Development Level

Tbio 87 | 10,625
Tchem 39 | 1,890
Tdark 30 | 7,003
Tclin 6 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased monocyte cell number 2 | 28
increased blood urea nitrogen ... 2 | 44
increased mean corpuscular hem... 2 | 93
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal retina morphology 1 | 100
abnormal snout morphology 1 | 18
abnormal testis morphology 1 | 30
abnormal tibia morphology 1 | 14
absent testes 1 | 2
convulsive seizures 1 | 11
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory T-he... 1 | 2
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased macrophage cell numb... 1 | 4
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
immune system phenotype 1 | 17
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased CD8-positive, alpha-... 1 | 11
increased CD8-positive, naive ... 1 | 3
increased circulating amylase ... 1 | 13
increased circulating chloride... 1 | 43
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased leukocyte cell numbe... 1 | 37
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
shortened RR interval 1 | 19
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

psoriasis 68 | 6,685
Cancer 49 | 2,346
ovarian cancer 45 | 8,484
diabetes mellitus 40 | 1,663
osteosarcoma 39 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,289
lung cancer 36 | 4,466
medulloblastoma, large-cell 36 | 6,234
glioblastoma 33 | 5,572
Hypertension 30 | 287
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,956
Obesity 28 | 616
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
pancreatic cancer 27 | 2,300
lung adenocarcinoma 26 | 2,713
pilocytic astrocytoma 26 | 3,086
cystic fibrosis 25 | 1,665
lung carcinoma 24 | 2,844
Hypertensive disease 23 | 193
pituitary cancer 23 | 1,972
Breast cancer 22 | 3,094
Kidney disease 21 | 396
atypical teratoid / rhabdoid tumor 21 | 4,369
invasive ductal carcinoma 21 | 2,950
colon cancer 20 | 1,475
oligodendroglioma 20 | 2,849
Adenoma 19 | 165
Cerebrovascular disease 19 | 231
Heart disease 19 | 279
adult high grade glioma 19 | 2,148
interstitial cystitis 19 | 2,299
non-small cell lung cancer 19 | 2,798
Diarrhea 18 | 155
Hypoglycemia 18 | 81
Hypotension 17 | 53
malignant mesothelioma 17 | 3,162
Coronary artery disease 16 | 240
pediatric high grade glioma 16 | 2,712
ulcerative colitis 16 | 2,087
Prostatic Neoplasms 15 | 471
adrenocortical carcinoma 15 | 1,427
breast carcinoma 15 | 1,614
Hypothyroidism 14 | 89
Pancreatitis 14 | 97
posterior fossa group A ependymoma 14 | 1,511
Acromegaly 13 | 40
Atopic dermatitis 13 | 944
Hyperinsulinism 13 | 63
Hypogonadism 13 | 70
Pain agnosia 13 | 99
Atherosclerosis 12 | 275
Bradycardia 12 | 24
Hypopituitarism 12 | 36
Pain 12 | 70
Pituitary adenoma 12 | 35
Schizophrenia 12 | 501
ependymoma 12 | 2,514
esophageal adenocarcinoma 12 | 737
fibroadenoma 12 | 557
group 3 medulloblastoma 12 | 2,254
group 4 medulloblastoma 12 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Alzheimer's disease 11 | 644
Cushing's syndrome 11 | 47
Hyperalgesia 11 | 71
posterior fossa group B ependymoma 11 | 1,530
Autistic Disorder 10 | 320
Constipation 10 | 43
Endometriosis 10 | 535
Heart failure 10 | 80
Hyperglycemia 10 | 120
Liver disease 10 | 219
Pick disease 10 | 1,893
astrocytoma 10 | 1,493
cutaneous lupus erythematosus 10 | 1,056
medulloblastoma 10 | 1,524
subependymal giant cell astrocytoma 10 | 2,287
Anorexia nervosa 9 | 59
Hyperparathyroidism 9 | 43
Hyperprolactinemia 9 | 22
Hyperthyroidism 9 | 50
Infertility 9 | 163
Metabolic syndrome X 9 | 155
Vascular disease 9 | 281
astrocytic glioma 9 | 2,241
ductal carcinoma in situ 9 | 1,745
primary pancreatic ductal adenocarcinoma 9 | 1,271
primitive neuroectodermal tumor 9 | 3,031
sonic hedgehog group medulloblastoma 9 | 1,482
Acute kidney injury 8 | 65
Anemia 8 | 252
Inflammation 8 | 109
Lung disease 8 | 132
Osteoporosis 8 | 257
Polycystic Ovary Syndrome 8 | 332
Prostate cancer 8 | 172
active Crohn's disease 8 | 918
juvenile dermatomyositis 8 | 1,189
nasopharyngeal carcinoma 8 | 1,056
tuberculosis 8 | 1,557

Tissue

Digestive Tract 151 | 18,473
Endocrine System 150 | 18,512
Female tissues 150 | 18,647
Nervous System 149 | 18,561
Liver and Pancreas 146 | 18,136
Skin and soft tissues 145 | 18,115
Urinary Tract 143 | 18,444
Blood and immune system 142 | 17,995
Cardiovascular System 139 | 17,958
Male tissues 138 | 17,969
Respiratory system 132 | 17,484

Target Family

Non-IDG 92 | 11,971
Enzyme 70 | 4,146

PANTHER Protein Class (1)

peptide hormone 162 | 162
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Transmembrane protease serine 6 TMPRSS6 Tchem Enzyme -1.99222 118.1 102
Coagulation factor XI F11 Tchem Enzyme -2.65863 487.3 216
Plasma kallikrein KLKB1 Tclin Enzyme -2.88472 708.0 231
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Transmembrane protease serine 7 TMPRSS7 Tdark Enzyme 0.24 0.97 63
Serine protease 45 PRSS45 Tdark Enzyme 0.48 0.25 14
Ovochymase-1 OVCH1 Tdark Enzyme -0.27875 1.89 48
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Calcitonin gene-related peptide 2 CALCB Tchem Non-IDG -1.55780 27.3 25