Development Level

Tbio 142 | 10,625
Tchem 50 | 1,890
Tdark 37 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
abnormal bone structure 6 | 131
decreased body length 5 | 108
decreased body weight 5 | 174
decreased bone mineral content 4 | 157
decreased bone mineral density 3 | 126
decreased circulating triglyce... 3 | 83
decreased lean body mass 3 | 195
decreased neutrophil cell numb... 3 | 37
increased body weight 3 | 42
limb grasping 3 | 35
male infertility 3 | 62
thrombocytopenia 3 | 46
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
abnormal heart left ventricle ... 2 | 20
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
abnormal testis morphology 2 | 30
decreased caudal vertebrae num... 2 | 49
decreased circulating HDL chol... 2 | 77
decreased circulating glycerol... 2 | 19
decreased erythrocyte cell num... 2 | 43
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased mean corpuscular hem... 2 | 34
decreased total body fat amoun... 2 | 186
decreased total retina thickne... 2 | 20
hydrops fetalis 2 | 22
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased circulating sodium l... 2 | 71
increased heart weight 2 | 37
increased lymphocyte cell numb... 2 | 9
increased mean corpuscular hem... 2 | 93
persistence of hyaloid vascula... 2 | 22
preweaning lethality, incomple... 2 | 260
small testis 2 | 37
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal ear morphology 1 | 5
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin appearance 1 | 8
abnormal vocalization 1 | 21
anophthalmia 1 | 20
cardiovascular system phenotyp... 1 | 35
craniofacial phenotype 1 | 9
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased cervical vertebrae n... 1 | 12
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 43
increased circulating glycerol... 1 | 11
increased circulating serum al... 1 | 25
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate variabili... 1 | 4
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased prepulse inhibition 1 | 21
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
long tibia 1 | 13
microphthalmia 1 | 15
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64
small adrenal glands 1 | 15
thin ventricular wall 1 | 5
vertebral fusion 1 | 23

Disease

ovarian cancer 130 | 8,492
osteosarcoma 118 | 7,933
medulloblastoma, large-cell 103 | 6,234
glioblastoma 97 | 5,572
psoriasis 79 | 6,685
lung cancer 75 | 4,473
atypical teratoid / rhabdoid tumor 73 | 4,369
Breast cancer 51 | 3,099
ependymoma 49 | 2,514
pilocytic astrocytoma 48 | 3,086
primitive neuroectodermal tumor 46 | 3,031
Pick disease 45 | 1,893
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,289
invasive ductal carcinoma 45 | 2,950
malignant mesothelioma 45 | 3,163
pediatric high grade glioma 44 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,988
oligodendroglioma 42 | 2,849
adult high grade glioma 41 | 2,148
astrocytic glioma 41 | 2,241
subependymal giant cell astrocytoma 40 | 2,287
non-small cell lung cancer 39 | 2,798
ulcerative colitis 38 | 2,087
group 4 medulloblastoma 36 | 1,875
lung adenocarcinoma 36 | 2,714
interstitial cystitis 34 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,956
lung carcinoma 34 | 2,844
group 3 medulloblastoma 33 | 2,254
colon cancer 32 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,795
pancreatic cancer 30 | 2,300
Carcinoma 28 | 2,147
Cancer 27 | 2,346
medulloblastoma 27 | 1,524
ductal carcinoma in situ 26 | 1,745
pituitary cancer 25 | 1,972
tuberculosis 23 | 1,563
breast carcinoma 22 | 1,614
Multiple myeloma 21 | 1,328
spina bifida 21 | 1,064
astrocytoma 20 | 1,493
juvenile dermatomyositis 20 | 1,189
sonic hedgehog group medulloblastoma 20 | 1,482
cystic fibrosis 19 | 1,670
diabetes mellitus 18 | 1,663
Waldenstrons macroglobulinemia 17 | 765
active Crohn's disease 17 | 918
aldosterone-producing adenoma 17 | 664
atypical teratoid/rhabdoid tumor 17 | 1,095
cutaneous lupus erythematosus 17 | 1,056
primary pancreatic ductal adenocarcinoma 17 | 1,271
Rheumatoid Arthritis 16 | 1,171
acute quadriplegic myopathy 16 | 1,157
adrenocortical carcinoma 16 | 1,427
gastric carcinoma 16 | 832
posterior fossa group A ependymoma 16 | 1,511
posterior fossa group B ependymoma 16 | 1,530
dermatomyositis 15 | 967
esophageal adenocarcinoma 14 | 737
non primary Sjogren syndrome sicca 12 | 840
primary Sjogren syndrome 12 | 789
progressive supranuclear palsy 12 | 674
Endometriosis 11 | 535
Neurodegenerative disease 11 | 383
hereditary spastic paraplegia 11 | 313
Atopic dermatitis 10 | 944
Bipolar Disorder 10 | 266
Down syndrome 10 | 548
IGA Glomerulonephritis 10 | 454
nasopharyngeal carcinoma 10 | 1,056
Duchenne muscular dystrophy 9 | 602
acute myeloid leukemia 9 | 785
fibroadenoma 9 | 557
pancreatic carcinoma 9 | 567
Alzheimer's disease 8 | 644
Crohn's disease 8 | 304
Obesity 8 | 616
Oculocerebrorenal syndrome 8 | 24
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
glioblastoma multiforme 8 | 347
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
tuberculosis and treatment for 3 months 8 | 327
Centronuclear myopathy 7 | 21
Neuropathy 7 | 210
Peripheral Neuropathy 7 | 303
Schizophrenia 7 | 503
active ulcerative colitis 7 | 477
gastric cancer 7 | 436
hepatocellular carcinoma 7 | 550
urothelial carcinoma 7 | 318
Charcot-Marie-Tooth disease 6 | 74
Melanoma 6 | 261
Stomach Neoplasms 6 | 282
chronic lymphocytic leukemia 6 | 244
chronic rhinosinusitis 6 | 512
nephrosclerosis 6 | 329
tuberculosis and treatment for 6 months 6 | 686
Intellectual disability 5 | 573
Prostatic Neoplasms 5 | 471

Tissue

Digestive Tract 227 | 18,473
Endocrine System 227 | 18,512
Female tissues 227 | 18,647
Nervous System 227 | 18,561
Skin and soft tissues 227 | 18,115
Blood and immune system 226 | 17,995
Liver and Pancreas 226 | 18,136
Urinary Tract 226 | 18,444
Male tissues 225 | 17,969
Respiratory system 225 | 17,484
Cardiovascular System 223 | 17,958

Target Family

Enzyme 191 | 4,146
Non-IDG 34 | 11,969
Kinase 4 | 634
Ion Channel 1 | 341

PANTHER Protein Class (1)

phosphatase 230 | 230
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5'-nucleotidase domain-containing protein 3 NT5DC3 Tdark Enzyme -1.72530 52.1 19
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 ENPP5 Tdark Enzyme -0.52180 3.31 86
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.05927 116.0 218
Nucleoside diphosphate-linked moiety X motif 8 NUDT8 Tdark Non-IDG 0.00000 90
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.60562 34.9 108
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform PPP2R2C Tbio Enzyme -1.11980 11.3 62
Tensin-1 TNS1 Tbio Non-IDG -2.69701 318.0 121
Tyrosine-protein phosphatase non-receptor type 2 PTPN2 Tchem Enzyme -2.49223 269.5 174
Tyrosine-protein phosphatase non-receptor type 22 PTPN22 Tchem Enzyme -2.68153 504.5 190
Serine/threonine-protein phosphatase CPPED1 CPPED1 Tbio Enzyme -0.85594 6.97 87