Development Level

Tbio 25 | 11,651
Tchem 7 | 1,388
Tclin 5 | 612
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 2 | 298
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased fasted circulating g... 2 | 65
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal iris morphology 1 | 13
abnormal placement of pupils 1 | 6
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal snout morphology 1 | 23
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
enlarged heart 1 | 210
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
tremors 1 | 39

Disease

ovarian cancer 22 | 8,520
psoriasis 19 | 6,694
osteosarcoma 16 | 7,950
medulloblastoma, large-cell 14 | 6,241
lung cancer 13 | 4,740
pancreatic cancer 13 | 2,398
Breast cancer 12 | 3,578
Carcinoma 12 | 11,493
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
non-small cell lung cancer 12 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
lung carcinoma 11 | 2,843
malignant mesothelioma 11 | 3,232
tuberculosis 11 | 2,010
Cancer 10 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
adrenocortical carcinoma 9 | 1,428
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
invasive ductal carcinoma 9 | 2,951
Autosomal recessive predisposition 8 | 1,442
lung adenocarcinoma 8 | 2,716
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Atopic dermatitis 7 | 952
Endometriosis 7 | 540
adult high grade glioma 7 | 3,801
interstitial cystitis 7 | 2,312
oligodendroglioma 7 | 2,850
Polycystic ovary syndrome 6 | 360
astrocytoma 6 | 1,146
nasopharyngeal carcinoma 6 | 1,058
primary pancreatic ductal adenocarcinoma 6 | 1,109
acute quadriplegic myopathy 5 | 1,158
colon cancer 5 | 1,478
group 4 medulloblastoma 5 | 1,855
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Carcinoma, Hepatocellular 4 | 228
Endometrial Neoplasms 4 | 55
Failure to gain weight 4 | 365
Hepatomegaly 4 | 285
Liver carcinoma 4 | 240
Pain 4 | 103
Pediatric failure to thrive 4 | 365
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
Acute lymphoid leukemia 3 | 25
Alcoholic Intoxication, Chronic 3 | 289
Bipolar Disorder 3 | 666
Cell Transformation, Neoplastic 3 | 97
Cognitive delay 3 | 608
Colorectal Neoplasms 3 | 243
Diabetic complication 3 | 3
Disorders of Sex Development 3 | 5
Dysmenorrhea 3 | 21
Epilepsy 3 | 792
Global developmental delay 3 | 608
Hepatitis B 3 | 108
Liver Cirrhosis, Experimental 3 | 769
Malignant tumor of head and/or neck 3 | 15
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Neoplasms, Hormone-Dependent 3 | 3
Neoplastic Cell Transformation 3 | 89
Osteoarthritis 3 | 184
Seizures 3 | 596
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
hearing impairment 3 | 199
nephrosclerosis 3 | 333
pancreatic carcinoma 3 | 562
ulcerative colitis 3 | 1,819
Anteverted nostril 2 | 191
Atrial Fibrillation 2 | 124
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Hepatic enzyme increased 2 | 81
Liver Cirrhosis 2 | 181
Liver Dysfunction 2 | 99
Liver function tests abnormal finding 2 | 81
Malaria 2 | 160
Micromelia 2 | 58
Neuropathy 2 | 261
Stomach Neoplasms 2 | 300
Strabismus 2 | 270
active Crohn's disease 2 | 922
medulloblastoma 2 | 720
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416

Tissue

Digestive Tract 40 | 17,369
Endocrine System 40 | 18,159
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Male tissues 40 | 17,142
Skin and soft tissues 40 | 17,230
Urinary Tract 40 | 16,678
Blood and immune system 39 | 16,909
Nervous System 38 | 16,725
Respiratory system 37 | 16,393
Cardiovascular System 35 | 15,192

Target Family

Enzyme 30 | 4,145
Non-IDG 11 | 12,091
Epigenetic 1 | 242

PANTHER Protein Class (1)

reductase 42 | 42
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-c1 complex subunit 6-like, mitochondrial UQCRHL Tdark Non-IDG -0.84371 11.5 0
Dihydrofolate reductase 2, mitochondrial DHFR2 Tbio Enzyme -0.37414 2.93 82
Esterase OVCA2 OVCA2 Tdark Non-IDG -0.54456 1.92 47
Aldose reductase AKR1B1 Tclin Enzyme -3.27314 1915.8 350
Lamin-B receptor LBR Tbio Epigenetic -3.02961 1057.1 134
Methionine-R-sulfoxide reductase B2, mitochondrial MSRB2 Tbio Enzyme -1.84856 71.5 120
Thioredoxin domain-containing protein 12 TXNDC12 Tbio Non-IDG -1.48767 32.4 103
Gamma-interferon-inducible lysosomal thiol reductase IFI30 Tbio Enzyme -2.16234 146.7 118
Glutaredoxin-3 GLRX3 Tbio Non-IDG -1.93135 90.3 243
3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 Tbio Enzyme -1.87479 75.7 171