Development Level

Tbio 28 | 11,445
Tdark 7 | 6,588

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
absent startle reflex 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
shortened PR interval 1 | 6
shortened RR interval 1 | 17

Disease

psoriasis 16 | 6,694
Carcinoma 15 | 11,493
ovarian cancer 15 | 8,520
atypical teratoid / rhabdoid tumor 13 | 5,112
Cancer 12 | 2,499
interstitial cystitis 12 | 2,312
osteosarcoma 12 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung adenocarcinoma 11 | 2,716
non-small cell lung cancer 11 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
invasive ductal carcinoma 10 | 2,951
ductal carcinoma in situ 9 | 1,745
medulloblastoma, large-cell 9 | 6,241
pancreatic cancer 9 | 2,398
ependymoma 8 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Breast cancer 7 | 3,578
active Crohn's disease 7 | 922
subependymal giant cell astrocytoma 7 | 2,287
cystic fibrosis 6 | 1,696
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
pituitary cancer 6 | 1,972
Inflammatory bowel disease 5 | 151
lung cancer 5 | 4,740
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Diarrhea 4 | 253
Nephrocalcinosis 4 | 35
Prostatic Neoplasms 4 | 495
active ulcerative colitis 4 | 764
breast carcinoma 4 | 1,638
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
nasopharyngeal carcinoma 4 | 1,058
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
Atopic dermatitis 3 | 952
Brain Edema 3 | 50
Breast Neoplasms 3 | 445
Cerebrovascular disease 3 | 238
Cholestasis 3 | 155
Diabetic retinopathy 3 | 56
Down syndrome 3 | 499
Mammary Neoplasms 3 | 425
Multiple Sclerosis 3 | 540
Nephrolithiasis 3 | 56
Nonsyndromic deafness 3 | 142
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
interstitial lung disease 3 | 298
mucosa-associated lymphoid tissue lymphoma 3 | 484
non primary Sjogren syndrome sicca 3 | 891
Barrett's esophagus 2 | 182
Cell Transformation, Neoplastic 2 | 97
Failure to gain weight 2 | 365
Heart conduction disease 2 | 83
Irritable bowel syndrome 2 | 60
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Myopia 2 | 176
Neoplastic Cell Transformation 2 | 89
Oxyphilic adenoma 2 | 22
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Renal oncocytoma 2 | 22
Rickets 2 | 49
Splenomegaly 2 | 190
Williams-Beuren syndrome 2 | 50
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
fibroadenoma 2 | 559
hearing impairment 2 | 199
periodontitis 2 | 293
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318
Astigmatism 1 | 54
COPD 1 | 118
Dry skin 1 | 75
Hyperopia 1 | 70
Hypertension, Portal 1 | 22
Hyperuricemia 1 | 49
Neoplasm Recurrence, Local 1 | 37
Nephrosis 1 | 21
Perinatal necrotizing enterocolitis 1 | 21
Recurrent urinary tract infection 1 | 24
Renal Cell Carcinoma 1 | 214
Xerosis 1 | 75
inflammatory breast cancer 1 | 286
non-inflammatory breast cancer 1 | 66

Tissue

Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Male tissues 30 | 17,142
Liver and Pancreas 29 | 16,750
Blood and immune system 28 | 16,909
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 3 | 4,145

PANTHER Protein Class (1)

tight junction 35 | 35
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Claudin-3 CLDN3 Tbio Non-IDG -2.37681 227.3 358
Putative claudin-24 CLDN24 Tdark Non-IDG 0.15 1.06 1
Claudin-23 CLDN23 Tbio Non-IDG -0.68709 3.81 89
Claudin-5 CLDN5 Tbio Non-IDG -2.58968 349.4 300
Occludin/ELL domain-containing protein 1 OCEL1 Tdark Non-IDG 1.11 0.06 51
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.20720 1368.9 292
Claudin-4 CLDN4 Tbio Non-IDG -2.57691 369.5 428
Claudin-34 CLDN34 Tdark Non-IDG 0.00000 0