 | 6,694
Multiple myeloma 13 | 1,332
medulloblastoma, large-cell 13 | 6,241
atypical teratoid / rhabdoid tumor 12 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Breast cancer 9 | 3,578
adult high grade glioma 9 | 3,801
lung adenocarcinoma 9 | 2,716
Kidney cancer 8 | 2,613
acute quadriplegic myopathy 8 | 1,158
invasive ductal carcinoma 8 | 2,951
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
pancreatic cancer 8 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pituitary cancer 8 | 1,972
Astrocytoma, Pilocytic 7 | 3,081
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
primitive neuroectodermal tumor 7 | 3,035
astrocytic glioma 6 | 2,597
dermatomyositis 6 | 966
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non-small cell lung cancer 6 | 2,890
Menkes disease 5 | 19
astrocytoma 5 | 1,146
diabetes mellitus 5 | 1,728
group 4 medulloblastoma 5 | 1,855
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Cognitive delay 4 | 608
Gaucher disease type 1 4 | 180
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Autosomal recessive predisposition 3 | 1,442
Intellectual disability 3 | 1,016
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Waldenstrons macroglobulinemia 3 | 765
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Big calvaria 2 | 147
Bulbous nasal tip 2 | 48
Bulbous nose 2 | 48
Byzanthine arch palate 2 | 194
Cancer 2 | 2,499
Cataract 8 multiple types 2 | 33
Cholestasis 2 | 155
Coarse facial features 2 | 108
Curvature of spine 2 | 282
DiGeorge syndrome 2 | 47
Diffuse large B-cell lymphoma 2 | 39
Down syndrome 2 | 499
Hydrocephalus 2 | 152
Hypoparathyroidism 2 | 41
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Leber congenital amaurosis 2 | 69
Liver Cirrhosis, Experimental 2 | 769
Long face 2 | 71
Lymphoma, Large B-Cell, Diffuse 2 | 34
Potato nose 2 | 48
Prenatal onset 2 | 139
Stomatitis 2 | 21
Tetralogy of Fallot 2 | 63
Thickened facial skin with coarse facial features 2 | 108
Upward slant of palpebral fissure 2 | 75
Wilson disease 2 | 16
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
hereditary spastic paraplegia 2 | 318
non primary Sjogren syndrome sicca 2 | 891
posterior fossa group A ependymoma 2 | 468
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
Congenital hypoplasia of kidney 1 | 32

Tissue

Blood and immune system 40 | 16,909
Cardiovascular System 40 | 15,192
Digestive Tract 40 | 17,369
Endocrine System 40 | 18,159
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Respiratory system 40 | 16,393
Skin and soft tissues 40 | 17,230
Urinary Tract 40 | 16,678

Target Family

Non-IDG 40 | 12,091

PANTHER Protein Class (1)

vesicle coat protein 40 | 40
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
Transmembrane emp24 domain-containing protein 1 TMED1 Tdark Non-IDG -0.57403 3.74 106
Transmembrane emp24 domain-containing protein 5 TMED5 Tbio Non-IDG -0.27107 1.67 29
Transmembrane emp24 domain-containing protein 9 TMED9 Tdark Non-IDG -0.03714 0.58 112
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Clathrin heavy chain linker domain-containing protein 1 CLHC1 Tdark Non-IDG 1.49 0.03 17
Transmembrane emp24 domain-containing protein 4 TMED4 Tbio Non-IDG -1.79946 61.9 105
AP-3 complex subunit sigma-2 AP3S2 Tdark Non-IDG -0.27930 1.66 66
Clathrin light chain A CLTA Tbio Non-IDG -1.32676 16.0 244