Development Level

Tbio 23 | 10,625
Tchem 11 | 1,890
Tclin 5 | 602
Tdark 5 | 7,003

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
embryonic lethality prior to o... 2 | 148
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal gait 1 | 51
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal placement of pupils 1 | 4
abnormal respiratory quotient 1 | 9
abnormal response to new envir... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal snout morphology 1 | 18
cataract 1 | 26
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased red blood cell distr... 1 | 11
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating amylase ... 1 | 13
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
microcephaly 1 | 3
narrow eye opening 1 | 15
persistence of hyaloid vascula... 1 | 22
tremors 1 | 34

Disease

ovarian cancer 23 | 8,484
osteosarcoma 21 | 7,933
psoriasis 20 | 6,685
glioblastoma 16 | 5,572
medulloblastoma, large-cell 16 | 6,234
lung cancer 13 | 4,466
non-small cell lung cancer 13 | 2,798
pancreatic cancer 13 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
malignant mesothelioma 11 | 3,162
tuberculosis 11 | 1,557
Breast cancer 10 | 3,094
Cancer 10 | 2,346
ductal carcinoma in situ 10 | 1,745
ependymoma 10 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
breast carcinoma 9 | 1,614
group 4 medulloblastoma 9 | 1,875
interstitial cystitis 9 | 2,299
invasive ductal carcinoma 9 | 2,950
lung carcinoma 9 | 2,844
oligodendroglioma 9 | 2,849
subependymal giant cell astrocytoma 9 | 2,287
astrocytoma 8 | 1,493
atypical teratoid / rhabdoid tumor 8 | 4,369
lung adenocarcinoma 8 | 2,713
pituitary cancer 8 | 1,972
Atopic dermatitis 7 | 944
Endometriosis 7 | 535
adrenocortical carcinoma 7 | 1,427
pediatric high grade glioma 7 | 2,712
primary pancreatic ductal adenocarcinoma 7 | 1,271
Polycystic Ovary Syndrome 6 | 332
nasopharyngeal carcinoma 6 | 1,056
primitive neuroectodermal tumor 6 | 3,031
acute quadriplegic myopathy 5 | 1,157
astrocytic glioma 5 | 2,241
colon cancer 5 | 1,475
group 3 medulloblastoma 5 | 2,254
pilocytic astrocytoma 5 | 3,086
Endometrial Neoplasms 4 | 50
Liver carcinoma 4 | 217
Methemoglobinemia 4 | 17
Multiple myeloma 4 | 1,327
Pain 4 | 70
atypical teratoid/rhabdoid tumor 4 | 1,095
cystic fibrosis 4 | 1,665
dermatomyositis 4 | 933
esophageal adenocarcinoma 4 | 737
medulloblastoma 4 | 1,524
posterior fossa group A ependymoma 4 | 1,511
ulcerative colitis 4 | 2,087
Acute lymphoid leukemia 3 | 25
Colorectal Neoplasms 3 | 217
Diabetic complication 3 | 3
Disorders of Sex Development 3 | 5
Dysmenorrhea 3 | 19
Hepatitis B 3 | 103
IGA Glomerulonephritis 3 | 454
Malignant tumor of head and/or neck 3 | 15
Neoplasms, Hormone-Dependent 3 | 3
Neoplastic Cell Transformation 3 | 81
Rheumatoid Arthritis 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 918
adult high grade glioma 3 | 2,148
fibroadenoma 3 | 557
gastric carcinoma 3 | 832
non primary Sjogren syndrome sicca 3 | 840
pancreatic carcinoma 3 | 567
posterior fossa group B ependymoma 3 | 1,530
primary Sjogren syndrome 3 | 789
Atrial Fibrillation 2 | 110
Autistic Disorder 2 | 320
Contact Dermatitis 2 | 80
Degenerative polyarthritis 2 | 93
Duchenne muscular dystrophy 2 | 602
Malaria 2 | 140
Neuropathy 2 | 210
Pick disease 2 | 1,893
Prostatic Neoplasms 2 | 471
Stomach Neoplasms 2 | 282
Vascular disease 2 | 281
active ulcerative colitis 2 | 477
acute myeloid leukemia 2 | 780
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cystic fibrosis and chronic rhinosinusitis 2 | 213
diabetes mellitus 2 | 1,663
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
hearing impairment 2 | 40
hepatocellular carcinoma 2 | 532
juvenile dermatomyositis 2 | 1,189
limb girdle muscular dystrophy 2A 2 | 156
nephrosclerosis 2 | 329
non-small cell lung carcinoma 2 | 413
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 44 | 17,995
Cardiovascular System 44 | 17,958
Digestive Tract 44 | 18,473
Endocrine System 44 | 18,512
Female tissues 44 | 18,647
Liver and Pancreas 44 | 18,136
Male tissues 44 | 17,969
Nervous System 44 | 18,561
Respiratory system 44 | 17,484
Skin and soft tissues 44 | 18,115
Urinary Tract 44 | 18,444

Target Family

Enzyme 33 | 4,146
Non-IDG 10 | 11,971
Epigenetic 1 | 242

PANTHER Protein Class (1)

reductase 44 | 44
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
Aldo-keto reductase family 1 member B15 AKR1B15 Tbio Enzyme -0.09691 2.10 4
NADH-cytochrome b5 reductase 3 CYB5R3 Tchem Enzyme -1.93440 89.2 241
Ribonucleoside-diphosphate reductase subunit M2 B RRM2B Tbio Enzyme -1.87012 86.4 226
Dihydrofolate reductase DHFR Tclin Enzyme -2.97865 960.4 158
Glutaredoxin-3 GLRX3 Tbio Non-IDG -1.86821 85.0 198
3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 Tbio Enzyme -1.79404 68.6 142
Delta(14)-sterol reductase TM7SF2 Tbio Enzyme -1.04299 12.4 80
Esterase OVCA2 OVCA2 Tdark Non-IDG -0.38471 1.92 40
Anterior gradient protein 2 homolog AGR2 Tbio Non-IDG -2.00927 125.8 532