Development Level

Tbio 36 | 11,445
Tchem 17 | 1,598
Tclin 8 | 613
Tdark 7 | 6,588

IMPC Phenotype

enlarged heart 4 | 210
abnormal embryo size 3 | 220
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
abnormal seminal vesicle morph... 2 | 114
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral density 2 | 126
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hydrometra 2 | 53
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased leukocyte cell numbe... 2 | 47
increased monocyte cell number 2 | 63
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal hindbrain morphology 1 | 10
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal pupil morphology 1 | 2
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal tail bud morphology 1 | 8
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vitreous body morphol... 1 | 10
absent mammary gland 1 | 1
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased monocyte cell number 1 | 8
decreased skeletal muscle mass 1 | 1
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
enlarged seminal vesicle 1 | 10
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating unsatura... 1 | 1
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
prolonged RR interval 1 | 8
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small ovary 1 | 1
small spleen 1 | 19
small uterus 1 | 3
thin skin 1 | 2

Disease

Carcinoma 56 | 11,493
psoriasis 39 | 6,694
ovarian cancer 28 | 8,520
non-small cell lung cancer 25 | 2,890
osteosarcoma 23 | 7,950
Breast cancer 21 | 3,578
ependymoma 21 | 4,679
glioblastoma 21 | 5,792
interstitial cystitis 21 | 2,312
lung adenocarcinoma 21 | 2,716
lung cancer 21 | 4,740
lung carcinoma 19 | 2,843
medulloblastoma, large-cell 18 | 6,241
Cancer 17 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Autosomal recessive predisposition 15 | 1,442
cystic fibrosis 15 | 1,696
Astrocytoma, Pilocytic 14 | 3,081
adult high grade glioma 14 | 3,801
atypical teratoid / rhabdoid tumor 13 | 5,112
group 3 medulloblastoma 13 | 4,104
cutaneous lupus erythematosus 12 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
malignant mesothelioma 12 | 3,232
invasive ductal carcinoma 11 | 2,951
ulcerative colitis 11 | 1,819
Hypertension 10 | 396
Schizophrenia 10 | 1,160
esophageal adenocarcinoma 10 | 737
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
oligodendroglioma 10 | 2,850
Prostatic Neoplasms 9 | 495
active Crohn's disease 9 | 922
astrocytic glioma 9 | 2,597
ductal carcinoma in situ 9 | 1,745
pancreatic cancer 9 | 2,398
pituitary cancer 9 | 1,972
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Endometriosis 8 | 540
Liver Cirrhosis, Experimental 8 | 769
adrenocortical carcinoma 8 | 1,428
breast carcinoma 8 | 1,638
subependymal giant cell astrocytoma 8 | 2,287
Breast Neoplasms 7 | 445
Kidney cancer 7 | 2,613
Mammary Neoplasms 7 | 425
Pick disease 7 | 1,894
Obesity 6 | 678
adrenocortical adenoma 6 | 131
chronic rhinosinusitis 6 | 512
diabetes mellitus 6 | 1,728
medulloblastoma 6 | 720
nephrosclerosis 6 | 333
Adenocarcinoma 5 | 122
Alzheimer's disease 5 | 658
Arthritis 5 | 290
Asthma 5 | 385
Atherosclerosis 5 | 291
Barrett's esophagus 5 | 182
Chemical and Drug Induced Liver Injury 5 | 195
Cholestasis 5 | 155
Diarrhea 5 | 253
Esophageal Neoplasms 5 | 69
Hypertensive disease 5 | 292
Kidney disease 5 | 430
Liver disease 5 | 237
Osteoporosis 5 | 363
Rheumatoid arthritis 5 | 1,191
aldosterone-producing adenoma 5 | 665
astrocytoma 5 | 1,146
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
periodontitis 5 | 293
Cerebrovascular disease 4 | 238
Coronary artery disease 4 | 268
Dull intelligence 4 | 645
Failure to gain weight 4 | 365
Glaucoma 4 | 239
Growth delay 4 | 114
Growth failure 4 | 114
Growth retardation 4 | 115
Heart disease 4 | 306
Hepatomegaly 4 | 285
Liver Cirrhosis 4 | 181
Low intelligence 4 | 645
Lung Neoplasms 4 | 232
Melanoma 4 | 711
Mental deficiency 4 | 645
Osteoarthritis 4 | 184
Pediatric failure to thrive 4 | 365
Poor growth 4 | 114
Poor school performance 4 | 645
Reperfusion Injury 4 | 86
fibroadenoma 4 | 559
gastric carcinoma 4 | 807
head and neck cancer 4 | 271
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562

Tissue

Endocrine System 65 | 18,159
Female tissues 65 | 17,400
Male tissues 65 | 17,142
Digestive Tract 64 | 17,369
Liver and Pancreas 63 | 16,750
Skin and soft tissues 63 | 17,230
Blood and immune system 61 | 16,909
Nervous System 61 | 16,725
Urinary Tract 60 | 16,678
Respiratory system 57 | 16,393
Cardiovascular System 43 | 15,192

Target Family

Enzyme 52 | 4,145
Non-IDG 16 | 12,091

PANTHER Protein Class (1)

oxygenase 68 | 68
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cholesterol 24-hydroxylase CYP46A1 Tbio Enzyme -1.84856 68.6 197
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial COQ6 Tbio Enzyme -1.26796 18.5 102
Phylloquinone omega-hydroxylase CYP4F11 CYP4F11 Tbio Enzyme -0.71213 6.60 96
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
Cytochrome P450 4Z1 CYP4Z1 Tbio Non-IDG -0.68998 9.87 74
Beta,beta-carotene 9',10'-oxygenase BCO2 Tbio Enzyme -1.64030 46.1 93
4-hydroxyphenylpyruvate dioxygenase-like protein HPDL Tdark Enzyme 0.18 0.51 29
Collagen triple helix repeat-containing protein 1 CTHRC1 Tbio Non-IDG -1.72221 62.3 202