Development Level

Tbio 75 | 11,445
Tdark 12 | 6,588
Tchem 9 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal coat-hair pigmentatio... 2 | 64
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal retinal inner nuclear... 1 | 8
abnormal skin coloration 1 | 25
cataract 1 | 92
decreased bone mineral density 1 | 126
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hyperactivity 1 | 148
increased body temperature 1 | 9
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
male infertility 1 | 123
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 61 | 11,493
ovarian cancer 56 | 8,520
osteosarcoma 52 | 7,950
psoriasis 42 | 6,694
glioblastoma 40 | 5,792
medulloblastoma, large-cell 39 | 6,241
atypical teratoid / rhabdoid tumor 34 | 5,112
ependymoma 33 | 4,679
lung cancer 33 | 4,740
group 3 medulloblastoma 29 | 4,104
Breast cancer 24 | 3,578
Astrocytoma, Pilocytic 23 | 3,081
astrocytic glioma 22 | 2,597
adult high grade glioma 21 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
malignant mesothelioma 21 | 3,232
lung adenocarcinoma 20 | 2,716
oligodendroglioma 20 | 2,850
primitive neuroectodermal tumor 20 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
invasive ductal carcinoma 19 | 2,951
Pick disease 18 | 1,894
astrocytoma 18 | 1,146
non-small cell lung cancer 18 | 2,890
Cancer 17 | 2,499
Kidney cancer 16 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
juvenile dermatomyositis 16 | 1,187
subependymal giant cell astrocytoma 16 | 2,287
lung carcinoma 15 | 2,843
colon cancer 14 | 1,478
acute quadriplegic myopathy 13 | 1,158
breast carcinoma 13 | 1,638
dermatomyositis 13 | 966
group 4 medulloblastoma 13 | 1,855
pancreatic cancer 13 | 2,398
pituitary cancer 12 | 1,972
interstitial cystitis 11 | 2,312
tuberculosis 11 | 2,010
Multiple myeloma 10 | 1,332
acute myeloid leukemia 10 | 783
primary pancreatic ductal adenocarcinoma 10 | 1,109
ulcerative colitis 10 | 1,819
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
aldosterone-producing adenoma 8 | 665
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
adrenocortical carcinoma 7 | 1,428
pediatric high grade glioma 7 | 1,064
spina bifida 7 | 1,074
Liver cancer 6 | 604
Mental Depression 6 | 333
progressive supranuclear palsy 6 | 676
Breast Neoplasms 5 | 445
Depressive disorder 5 | 409
Endometriosis 5 | 540
Intellectual disability 5 | 1,016
Mammary Neoplasms 5 | 425
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
interstitial lung disease 5 | 298
medulloblastoma 5 | 720
primary Sjogren syndrome 5 | 735
Atopic dermatitis 4 | 952
Barrett's esophagus 4 | 182
Bipolar Disorder 4 | 666
Epilepsy 4 | 792
Hypoplastic mandible condyle 4 | 275
Liver Cirrhosis, Experimental 4 | 769
Mandibular hypoplasia 4 | 275
Melanoma 4 | 711
Micrognathism 4 | 275
Multiple Sclerosis 4 | 540
Obesity 4 | 678
Polycystic ovary syndrome 4 | 360
Schizophrenia 4 | 1,160
Short stature 4 | 531
Ventricular Septal Defects 4 | 119
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
hepatocellular carcinoma 4 | 547
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Bilateral fifth finger clinodactyly 3 | 110
Broad flat nasal bridge 3 | 236
Congenital Epicanthus 3 | 177
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Down syndrome 3 | 499
Nasal bridge wide 3 | 236
Prostate cancer 3 | 175
Seizures 3 | 596
Strabismus 3 | 270
Waldenstrons macroglobulinemia 3 | 765
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
urothelial carcinoma 3 | 318

Tissue

Endocrine System 93 | 18,159
Digestive Tract 92 | 17,369
Liver and Pancreas 92 | 16,750
Male tissues 92 | 17,142
Female tissues 91 | 17,400
Respiratory system 91 | 16,393
Skin and soft tissues 91 | 17,230
Blood and immune system 90 | 16,909
Urinary Tract 90 | 16,678
Cardiovascular System 89 | 15,192
Nervous System 89 | 16,725

Target Family

Non-IDG 69 | 12,091
Enzyme 10 | 4,145
Epigenetic 9 | 242
Transcription Factor 4 | 1,400
TF/Epigenetic 2 | 38
Kinase 1 | 634
Transporter 1 | 473

PANTHER Protein Class (1)

transcription cofactor 96 | 96
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leucine-rich repeat flightless-interacting protein 2 LRRFIP2 Tbio Non-IDG -0.65733 4.88 129
Staphylococcal nuclease domain-containing protein 1 SND1 Tbio Epigenetic -2.35812 225.9 175
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
Hepatoma-derived growth factor-related protein 3 HDGFL3 Tbio Epigenetic -0.42051 3.29 139
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
RNA-binding protein 43 RBM43 Tdark Non-IDG -0.02803 0.65 70
Capping protein, Arp2/3 and myosin-I linker protein 3 CARMIL3 Tdark Non-IDG -0.46736 3.21 37
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 222
Mediator of RNA polymerase II transcription subunit 12-like protein MED12L Tbio Enzyme -0.77925 5.52 14