Development Level

Tbio 191 | 10,625
Tchem 89 | 1,890
Tdark 85 | 7,003
Tclin 10 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 11 | 633
abnormal behavior 7 | 226
preweaning lethality, incomple... 7 | 260
increased circulating alkaline... 6 | 119
decreased body length 5 | 108
decreased prepulse inhibition 5 | 52
decreased total body fat amoun... 5 | 186
short tibia 5 | 82
abnormal embryo size 4 | 112
abnormal tail morphology 4 | 17
abnormal limb morphology 3 | 7
decreased body weight 3 | 174
decreased circulating choleste... 3 | 85
decreased grip strength 3 | 123
decreased respiratory quotient 3 | 12
embryonic lethality prior to t... 3 | 187
hyperactivity 3 | 108
hypoactivity 3 | 89
abnormal QRS complex 2 | 25
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal cranium morphology 2 | 32
abnormal limb bud morphology 2 | 15
abnormal maxilla morphology 2 | 16
abnormal seminal vesicle morph... 2 | 47
abnormal skin appearance 2 | 8
abnormal sleep behavior 2 | 63
abnormal vertebral arch morpho... 2 | 9
abnormal vibrissa morphology 2 | 17
decreased bone mineral density 2 | 126
decreased cervical vertebrae n... 2 | 12
decreased circulating aspartat... 2 | 27
decreased circulating phosphat... 2 | 15
decreased circulating triglyce... 2 | 83
decreased heart weight 2 | 44
decreased lean body mass 2 | 195
decreased monocyte cell number 2 | 28
edema 2 | 11
embryonic growth retardation 2 | 28
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
hemorrhage 2 | 12
impaired glucose tolerance 2 | 52
increased B cell number 2 | 23
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased heart weight 2 | 37
increased mean corpuscular vol... 2 | 91
increased monocyte cell number 2 | 27
increased or absent threshold ... 2 | 128
increased rib number 2 | 41
increased sacral vertebrae num... 2 | 62
increased startle reflex 2 | 38
oligodactyly 2 | 14
small thymus 2 | 11
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal embryo turning 1 | 15
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
convulsive seizures 1 | 11
decreased KLRG1-positive NK ce... 1 | 9
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating sodium l... 1 | 18
decreased gamma-delta T cell n... 1 | 18
decreased hematocrit 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased pulmonary respirator... 1 | 4
decreased threshold for audito... 1 | 32
enlarged stomach 1 | 2
female infertility 1 | 34
hydrops fetalis 1 | 22
increased CD4-positive, CD25-p... 1 | 18
increased NK cell number 1 | 19
increased body length 1 | 20
increased circulating amylase ... 1 | 13
increased circulating creatini... 1 | 29
increased effector memory CD4-... 1 | 15
lethargy 1 | 5
premature death 1 | 5
short tail 1 | 4
shortened PQ interval 1 | 6
straub tail 1 | 26
trunk curl 1 | 15

Disease

ovarian cancer 168 | 8,484
osteosarcoma 167 | 7,933
psoriasis 140 | 6,685
medulloblastoma, large-cell 115 | 6,234
glioblastoma 113 | 5,572
lung cancer 102 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 95 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 89 | 2,956
atypical teratoid / rhabdoid tumor 87 | 4,369
lung carcinoma 86 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 84 | 2,988
pancreatic cancer 80 | 2,300
malignant mesothelioma 77 | 3,162
invasive ductal carcinoma 75 | 2,950
lung adenocarcinoma 74 | 2,713
non-small cell lung cancer 74 | 2,798
interstitial cystitis 66 | 2,299
pilocytic astrocytoma 64 | 3,086
ulcerative colitis 64 | 2,087
Cancer 61 | 2,346
diabetes mellitus 60 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 60 | 1,795
Breast cancer 59 | 3,094
oligodendroglioma 59 | 2,849
primitive neuroectodermal tumor 56 | 3,031
Carcinoma 55 | 2,147
cystic fibrosis 55 | 1,665
subependymal giant cell astrocytoma 55 | 2,287
pediatric high grade glioma 54 | 2,712
adult high grade glioma 49 | 2,148
Pick disease 44 | 1,893
pituitary cancer 42 | 1,972
posterior fossa group A ependymoma 41 | 1,511
tuberculosis 41 | 1,557
breast carcinoma 40 | 1,614
group 4 medulloblastoma 39 | 1,875
ductal carcinoma in situ 38 | 1,745
group 3 medulloblastoma 36 | 2,254
colon cancer 35 | 1,475
ependymoma 35 | 2,514
Alzheimer's disease 33 | 644
Atopic dermatitis 33 | 944
astrocytic glioma 33 | 2,241
primary pancreatic ductal adenocarcinoma 33 | 1,271
cutaneous lupus erythematosus 32 | 1,056
posterior fossa group B ependymoma 31 | 1,530
astrocytoma 30 | 1,493
juvenile dermatomyositis 29 | 1,189
Rheumatoid Arthritis 28 | 1,160
gastric carcinoma 27 | 832
nasopharyngeal carcinoma 27 | 1,056
adrenocortical carcinoma 26 | 1,427
medulloblastoma 26 | 1,524
Multiple myeloma 25 | 1,327
active Crohn's disease 24 | 918
esophageal adenocarcinoma 24 | 737
sonic hedgehog group medulloblastoma 24 | 1,482
Kidney disease 23 | 396
spina bifida 22 | 1,064
Duchenne muscular dystrophy 21 | 602
Obesity 21 | 616
acute quadriplegic myopathy 21 | 1,157
dermatomyositis 21 | 933
atypical teratoid/rhabdoid tumor 20 | 1,095
mucosa-associated lymphoid tissue lymphoma 20 | 480
Atherosclerosis 18 | 275
Waldenstrons macroglobulinemia 18 | 765
interstitial lung disease 18 | 291
acute myeloid leukemia 17 | 780
Anemia 16 | 252
Hypertension 16 | 287
active ulcerative colitis 16 | 477
primary Sjogren syndrome 16 | 789
Neurodegenerative disease 15 | 383
fibroadenoma 15 | 557
Down syndrome 14 | 548
Pancreatitis 14 | 97
chronic rhinosinusitis 14 | 512
Multiple Sclerosis 13 | 498
Parkinson's disease 13 | 364
Prostatic Neoplasms 13 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
inflammatory breast cancer 13 | 404
non primary Sjogren syndrome sicca 13 | 840
non-small cell lung carcinoma 13 | 413
pancreatic carcinoma 13 | 567
progressive supranuclear palsy 13 | 674
Asthma 12 | 349
Autistic Disorder 12 | 320
Cerebrovascular disease 12 | 231
Endometriosis 12 | 535
IGA Glomerulonephritis 12 | 454
Vascular disease 12 | 281
glioblastoma multiforme 12 | 347
nephrosclerosis 12 | 329
tuberculosis and treatment for 6 months 12 | 686
Arthritis 11 | 248
Intellectual disability 11 | 573
aldosterone-producing adenoma 11 | 664
urothelial carcinoma 10 | 318

Tissue

Nervous System 365 | 18,561
Endocrine System 363 | 18,512
Female tissues 363 | 18,647
Male tissues 363 | 17,969
Digestive Tract 362 | 18,473
Cardiovascular System 361 | 17,958
Urinary Tract 361 | 18,444
Liver and Pancreas 360 | 18,136
Skin and soft tissues 358 | 18,115
Blood and immune system 357 | 17,995
Respiratory system 356 | 17,484

Target Family

Enzyme 228 | 4,146
Non-IDG 140 | 11,971
Transcription Factor 6 | 1,400
Kinase 1 | 634

PANTHER Protein Class (1)

protease 375 | 375
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Seizure protein 6 homolog SEZ6 Tdark Non-IDG -0.87986 8.64 27
Tolloid-like protein 1 TLL1 Tbio Non-IDG -1.40066 23.4 60
Xaa-Pro aminopeptidase 2 XPNPEP2 Tchem Enzyme -1.55651 32.2 97
Transmembrane gamma-carboxyglutamic acid protein 3 PRRG3 Tdark Non-IDG -0.21639 1.71 76
Transmembrane gamma-carboxyglutamic acid protein 4 PRRG4 Tdark Non-IDG -0.29670 2.24 21
Ovochymase-2 OVCH2 Tdark Enzyme 0.00000 0
Serine protease 41 PRSS41 Tdark Enzyme 0.00000 0
Nardilysin NRDC Tbio Enzyme -1.64244 49.9 83
CD5 antigen-like CD5L Tbio Non-IDG -1.78447 64.4 287